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Name : lysS (DIP2138) Accession : NP_940454.1 Strain : Corynebacterium diphtheriae NCTC13129 Genome accession: NC_002935 Putative virulence/resistance : Unknown Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 2202940 - 2206089 bp Length : 3150 bp Strand : + Note : catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA DNA sequence : ATGCATAAACGTTGGGAATCTCGCCTCTTATTATGGACGGCACAGGTATCCACCATCTGGATGGTGGTGGGCCTTGTGCT CAAGTACATCAATTGGGATCTCACCGAGTCGATCGCGACGGCGTTCTCGGTATTTAACCTGCCGAGTTATCCCTCGTTGT TCATTGCCATCTTGATGGTGCTGCTGACCTCCGGCTTATTGCGTGGTAATCGTGGCGCGCTGGTGTTTTATCTCCTTGGT TTCCAGGTGCCCTCGCTACTGATTGGCATTGCGTACCTGCTCATCGTTGTTTTTGATGCCGAAGAAACACTGGATGTCTT TTCGCTTCTGGTACTTATCTCCACTGCAGCTTCGGTGCTGTTCTTGGTGGCAGGTTGGCGTGCCCGCGACGAGTTCCCCG CCCGTGTCGAGGGCTCGTGGGTAAAGGCACTGGTGGTGTTGGGGGGCGGCATTGCGGTGTCGTTTAGCATCGTCTTGTCG CTTTTGGTGGTCTACTATCACAAGCCGATTGATTTGTCGGCAGTGTGGGCAATGTATACCGCTCTTGGTGTGAGCCCGAA CCAACCGCCGTTTGCTGCGGGTATTCATGCCCCGCACTATCTCAAGGTGCTGGGTTCTGTGTTGTCCTCGGCTGCTATTT TTCTTGCGTTGGCTGTGATGATGCGTTCGCGTAAGTTCTATCGCGCCAGCGCCGAGGATCACCTGTTGTTGCGTAAGTTG TTGTTGTCACCGCCGTCCTCGGATTCGTTGGCGTATTTTGCCACGCGTGATGATCGCAACCTTGTGGTGTCGCCTAATGG TGCTGCTGCGATTTCTTATCGTGTGATTGATGGGGTGTGTTTGGCTGCAGGCGATCCGATTGGTGATCCAGCTTGCTGGC CTGCTGCGATGTCCGCATGGCGTACCGAGGCAAGGAAGAATGGCTGGATTCTCGGTGTTGCTTCGGCCTCGGAGAAGGGT GCGCGTGCCTACGCTGAGATGGGTCTGCGAGTTATTCCCCTAGGCGATGAGGCGATCATTGATGCTGAGCATTTCCGGTT GAAGGATCTTCCAGCGGTTCGTAAAGAAATCGCTGGTCCACGCAAGGCTGGCTATACCGTCAAGGTGGTGCGCCAGGAGC AGCTCACCGCCGAGGAAGCCGCCCATTATGCGGAGGTAGCGCAGCAGTGGCGGCGTGGCGACGAGCGTGGTTTTACCATG GCGTCGGGCCGCGTGGGTGATCCTCGTGATCGTCGCACGGTGCTGGTTGCAGCCCATGATTCCACCGGCGAGCCGATGGG CGTGCTCACGTTGGTGCCGTGGGGCCGTAATGGGCTTTCCTTGGATGTGATGCGTCGTAATCCGAAGGCGCTCGGTGGTG TGACTGAGCTGATGGTGGCTGCCCTGGCCGCCGAGGCCCCCAACCTTGGTGTTAGTCGTTTCTCCTTGAACTTTGTGACC TTCCGCGAGTCCCTCGACCGCGGCATGGCGGTCGGGGCGTCCCCATGGGAGCGGCTGCTATTTAAGCTGTTGGTCACCTC CTCGCGGTGGTGGCAGATCCAGTCGTTGTACCAGTCGAATGTGAAGTATGAGCCCTCGTGGCAGGCGCGTTATCTGTGCA TTGAGCATGGCTTCCACACCCCACGCGTGCTGATTGCGTTCGCTTCGGGTGAGGGATTCTTACCTAGTTTCAATCCATCG TTGGAGCCGCTGGGTGACCCTGAGGCTATCGCCGCGGTGGAGGCCGAAGCATTAACACCGAAGGTGCTGCCACCTCATCG TTCGGCGCAGCAAAAAGCGCGGTTGTGCAAGCTCGATGCGTTGGAGCACAGTGGTATGCGCGCGTATCCGCCAGCTGTTC CACGCGGCGAGGATTCTTTGACGGGCCGTATTTGGTTTATTCGCAACCACGGCCAGGTGTTGTTCGCCGATGTGGTAGAG GGGGAACGTCGTACTCAGTTGCTTATCGACGCCACCACTCCCGACGCACTAGCATCCTTTAAACGCTTAGTGAGCCGTGG CGACATTATTTCTGCCACCGGTGTGATGGGACAGTCGCGCAATGGCACACCGTCGCTGCTTGTGCAGTCGTGGACGATGG CGGCAAAGTCTCTGGTTCCGATGCCTCGCCAGGCATCGCGTAACCCGCATACCCGCGCGAAGTTCCGCCACATTGATTTC ACTATGAATTCGCAGGCACGCTCGATTTTCTCAGCGCGTTCTCGTGCCATCACCGCGGTGCGCTCGGTGCTGGTGTCGCA AGGCTACCTTGAGGCAGAAACCCCTATTTTGCAGACGATCCACGGTGGCGCCAATGCCCGCCCCTTTAGGACTCACATCC GTGCTTATGATCAGCCCCTGACCTTGCGTATCGCCCCCGAGCTGTATCTCAAGCGTTTGGTCGTGGGCGGGTTTGAACGA GTTTTTGAGATGGGCCGAAACTTCCGCAACGAGGGCGTGGATGCTACCCACAACCCAGAGTTCACCTCCTTGGAGGCCTA CCAGGCGTACGGCAACTGGGACACTATGCGGGAGCTAACAGAGAACATCATCCGTTCGGCAGCGATCGCAGTCCACGGTT CCCCACAGGTAACCACTGCTTCTGGCGAGGTTCTTGACCTTTCAGGTTCGTGGCCAGTGGTTCCTGTGTATGAGGCGGTA TCGCGTGCGGTGGGTGAAACAATTTCACCTTCCGGATCACTCGCAGACTACGCGCACATCGCTCAGCGTTACGACATCGA AGCGACCACCGTTGGCGACTTAGTCAACGAGCTTTACGACGAACTGGTCGAACCCACCACAGTATTCCCCACCTTCTACG CTGGTTTCCCCGTAGAAACATCCCCATTGACCATGGCCGACCCCGACGAACCACGCATTGCGCAGCGCTGGGACCTGGTG GCCTGTGGCATGGAGCTCGGAACCGCCTACACCGAGCTTGCCGACCCCATCGAGCAACGCGCGCGCCTCACCGACCAGTC ACTTCGTGCCGCCGGCGGTGACGCCGAAGCCATGGAACTCGACGAGAACTTCCTGCAGGCACTGGAATTTGGCATGCCTC CAACCGGTGGACTCGGAATTGGTATCGACCGCCTCGTCATGTTCCTCACCGGCCAAAACATCCGCGAGGTGCTGGCTTTC CCCTTTGTTAAACCAGACAGCACCAACTAG Protein sequence : MHKRWESRLLLWTAQVSTIWMVVGLVLKYINWDLTESIATAFSVFNLPSYPSLFIAILMVLLTSGLLRGNRGALVFYLLG FQVPSLLIGIAYLLIVVFDAEETLDVFSLLVLISTAASVLFLVAGWRARDEFPARVEGSWVKALVVLGGGIAVSFSIVLS LLVVYYHKPIDLSAVWAMYTALGVSPNQPPFAAGIHAPHYLKVLGSVLSSAAIFLALAVMMRSRKFYRASAEDHLLLRKL LLSPPSSDSLAYFATRDDRNLVVSPNGAAAISYRVIDGVCLAAGDPIGDPACWPAAMSAWRTEARKNGWILGVASASEKG ARAYAEMGLRVIPLGDEAIIDAEHFRLKDLPAVRKEIAGPRKAGYTVKVVRQEQLTAEEAAHYAEVAQQWRRGDERGFTM ASGRVGDPRDRRTVLVAAHDSTGEPMGVLTLVPWGRNGLSLDVMRRNPKALGGVTELMVAALAAEAPNLGVSRFSLNFVT FRESLDRGMAVGASPWERLLFKLLVTSSRWWQIQSLYQSNVKYEPSWQARYLCIEHGFHTPRVLIAFASGEGFLPSFNPS LEPLGDPEAIAAVEAEALTPKVLPPHRSAQQKARLCKLDALEHSGMRAYPPAVPRGEDSLTGRIWFIRNHGQVLFADVVE GERRTQLLIDATTPDALASFKRLVSRGDIISATGVMGQSRNGTPSLLVQSWTMAAKSLVPMPRQASRNPHTRAKFRHIDF TMNSQARSIFSARSRAITAVRSVLVSQGYLEAETPILQTIHGGANARPFRTHIRAYDQPLTLRIAPELYLKRLVVGGFER VFEMGRNFRNEGVDATHNPEFTSLEAYQAYGNWDTMRELTENIIRSAAIAVHGSPQVTTASGEVLDLSGSWPVVPVYEAV SRAVGETISPSGSLADYAHIAQRYDIEATTVGDLVNELYDELVEPTTVFPTFYAGFPVETSPLTMADPDEPRIAQRWDLV ACGMELGTAYTELADPIEQRARLTDQSLRAAGGDAEAMELDENFLQALEFGMPPTGGLGIGIDRLVMFLTGQNIREVLAF PFVKPDSTN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| lysS1 | YP_005682181.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 0.0 | 66 |
| lysS1 | YP_005684273.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 0.0 | 66 |
| lysX | YP_003784331.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 0.0 | 66 |
| lysS1 | YP_005686365.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 0.0 | 66 |
