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Name : tkt (DIP1302) Accession : NP_939655.1 Strain : Corynebacterium diphtheriae NCTC13129 Genome accession: NC_002935 Putative virulence/resistance : Unknown Product : transketolase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : 2.2.1.1 Position : 1311649 - 1313751 bp Length : 2103 bp Strand : + Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo DNA sequence : GTGACTTTATCTCCGGAGCTTCAGGCTCTTACCTCCCGTCACTACCCTAGCGACTGGGACGACCTCGATACTCAGGCAGT TGACACAGCACGTGTACTCGCTGCCGATGCAGTCCAGAATTGCGGTTCGGGCCACCCAGGCACTGCAATGAGCTTGGCAC CTCTGGCTTACACTCTTTTCCAACGTGTCATGAATGTCGATCCTGCGGATCCGCATTGGGCTGGTCGCGATCGTTTTGTG TTGTCATGTGGGCACACTTCACTTACGCAATACATCCAGCTTTACTTCGGCGGTTACGGCCTCGAACTTGAAGACCTTAA AGCCCTGCGTACTTGGGGCGCATTAACTCCTGGCCACCCAGAATACCGCCATACTAAAGGCGTTGAAATCACAACTGGCC CATTGGGTCAAGGCTTGGCATCGGCTGTTGGCATGGCGATGGCCTCACGACGTGAGCGCGCGTTGTTCGATCCCACTGCG GCAGATGGTGCATCTCCATTCGACCACTATATTTATGTGATTGCTTCTGATGGCGACCTTCAGGAAGGTGTCACTGCGGA GGCATGTTCGCTTGCCGGAACTCAAAAGCTTGGAAATCTCATCGTTTTCTGGGATGATAACCGGATCTCGATCGAAGAAG ATACTGAGATTGCATTCAACGAAAAGGTTGTCGATCGTTACCGTGCTTATAACTGGCAAGTAATCGAAATTGACGGCGGC GAAAACGTTGAAGCGATTGAAAAGGCAGTCGCAGAGGCTAAAGCCGATACTTCTCGTCCTACTTTTATCCGCGTACGTAC CGTTATTGGCTATCCTGCGCCAACAAAGATGAATACCGGTGCTGTGCATGGTGCTGCTCTTGGTGCTGAAGAAGTCGCCG GAACTAAGAAAGCACTCGGTTTTAATCCTGAGGAATCCTTCGCGGTAGCTCCGGAGGTCATTTCTCATACACGGAAACTT CTAGAGCGAGGTGCTCAACGACATGCTGAGTGGCGTGAGCATTTCGAATCTTGGGCGGAAACAAACCCCGAAAATAAAGC CCTCTTTGACCGGATGGCTTCCCGCGAACTTCCAGATGGTTTCGATGCTGATCTACCTTCGTGGGAGCCTGATGCCAAAG GCGTCGCAACCCGCAAGGCTTCTGAAGCTACGTTACAGGCACTCGGTGCAACGCTTCCGGAGCTGTGGGGCGGTTCTGCC GACCTAGCAGGCTCGAACAACACTGTTATTAAGGGTTCTCCATCGTTTGGTCCATCTACGATTTCTACGTCCACATGGAC TGCTGAGCCAGGTGGACGTAATCTCCATTTCGGTATCCGCGAACATGCCATGGGCGCAATTATCAATGGCATTTCTCTCC ACGGTGGAACCCGTCCTTATGGTGGAACCTTCCTGATTTTCTCGGATTACATGCGCCCTGCTGTTCGTCTGGCTGCCTTG ATGGGAACCGACGCATACTATGTTTGGACACACGATTCCATCGGATTAGGCGAAGACGGCCCTACTCATCAACCTGTCGA GCAGCTTGCATCGCTGCGTGCTATTCCTGGTGTTTCGATGCTTCGTCCCGCTGATGCTAACGAAACTGCTGCGGCTTGGC GTGCGGCACTCCTGTATAAGGAAGGTCCTAAAGGTCTAGCCCTTACACGTCAAAACGTCCTTGTTCTCGAAGGAACAAAA GAAAAAGCGCGGGATGGTGTCTCACGAGGGGCATATGTTCTCGTTGAAGGATCTAAGAAAACTCCTGACGTTATTTTGAT GGCTTCAGGCTCCGAAGTACAGCTTGCAGTCGAAGCGGCTAAAACTTTGGAAGCAGAAAAGATTGCAGCTCGAGTCGTGT CTGTGCCTTGCTTAGATTGGTTCGAGGAACAAGACGCCGCTTATCAAGAAGAGATACTTCCGCAGGCGGTTAGCGCTCGC GTATCGGTGGAAGCGGGTGTCGCTTTGTCTTGGTATCGCCATCTGGGCACCCATGGTCGGGCCGTGTCCCTTGAGCACTT CGGCGCATCTGCTCCGTATGAGAAGCTCTTCAGTGAATTTGGCATAACCACTGAAGCAGTTATTGCTGCAGCTCGCGAAT CACTTGCTGCTGCTCAGCAATAA Protein sequence : MTLSPELQALTSRHYPSDWDDLDTQAVDTARVLAADAVQNCGSGHPGTAMSLAPLAYTLFQRVMNVDPADPHWAGRDRFV LSCGHTSLTQYIQLYFGGYGLELEDLKALRTWGALTPGHPEYRHTKGVEITTGPLGQGLASAVGMAMASRRERALFDPTA ADGASPFDHYIYVIASDGDLQEGVTAEACSLAGTQKLGNLIVFWDDNRISIEEDTEIAFNEKVVDRYRAYNWQVIEIDGG ENVEAIEKAVAEAKADTSRPTFIRVRTVIGYPAPTKMNTGAVHGAALGAEEVAGTKKALGFNPEESFAVAPEVISHTRKL LERGAQRHAEWREHFESWAETNPENKALFDRMASRELPDGFDADLPSWEPDAKGVATRKASEATLQALGATLPELWGGSA DLAGSNNTVIKGSPSFGPSTISTSTWTAEPGGRNLHFGIREHAMGAIINGISLHGGTRPYGGTFLIFSDYMRPAVRLAAL MGTDAYYVWTHDSIGLGEDGPTHQPVEQLASLRAIPGVSMLRPADANETAAAWRAALLYKEGPKGLALTRQNVLVLEGTK EKARDGVSRGAYVLVEGSKKTPDVILMASGSEVQLAVEAAKTLEAEKIAARVVSVPCLDWFEEQDAAYQEEILPQAVSAR VSVEAGVALSWYRHLGTHGRAVSLEHFGASAPYEKLFSEFGITTEAVIAAARESLAAAQQ |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 6e-120 | 45 |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 7e-117 | 44 |
