Gene Information

Name : DIP2141 (DIP2141)
Accession : NP_940457.1
Strain : Corynebacterium diphtheriae NCTC13129
Genome accession: NC_002935
Putative virulence/resistance : Unknown
Product : UDP-glucose 6-dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1004
EC number : -
Position : 2207481 - 2208686 bp
Length : 1206 bp
Strand : -
Note : Similar to Streptomyces coelicolor UDP-glucose 6-dehydrogenase SCBAC19G2.07 TR:CAC44517 (EMBL:AL596138) (447 aa) fasta scores: E(): 2.8e-33, 40.75% id in 422 aa, and to Pseudomonas aeruginosa UDP-glucose 6-dehydrogenase Udg or pa2022 SW:UDG_PSEAE (O86422)

DNA sequence :
ATGCGGATTGGGGTTTTCGGTGCGGGTTACCTAGGTATTACGCATGCTGCGTGTATGTCGCACCTTGGCCACGAGGTGGT
GGCTGTTGATACTGACGCTGCGCGGGTGGCGGAGTTGTTGGCAGGCCGGTTGCCTATTTCCGAGCCTGGTCTGGCGGATC
TTCTAGCGGCGAATTCGGTTGAGTGGACGGATGATCCGCAGCGTGCGCGCGATTGCGACCTCTATTTTGTGTGCGTGGGA
ACACCGAGCACCGATGGTCCCTCTGCCCAGGCAAGACTGGATGTGAGTGCCGTGGTTGCGGCGGTGGGGACTATTGCTAC
GCTTGCGCCCCACCCGGTGGTGGTGGGCAAGTCGACGGTGCCGGTGGGGACGTCGATACGCTTGTTGCAGCAATTCCCAC
AGATTCGCTTGCTGTGGAATCCTGAGTTTTTGCGCGAAGGTCACGCGGTGGCGGATACGCTGCACCCTGATCGCATTGTG
ATCGGTGGTGCGGATCCGCAGCCGCTTTTGCGTGTTTATGAGGGGATTAACGCCCCCGTGATCACCACTGATCTGGCTAC
GGCGGAGTTGGCAAAGTCGGCGGCTAATGCGTTTTTGGCTACCAAGCTCAGTTTTATTAATGGGCTGTCGGAACTGGCTA
GTGCCACCGGTGCGGATATTGGCACCATTACTCGGGCCATGGGGCTTGATCCCCGAATCGGCTCCCAGTATTTGTCCGCA
GGCTTGGGCTATGGCGGCGGTTGTTTGCCTAAGGACGTCCGTGGGCTTGCGGCCAGCGCTCGCGATTATCAGGCATCGCA
TTTTGCTGAGCTGTTGAGCATTATCGACGCCACCAATCTGCGGCAGCGCGAGCGCACCTGTGAACTCGTGGCCAACCTGT
GCACCCCAGGCGCGCGGATCGATGTATGGGGTGCCACGTTTAAAGAAGGTTCCGATGATGTGCGCGACTCCCCAGGGTTA
GCTGTGGCCCATGCGTTGAAAACTGCGGGTTTTCGTGTGCGCGTGGTGGATCCCCTCGTGGGGCATTGGCCGCCTGAACT
GCAAGAACCTGAGGCAATTGTGGTGGCAACGGCGTGGTCGGAGTTTAGTCGCGTTGTCCCTGAACCCCGCCTTGCGCATG
GATGTGGCGGTGTGGTGGTGGACGCGCGAGGTGTTTTGAACCGCTCGGCGTGGGTGGCCGCGGGGTGGACGTACAGGAAT
CTCTAA

Protein sequence :
MRIGVFGAGYLGITHAACMSHLGHEVVAVDTDAARVAELLAGRLPISEPGLADLLAANSVEWTDDPQRARDCDLYFVCVG
TPSTDGPSAQARLDVSAVVAAVGTIATLAPHPVVVGKSTVPVGTSIRLLQQFPQIRLLWNPEFLREGHAVADTLHPDRIV
IGGADPQPLLRVYEGINAPVITTDLATAELAKSAANAFLATKLSFINGLSELASATGADIGTITRAMGLDPRIGSQYLSA
GLGYGGGCLPKDVRGLAASARDYQASHFAELLSIIDATNLRQRERTCELVANLCTPGARIDVWGATFKEGSDDVRDSPGL
AVAHALKTAGFRVRVVDPLVGHWPPELQEPEAIVVATAWSEFSRVVPEPRLAHGCGGVVVDARGVLNRSAWVAAGWTYRN
L

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
udgA YP_005682185.1 UDP-glucose 6-dehydrogenase Not tested PiCp 7 Protein 1e-51 45
udgA YP_003784334.1 UDP-glucose 6-dehydrogenase Not tested PiCp 7 Protein 1e-51 45
udgA YP_005686369.1 UDP-glucose 6-dehydrogenase Not tested PiCp 7 Protein 1e-51 45