Gene Information

Name : nrdE (DIP1867)
Accession : NP_940204.1
Strain : Corynebacterium diphtheriae NCTC13129
Genome accession: NC_002935
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 1911340 - 1913499 bp
Length : 2160 bp
Strand : -
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
GTGAATCAATCCATGGGAAGGCACGTCGCTGAGCCAGTTTCCCGCGCTGAGCAACTCGACTACCACGCACTGAATGCACT
GTTGAACCTTTATGACGCAAACGGGCGAATCCAATTTGATAAAGACCGCGAAGCGGCCAACCAGTTCTTCCTGCAGCACG
TCAATCAAAACACAGTGTTCTTCCACGACCTAGAAGAAAAGATCGAATACCTCGTAGAAAACAACTACTACGAGCCAGAA
GTGCTGGACAAGTACTCTTTTGCAGGCATCAAAGACCTGTTCAAGCAGGCCTACGCGCATAAGTTCCGCTTCAAGTCATT
CTTGGGTGCCTACAAGTACTACACCTCGTACACGCTCAAAACCTTCGACGGTCGACGCTACCTCGAGCGCTTCGAAGATC
GCGTGTGCATGGTGGCACTAACGCTTGCCGACGGATCCATCGAGCTGGCTCGTAACCTCGTTGACGAGATCATGACCGGA
CGTTTCCAGCCGGCAACCCCGACCTTCCTTAACTCCGGTAAGGCACAGCGCGGCGAACCAGTATCGTGCTTCTTGTTGCG
TATCGAAGACAACATGGAGTCGATCGGACGTTCCATTAACTCCGCATTGCAGCTGTCCAAGCGTGGTGGTGGCGTGGCGT
TGCTGCTGAGCAACCTGCGTGAATCCGGTGCACCGATCAAGAAGATTGAGAACCAGTCTTCCGGTGTTATCCCTGTGATG
AAGCTGCTCGAGGATTCCTTCTCCTACGCTAACCAGCTGGGCGCACGTCAAGGTGCAGGTGCGGTGTACCTGAATGCTCA
CCACCCAGACATCTTGAACTTCCTGGACACCAAGCGCGAAAATGCCGATGAGAAGATCCGCATTAAGACATTGTCGCTGG
GCATTGTGATCCCAGACATCACCTTTGAGCTGGCTAAGCGAAACGAAGACATGTATCTGTTTAGCCCCTACGACGTCGAG
CGCGTCTACGGTAAGCCATTTGCGGATATCTCTGTCACCGAACTCTATGCCGACATGGTCGAAGATCCGCGTATCCGCAA
GACCAAGATCAACGCCCGTTCGTTCTTCCAAACGATCGCCGAGATCCAGTTCGAGTCCGGTTACCCGTACATCATGTTCG
AAGATACCGTTAACCGCGCCAACCCCATCGAAGGCCGGATTAACATGTCTAACCTGTGCTCGGAGATCCTGCAGGTCAAC
TCGCCATCAGTTCTTAATGCTGATCTGACCTACGAGCATGTCGGCGAAGACATCTCGTGCAACCTTGGCTCCATGAACAT
CGCTATGGCCATGGATTCCACTGACTTTGCTAAGACCGTGGAAACCGCGATTCGTGGTTTGACCGCGGTGTCCGAGCAGA
CCTCCATCGATTCCGTGCCATCCATTAAGAAGGGCAACGATGCAGCTCATGCCATCGGCCTTGGCCAGATGAACCTGCAC
GGCTACTTGGGTCGTGAGCATATCTTCTACGGATCAGAAGAAGGCTTGGACTTTACCAACGCCTACTTTGCCGCCGTGTT
GTATCAATGCCTGCGCGCTTCTCACAAGATTGCTGCGGAACGCGGCCAGCGTTTTGAAGGCTTTGAAACTTCCGACTATG
CCGATGGCAGCTACTTTGATCGTTTCGATCCAGCTGACTTTGCGCCGAAGACCGCAAAGGTTCAAGAGCTATTTGAAAAC
TCCACCATTGTTGTGCCTACTGCAGAGGACTGGGAAGAGCTCAAGCAGTTGGTCATGAAGGACGGCTTGTTTAACCGCTA
CCTTCAGGCTGTGCCTCCGACGGGTTCGATCTCGTACATCAACAACTCCACCTCGTCGATTCACCCGATCGCCTCTCGTA
TTGAGATCCGTAAGGAAGGCAAGATCGGTCGTGTGTACTACCCAGCGCCGCACATGGATAACGACAACTTGGAGTACTAC
CAAGATGCCTATGAGATTGGCTTTGAAAAGGTTATTGATACCTATGCGGTAGCCACCAAGTATGTTGACCAGGGACTTTC
GTTGACGCTGTTCTTCAAGGACAACGTGACAACCCGTGACATCAACCGCGCGCAGATCTACGCATGGCGTAAAGGAATTA
AGTCCCTGTACTATATTCGCCTCCGCCAAGTTGCCCTTGAGGGTACCGAGGTCGAGGGTTGCGTATCCTGCATGCTATAA

Protein sequence :
MNQSMGRHVAEPVSRAEQLDYHALNALLNLYDANGRIQFDKDREAANQFFLQHVNQNTVFFHDLEEKIEYLVENNYYEPE
VLDKYSFAGIKDLFKQAYAHKFRFKSFLGAYKYYTSYTLKTFDGRRYLERFEDRVCMVALTLADGSIELARNLVDEIMTG
RFQPATPTFLNSGKAQRGEPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLSNLRESGAPIKKIENQSSGVIPVM
KLLEDSFSYANQLGARQGAGAVYLNAHHPDILNFLDTKRENADEKIRIKTLSLGIVIPDITFELAKRNEDMYLFSPYDVE
RVYGKPFADISVTELYADMVEDPRIRKTKINARSFFQTIAEIQFESGYPYIMFEDTVNRANPIEGRINMSNLCSEILQVN
SPSVLNADLTYEHVGEDISCNLGSMNIAMAMDSTDFAKTVETAIRGLTAVSEQTSIDSVPSIKKGNDAAHAIGLGQMNLH
GYLGREHIFYGSEEGLDFTNAYFAAVLYQCLRASHKIAAERGQRFEGFETSDYADGSYFDRFDPADFAPKTAKVQELFEN
STIVVPTAEDWEELKQLVMKDGLFNRYLQAVPPTGSISYINNSTSSIHPIASRIEIRKEGKIGRVYYPAPHMDNDNLEYY
QDAYEIGFEKVIDTYAVATKYVDQGLSLTLFFKDNVTTRDINRAQIYAWRKGIKSLYYIRLRQVALEGTEVEGCVSCML

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 83