Gene Information

Name : thrA (DIP1036)
Accession : NP_939398.1
Strain : Corynebacterium diphtheriae NCTC13129
Genome accession: NC_002935
Putative virulence/resistance : Unknown
Product : homoserine dehydrogenase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0460
EC number : 1.1.1.3
Position : 1016931 - 1018277 bp
Length : 1347 bp
Strand : +
Note : catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine

DNA sequence :
ATGAACCCTGACTCACAGCATCATGCAACGTTTAACCCTGGCAAAGGTGAAGGATCACCTGTGGGAATCGCGATTTTGGG
CTATGGCACAGTGGGTAGCCAAGTTCTTCGTCTCCTCACCGAGAATCATAATGATTTCCAACATCGCGCCGGTGGACCGC
TTGAGATCAAGGGTGTTGCTGCCTCCAGTGTGGAAAAGCACCGTGGATCTCTTGCCGATCAACTAGGACTACTTACAGAC
GATGCGCGCTCGCTTATTGCTCGTGATGACGTAGATATCGTTGTGGAAGTCATCGGTGGAATCGACTATCCGCGTGAGCT
CATTCTTGAGGCTCTACACAGCGGAAAGTCTGTGGTGACAGCAAACAAGGCGCTGGTCGCGGCTCATTCAGAGGAGCTTG
CTGCTGCAGCTGACGAGGCCGGAGTTGACCTCTACTTCGAGGCCGCAGTTGCCGCTGCAATCCCAGTGCTTGGCCCACTA
CGTCGTTCCTTGGCTGGTGACCAAATCCAGTCGGTTGCCGGCATTGTTAACGGAACGACCAACTTCATCTTGGACGCCAT
GGATTCTACGGGTGCAAGCTATGATGACATGCTCGCAGAAGCCACCCGATTGGGCTATGCAGAAGCAGACCCAACAGCAG
ATGTTGAAGGCCATGACGCAGCATCGAAAGCAGCTATTCTTGCATCCTTGGCATTCCATACACGCGTAACTTATGCGGAT
GTGTACTGTGAGGGAATCTCGAAGATCACGGCAGACGACATCAACGCAGCCAAGGAAGCAGGCTTTACCATCAAACTGCT
TGCTATCTGCGAGCGGCTCAATGTTGATGGCGTAGAAAAGGTTTCTGCGCGCGTTCATCCCACCTTGGTCCCACGCAATC
ACCCCCTGGCCAGCGTAGATAAGTCCTTCAACGCAATTTTCGTTGAAGCTGAAGCTGCAGGCCGACTTATGTTCTATGGC
AATGGTGCTGGTGGTAACCCAACGGCATCGGCGGTGCTCGGCGATATTGTCGGCGCTGCTCGCAACAAGGTTTTTGGTGG
GCGTGCCCCAGGCGAATCCACCTATGCGGATCTTCCCATTGCACCATTCGGTGAGGTCCCTACACGCTTCCATATCGATA
TGGAAGTAGAAGACCGCGTTGGCGTATTGGCGGATCTTGCTAAGACTTTCTCTAACCATGGTATTTCGTTGCGCACTGTG
CGTCAGGCTGAAAAAGATGGTCATGCCCGCTTGATTGTGGTTACGCATACGGCCAAGGAATCGGAACTTGAAGCAACCGT
TGAACAGATTAAGAATTCTGACTCGGTGAAAAAGATCAACAGCGTTATTCGTCTAGCAGGGGAGTAA

Protein sequence :
MNPDSQHHATFNPGKGEGSPVGIAILGYGTVGSQVLRLLTENHNDFQHRAGGPLEIKGVAASSVEKHRGSLADQLGLLTD
DARSLIARDDVDIVVEVIGGIDYPRELILEALHSGKSVVTANKALVAAHSEELAAAADEAGVDLYFEAAVAAAIPVLGPL
RRSLAGDQIQSVAGIVNGTTNFILDAMDSTGASYDDMLAEATRLGYAEADPTADVEGHDAASKAAILASLAFHTRVTYAD
VYCEGISKITADDINAAKEAGFTIKLLAICERLNVDGVEKVSARVHPTLVPRNHPLASVDKSFNAIFVEAEAAGRLMFYG
NGAGGNPTASAVLGDIVGAARNKVFGGRAPGESTYADLPIAPFGEVPTRFHIDMEVEDRVGVLADLAKTFSNHGISLRTV
RQAEKDGHARLIVVTHTAKESELEATVEQIKNSDSVKKINSVIRLAGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00305 YP_008207770.1 Homoserine dehydrogenase Not tested AbaR25 Protein 5e-49 41
BJAB0868_00309 YP_008211635.1 Homoserine dehydrogenase Not tested AbaR26 Protein 5e-49 41