Gene Information

Name : serS (DIP2240)
Accession : NP_940543.1
Strain : Corynebacterium diphtheriae NCTC13129
Genome accession: NC_002935
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 2329968 - 2331227 bp
Length : 1260 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
GTGATTGATCTAAAGTTACTCCGCGAAAACCCTGATGTCGTCCGCGAGTCCCAGCGCATTCGTGGCGAAGACCCAGCTCT
GGTGGATCAGCTCCTCGAGGCTGACGAGAAGCGCCGCGAGGCCATTAAGTCTGCCGACGACCTGCGCGCCGAGCACAAGG
CCTTTGGCAAGAAGATTAGCCAGGCCTCCCCAGAAGAGCGTCCCGCTTTGCTGGAGGGCTCTAACGAGCTGAAGTCCCGC
GTGAAGGCGGCGGAGGAGGCCGAGGCTGAAGCGTTGGCCAAGGTCAACGAGATCCAAATGCTGTTCGGCAACGTTGTTAC
CGATGCCCCAGCTGGTGGCGAGGATGACTACATCGTTTTGGAGCACGTAGGCACCCCACGTACCTTTGATTTCGAGCCAA
AGGATCACCTCGATCTTGGTGAGTCGCTTGGGCTTATCGACGTCAAACGCGGCACCAAGGTTGGTGGTGCACGCTTCTAC
TACCTCACCGGCGATGGCGCATTCCTACAGCTGGGCATGCTGAATCTTGCGGCGCAAAAGGCCCGCGAGAATGGCTTCCA
GCTGATGATCCCACCTGTGCTTGTCCGCCCAGAGGTCATGTCCGGTACCGGTTTCTTGGGTGCTCACTCAGATGAGATCT
ACTACCTTGAGCGCGATGACCTCTACCTCGTGGGTACCTCCGAGGTGGCGTTGGCTGGTTACCACCAGGATGAGATCATC
GATTTGTCTGATGGTCCTATCAAGTACGCGGGCTGGTCGAGCTGCTTCCGTCGTGAAGCGGGCTCCTACGGCAAGGACAC
CCGCGGTATTTTGCGCGTGCACCAGTTCGACAAGCTGGAGATGTTTGTTTACTGCAAGCCAGAAGAGGCTGTTGCGCAGC
ACCAAGCTCTGTTGAACATGGAGCGCGAGATGTTGGCTGCTGTTGAGGTGCCTTACCGCATTATCGACGTCGCCGGCGGC
GACCTTGGTTCCTCTGCTGCCCGCAAGTTTGACACTGAGGCATGGATTCCAACCCAGAACACCTACCGTGAGCTGACCTC
GACCTCGAACTGCACCACCTTCCAGGCACGTCGTCTGCGCACCCGCTACCGTGACGAGTCTGGCAAGGCACACACTGCAG
CAACCCTGAACGGTACCTTGGCTACCACGCGTTGGCTGGTCGCTATCCTTGAGAACAACCAGCAGGCTGATGGCTCGGTG
ATCGTTCCTGAGGCACTGCGCCCATTCGTGGGCAAGGAAGTACTCGAGCCAAAGAAGTAA

Protein sequence :
MIDLKLLRENPDVVRESQRIRGEDPALVDQLLEADEKRREAIKSADDLRAEHKAFGKKISQASPEERPALLEGSNELKSR
VKAAEEAEAEALAKVNEIQMLFGNVVTDAPAGGEDDYIVLEHVGTPRTFDFEPKDHLDLGESLGLIDVKRGTKVGGARFY
YLTGDGAFLQLGMLNLAAQKARENGFQLMIPPVLVRPEVMSGTGFLGAHSDEIYYLERDDLYLVGTSEVALAGYHQDEII
DLSDGPIKYAGWSSCFRREAGSYGKDTRGILRVHQFDKLEMFVYCKPEEAVAQHQALLNMEREMLAAVEVPYRIIDVAGG
DLGSSAARKFDTEAWIPTQNTYRELTSTSNCTTFQARRLRTRYRDESGKAHTAATLNGTLATTRWLVAILENNQQADGSV
IVPEALRPFVGKEVLEPKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-61 41