Gene Information

Name : rph (DIP1851)
Accession : NP_940188.1
Strain : Corynebacterium diphtheriae NCTC13129
Genome accession: NC_002935
Putative virulence/resistance : Unknown
Product : ribonuclease PH
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0689
EC number : 2.7.7.56
Position : 1895536 - 1896261 bp
Length : 726 bp
Strand : -
Note : RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs

DNA sequence :
ATGACTGATTTTTCTCGTGCAGACGGCCGCGCCGTCGACCAGATGCGTACTGTTAAAATCACCCGCGGTTTTACCTCAAA
CCCAGCCGGCAGCGTTCTCGTTGAATTCGGCAACACTCGCGTGATGTGTACCGCCTCCGTTGAACTCGGTGTTCCTCGCT
TCAAGCGTGACTCCGGCGAAGGTTGGCTCACCGCCGAATACGCCATGCTGCCTGCTGCAACCGCTGAGCGCAATGCTCGC
GAGTCCATGCGCGGCAAGGTGAAGGGCCGCACCCATGAGATTTCTCGTCTGATTGGGCGCTCTCTGCGTGCCGCTGTTGA
CCTTGACGAGCTTGGTGAAAACACCATCAACATCGACTGCGACGTTTTGCAGGCCGACGGTGGCACCCGCACCGCTTCGA
TCACCGGCGCATACGTGGCCCTTGCCGACGCCATCGCTGTGCTCAAAGAACAAGGCGTAGTCCCCGGTAATCCTCTGAAA
GCAGCAGTAGCTGCGGTGTCTGTCGGCGTGATCGATGGTCAAGTGTGCCTCGACTTGCCCTATGAGGAAGATTCCCGCGC
AGATGTGGACATGAACGTGATCATGCAGGGCGATCGCTTTGTGGAAATCCAGGGCACCGGTGAGCACAACACCTTTGATC
GTGATGAGCTTGCCGTCATCTTGGACTTCGCGCAGAAGGGCTGCCAAGAACTGTTCGCCGCACAGAAGGCAGCTCTAGAA
CAGTGA

Protein sequence :
MTDFSRADGRAVDQMRTVKITRGFTSNPAGSVLVEFGNTRVMCTASVELGVPRFKRDSGEGWLTAEYAMLPAATAERNAR
ESMRGKVKGRTHEISRLIGRSLRAAVDLDELGENTINIDCDVLQADGGTRTASITGAYVALADAIAVLKEQGVVPGNPLK
AAVAAVSVGVIDGQVCLDLPYEEDSRADVDMNVIMQGDRFVEIQGTGEHNTFDRDELAVILDFAQKGCQELFAAQKAALE
Q

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
rph YP_001800860.1 ribonuclease PH Not tested Not named Protein 1e-87 79