Gene Information

Name : DIP1059 (DIP1059)
Accession : NP_939420.1
Strain : Corynebacterium diphtheriae NCTC13129
Genome accession: NC_002935
Putative virulence/resistance : Virulence
Product : iron-siderophore uptake system ATP-binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 1037950 - 1038771 bp
Length : 822 bp
Strand : -
Note : Similar to Streptomyces coelicolor iron-siderophore uptake system ATP-binding component SCI51.25C TR:Q9S215 (EMBL:AL109848) (301 aa) fasta scores: E(): 1.9e-42, 50.58% id in 255 aa, and to Escherichia coli ferric enterobactin transport ATP-binding protein

DNA sequence : 
ATGACCAGCACTTCCCCCATTCTTCGTACCGATTCCGTCACATTGGCGTGGGATAAGCACACAGTAAGTACTGATCTCAC
GGTTGAGGTGCCGCAAGGACAATTCACAGCCATCATTGGGCCAAATGGTTGTGGAAAATCCACACTATTAAAAAGCTTCG
CCCGAATTCTTCAACCACACACTGGGCAAGTATATCTAGGTGACAACCCGCTGGATTCTTTGCACACAAAATACATAGCC
CAACGTATCGCTTTGCTGCCACAAACAGCACTTGCACCAGCTGATATTACTGTCGAAGAACTCGTAGGCAGAGGTCGTTT
CCCCTACCAAACCCTTCTGCGACAGTGGTCAACTAAGGATGCTCAAGCAGTTGATTCCGCCCTCCTAGCAACCGGCACGG
CACAACTACGCCACCGCCGCGTTACTGAACTTTCTGGCGGCCAACGTCAACGAGTCTGGCTCGCAATGGTGCTGGCCCAA
AACACACCCGTAGTTCTCCTAGACGAGCCCACAACGTATCTCGATGTAGCCCACCAATACCAGCTTTTAGAGCTCGCCCG
AGCACTGCGGCAACAGCTCGGACGAACTATTGTGACCGTCTTGCACGATCTACAACAGGCTGTTAGATATGCCGACCATC
TTATTGTGATGAAAGGTGGCGCAGTCTATGCTGAAGGCGCTCCAAGCAGCATCATGACACCACAATTGATTTCCGAGGTA
TTTGACATCAATGTTGATGTTCATACCATCGACGATCATGTGGTGATCGTGCCCAAAACCATGCCTCAACCTGATGTATC
AGTCCTAGAAAATCTGCAATAG

Protein sequence : 
MTSTSPILRTDSVTLAWDKHTVSTDLTVEVPQGQFTAIIGPNGCGKSTLLKSFARILQPHTGQVYLGDNPLDSLHTKYIA
QRIALLPQTALAPADITVEELVGRGRFPYQTLLRQWSTKDAQAVDSALLATGTAQLRHRRVTELSGGQRQRVWLAMVLAQ
NTPVVLLDEPTTYLDVAHQYQLLELARALRQQLGRTIVTVLHDLQQAVRYADHLIVMKGGAVYAEGAPSSIMTPQLISEV
FDINVDVHTIDDHVVIVPKTMPQPDVSVLENLQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 5e-77 65
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 5e-77 65
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 5e-77 65
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 5e-77 65
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 2e-52 52
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 3e-51 46
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 6e-45 41
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 6e-45 41
ciuD YP_003783391.1 iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 2e-42 41
ciuD YP_005685432.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 2e-42 41
ciuD YP_005681255.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 2e-42 41
ciuD YP_005683346.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 2e-42 41
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 8e-38 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
DIP1059 NP_939420.1 iron-siderophore uptake system ATP-binding protein BAC0164 Protein 1e-52 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
DIP1059 NP_939420.1 iron-siderophore uptake system ATP-binding protein VFG1042 Protein 1e-52 52
DIP1059 NP_939420.1 iron-siderophore uptake system ATP-binding protein VFG0925 Protein 6e-57 52