Gene Information

Name : DIP2267 (DIP2267)
Accession : NP_940570.1
Strain : Corynebacterium diphtheriae NCTC13129
Genome accession: NC_002935
Putative virulence/resistance : Unknown
Product : two component system response regulator protein
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2197
EC number : -
Position : 2359054 - 2359692 bp
Length : 639 bp
Strand : -
Note : Similar to Streptomyces coelicolor two component system DNA binding response regulator SC10A9.12 SWALL:Q9AK92 (EMBL:AL583943) (211 aa) fasta scores: E(): 7.7e-38, 59.24% id in 211 aa, and to Corynebacterium diphtheriae response regulator ChrA (DIP2327) SW

DNA sequence :
ATGATCCGAGTTTTGCTCGCTGACGATCACGAAATTGTCCGATTAGGTCTTCGAGCCGTGCTCGAAAGCGCCGAGGACAT
TGAAGTAATCGGTGAAGTAGCCACCGCTGAAGCAGCCATCGCAGCAGCACAAGCAGGCGGTATCGACGTGATCCTCATGG
ATCTGCGCTTCGGCCCAGGCGTGCAGGGGACAAAGCTCACCAGCGGTGCCGACGCAACCGCCGCCATCCGACGCCGGATG
GACAACCCACCAGAGGTGCTCGTGGTGACCAACTATGACACCGACGCGGACATCCTCGGTGCCATTGAAGCCGGAGCCCT
TGGCTACATGCTCAAAGACGCACCCCCAGAGGAACTGCTGGCAGCAGTGCGTTCGGCGGCAGAAGGCGACACCGCACTAT
CACCCACCGTGGCTAACCGCTTGATGTCGCGAGTACGTGCCCCACGAAATTCGCTCACCCCACGCGAACTGGAAGTGCTC
AAGTTGGTTGCTGGTGGCTCTTCCAACCGTGATATTGGGCGCAGGCTGCTGCTGTCTGAGGCAACGGTAAAAAGCCACCT
CGTGCACATCTATGACAAGCTAGGCGTGCGCTCCCGCACCTCGGCTGTGGCTATCGCACGAGAACAAGGCGTGCTGTAG

Protein sequence :
MIRVLLADDHEIVRLGLRAVLESAEDIEVIGEVATAEAAIAAAQAGGIDVILMDLRFGPGVQGTKLTSGADATAAIRRRM
DNPPEVLVVTNYDTDADILGAIEAGALGYMLKDAPPEELLAAVRSAAEGDTALSPTVANRLMSRVRAPRNSLTPRELEVL
KLVAGGSSNRDIGRRLLLSEATVKSHLVHIYDKLGVRSRTSAVAIAREQGVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
regB YP_001220830.1 putative two-component system response regulator Not tested chp/tomA region Protein 4e-15 42