Gene Information

Name : glnA1 (DIP1644)
Accession : NP_939986.1
Strain : Corynebacterium diphtheriae NCTC13129
Genome accession: NC_002935
Putative virulence/resistance : Virulence
Product : glutamine synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0174
EC number : 6.3.1.2
Position : 1678597 - 1680033 bp
Length : 1437 bp
Strand : +
Note : Similar to Corynebacterium glutamicum glutamine synthetase I GlnA TR:O32354 (EMBL:Y13221) (477 aa) fasta scores: E(): 6.8e-157, 79.49% id in 478 aa, and to Streptomyces coelicolor glutamine synthetase GlnA or SC3H12.06 SW:GLNA_STRCO (P15106) (469 aa) fast

DNA sequence :
GTGGCTTTTACTTCCACCGAAGACGTCATTAAGTACATCAAAGAAGAAAACGTCGAGTTTCTTGATATTCGCTTCACCGA
CGTTCCGGGCCGTGAACAGCGCATCACCATCCCTGCATCGATGTTCACCGAGGAAGCTGCTGAAGATGGCTTCGCATTCG
ATGGTTCCTCCATCCGAGGATTTACCACCATCGATGAATCCGACATGAACTTGCACCCCGACATTGCTACCGCAATGGTC
GACCCATTCCGCAAGGCTAAGACACTGAACATGAAGTTCTTTGTCCACGACCCATTCACCCGCGAGCCATTCTCCCGTGA
CCCACGTAACGTTGCCCGCAAAGCCGAGCAGTACCTGGCTTCTACCGGCATTGCTGACACCTGTTTCTTCGGCGCAGAAG
CTGAATTCTACGTCTTTGACAAAGTCAGCTACGAAATTGAAGGCAACCGCTCCCACTACGAAGTCGACTCCGACAACGGT
TGGTGGAACCGCGGCGTAGACCAAAACCTCGATGGCACCCATAACCGCGGCTATAAGACCCCATTCAAAGGCGGCTACGG
CCAGTGCGCACCATACGACACCCTCGAAGATCTTCGCGACGAGATGACACTCACCTTGCGCGACGCAGGCTTTGACATTG
AGCGCCAGCACCCAGAATGCGGTACCGGATCACAGCAAGAGATCAACTACCGATTCAACACCCTGCTCCACGCTGCCGAT
GATCTACAGACCTTCAAGTACATCATCAAAAACACCGCTTTCCGCAACGGCAAGACCGCAACGTTTATGCCTAAGCCACT
GGCAGGCGACAACGGCTCCGGCATGCACGCCCACCAGTCACTGTGGAAGGACGGCAAGCCACTGTTCCACGATGAGGTCG
GCTACGCAGGCCTTTCCGACATGGCCCGCTACTACATCGGTGGTATTCTGCACCACGCAGGCGCAGTTTTGGCGTTTACC
AACCCAACGCTTAACTCCTACCATCGCCTAGTCCCTGGCTTCGAGGCTCCCATTAACCTCGTGTACTCCCAGCGTAACCG
CTCGGCTGCGATCCGCATTCCGATCACCGGCTCCAACCCAAAGGCAAAACGCATCGAATTCCGCGCACCAGACCCATCAG
GCAACCCATACTTCGGTTTCGCTGCCATGATGCTCGCAGGCCTCGATGGCATCAAGAACCGCATCGAGCCACACGCTCCC
GTGGATAAGGATCTCTACGAGCTACCACCAGAGGAAGCCGCTTCCATCCCTCAGGCACCAACCTCCCTCGAGGCATCCCT
GAAGGCTTTGGAGGAGGACAACGAGTTCCTCACCGACGGCGATGTCTTCACCGACGACTTGATCGACGCCTACATCAAGC
TCAAGTACGATAATGAAATTGCACCTGTTCGCCTGCGCCCAACCCCGCAGGAGTTCGAGATGTACTTCGACTGCTAA

Protein sequence :
MAFTSTEDVIKYIKEENVEFLDIRFTDVPGREQRITIPASMFTEEAAEDGFAFDGSSIRGFTTIDESDMNLHPDIATAMV
DPFRKAKTLNMKFFVHDPFTREPFSRDPRNVARKAEQYLASTGIADTCFFGAEAEFYVFDKVSYEIEGNRSHYEVDSDNG
WWNRGVDQNLDGTHNRGYKTPFKGGYGQCAPYDTLEDLRDEMTLTLRDAGFDIERQHPECGTGSQQEINYRFNTLLHAAD
DLQTFKYIIKNTAFRNGKTATFMPKPLAGDNGSGMHAHQSLWKDGKPLFHDEVGYAGLSDMARYYIGGILHHAGAVLAFT
NPTLNSYHRLVPGFEAPINLVYSQRNRSAAIRIPITGSNPKAKRIEFRAPDPSGNPYFGFAAMMLAGLDGIKNRIEPHAP
VDKDLYELPPEEAASIPQAPTSLEASLKALEEDNEFLTDGDVFTDDLIDAYIKLKYDNEIAPVRLRPTPQEFEMYFDC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 7e-86 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA1 NP_939986.1 glutamine synthetase VFG1399 Protein 1e-152 68