Gene Information

Name : tpx (CT0754)
Accession : NP_661649.1
Strain : Chlorobium tepidum TLS
Genome accession: NC_002932
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 728087 - 728593 bp
Length : 507 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGATTATGGCAACCATTACGCTCAAGGGAAATTCCATTCACACCGCAGGTGAGCTTCCGGCTGTCGGCAGTCAGCTCCC
AGCGTTTACCCTTGTGAAAAGTGATCTTTCGGAGGTTTCGCCTGCTGATTTCGCTGGCAAGAAACTCGTGCTGAACATTT
TTCCGAGTCTCGATACGGCTGTTTGCGCGGCTTCGGTGAGGCGCTTCAACAAGGAGGCGGGCGAGCGTGGTGATGCTGTC
GTGCTCTGCATTTCCGCCGATCTTCCGTTCGCGCAGGGGCGCTTCTGCACCACCGAGGGTCTCGACAATGTGGTTCCCCT
GTCGGTGTACCGTTCACCGGAGTTTGGCTTGGATTATGGCCTGACCATTACCGATGGCCCGCTGAAAGGATTGCTCTCTC
GCGCGGTGATCGTTACCGATGCTTCCGGCAAGGTGCTCTATGCCGAGCAGGTACCCGAGATCGTACAGGAGCCGGATTAC
GACAAGGCTCTGGCTGCGCTCGCCTGA

Protein sequence : 
MIMATITLKGNSIHTAGELPAVGSQLPAFTLVKSDLSEVSPADFAGKKLVLNIFPSLDTAVCAASVRRFNKEAGERGDAV
VLCISADLPFAQGRFCTTEGLDNVVPLSVYRSPEFGLDYGLTITDGPLKGLLSRAVIVTDASGKVLYAEQVPEIVQEPDY
DKALAALA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 8e-37 47
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 7e-37 47
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 5e-37 47
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 5e-37 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx NP_661649.1 thiol peroxidase VFG0087 Protein 2e-37 47