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Name : DIP2115 (DIP2115) Accession : NP_940431.1 Strain : Corynebacterium diphtheriae NCTC13129 Genome accession: NC_002935 Putative virulence/resistance : Virulence Product : aldehyde dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : - Position : 2164963 - 2166483 bp Length : 1521 bp Strand : - Note : Similar to many eg. Acinetobacter spM-1. aldehyde dehydrogenase 1 Ald1 TR:Q9FDS1 (EMBL:AB042203) (503 aa) fasta scores: E(): 2.5e-143, 69.18% id in 503 aa, and to Alcaligenes eutrophus acetaldehyde dehydrogenase II AcoD SW:DHA2_ALCEU (P46368) (506 aa) fas DNA sequence : ATGACTGTTTATGCATATCCAGGAACGCCAGGTGCTGTAGCCAACTACAAGAAGCGCTATGACAACTACATCGGCGGCCA ATGGGTTCCGCCGGTAGGTGGCGAGTACCTCGACAACATCACCCCAGTCACCGGTGAAGTGTTCTGTCAAGTGGCACGAG GAACCGCTGCCGACGTGGAAAAGGCCTTGGATGCAGCGCATGATGCAGCAAAAACATGGGGTCATAGCTCGCCGGCTGAG CGCGCACTCATTCTGCATCGCATTGCCGATCGCATGGAAGAGCATCTCGAAGAAATCGCCGTTGCCGAAACATGGGATAA CGGCAAGGCGGTACGTGAAACTCTCGCCGCCGATATTCCACTGGCCATCGACCACTTCCGCTACTTTGCCGGTGCAATCC GTGCCCAAGAATCGCGAACCTCACAGATCGACCACAACACGGTGGCCTACCACTTCCATGAGCCCATCGGCGTAGTCGGT CAGATCATTCCGTGGAACTTTCCACTGCTCATGGCCGCATGGAAGATCGCCCCAGCTCTTGCTGCGGGTAACACGATTGT GTTGAAGCCCGCGGAGCAAACTCCTGCGTCCATCCTGTTCTGGATCGACATTGTGGGTGACTTGCTTCCTGACGGTGTGC TCAACATCGTCAACGGCCTCGGCGAGGAGGCTGGCGTGGCGCTATCCTCTTCCAACCGCATTGGCAAGATTGCCTTTACT GGTTCCACGCAGGTGGGCAAGATTATCAACCGTGCTGCCGCTGACAAGATCATCCCCGTCACCTTGGAGCTAGGCGGTAA GTCGCCGTCGATCTTCTTCGCGGACATCATGGATTACGACGACCCCTTCCGTGAGAAGTGCATTGAGGGCCTTGCCATGT TCGCACTCAATCAGGGTGAGGTATGTACCTGCCCGTCGCGTGCGTTGGTGCATGAGTCCATCGCGGACGAGTTCCTTGAG CTGGGTGTCCAACGTGTGAAGAACATCAAGCTCGGCAACCCGCTGGACACGGAAACCATGATGGGTGCCCAAGCCTCCAT GGAACAAATGGATAAGATCAGTGGCTACCTCGATATTGGCCCGAAGGAGGGCGCTGAGGTGCTCACCGGTGGCCACGTGA ACAAGATTGACGGTTTGGAAAATGGCTACTATATCGAGCCCACGGTGTTTAAGGGCACGAATGACATGACCATTTTCCGT GAGGAAATCTTCGGCCCAGTGCTTTCGGTTGCTACCTTCAAGGATTTTGATGAGGCAATCCGCATTGCTAATGACACTAA CTATGGCTTGGGCGCTGGTGTGTGGACTCGCCATCAGAACACTGCGTATCGTGCCGGACGTGCCATCCAAGCTGGTCGCG TGTGGGTGAATCAATACCATAATTACCCAGCGCACGCAGCATTCGGAGGCTATAAGGAGTCTGGAATTGGGCGTGAGAAT CACCTCATGATGTTGGATCACTACCAGCAGACAAAGAACCTTCTTGTCTCGTATGATGAGAATCCAACAGGCTTATTTTA A Protein sequence : MTVYAYPGTPGAVANYKKRYDNYIGGQWVPPVGGEYLDNITPVTGEVFCQVARGTAADVEKALDAAHDAAKTWGHSSPAE RALILHRIADRMEEHLEEIAVAETWDNGKAVRETLAADIPLAIDHFRYFAGAIRAQESRTSQIDHNTVAYHFHEPIGVVG QIIPWNFPLLMAAWKIAPALAAGNTIVLKPAEQTPASILFWIDIVGDLLPDGVLNIVNGLGEEAGVALSSSNRIGKIAFT GSTQVGKIINRAAADKIIPVTLELGGKSPSIFFADIMDYDDPFREKCIEGLAMFALNQGEVCTCPSRALVHESIADEFLE LGVQRVKNIKLGNPLDTETMMGAQASMEQMDKISGYLDIGPKEGAEVLTGGHVNKIDGLENGYYIEPTVFKGTNDMTIFR EEIFGPVLSVATFKDFDEAIRIANDTNYGLGAGVWTRHQNTAYRAGRAIQAGRVWVNQYHNYPAHAAFGGYKESGIGREN HLMMLDHYQQTKNLLVSYDENPTGLF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 6e-147 | 63 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 3e-155 | 62 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 3e-155 | 62 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 3e-155 | 62 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 7e-155 | 62 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| DIP2115 | NP_940431.1 | aldehyde dehydrogenase | VFG0082 | Protein | 3e-147 | 63 |
