Gene Information

Name : hsdM-1 (CT0675)
Accession : NP_661571.1
Strain : Chlorobium tepidum TLS
Genome accession: NC_002932
Putative virulence/resistance : Unknown
Product : type I restriction system adenine methylase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 666360 - 667955 bp
Length : 1596 bp
Strand : +
Note : identified by match to PFAM protein family HMM PF02384

DNA sequence :
ATGGCAAGATCTGATAGTGACAAGAACGGCAATGGGGGCAACCTCGGCTTCGAGGCTGAACTGTTCAAAGCCGCCGACAA
GCTGCGCGGCAACATGGAGCCCAGCGACTACAAGCACGTCGCGCTGGGTTTGATCTTCCTGAAGTACATCTCCGACGCCT
TCGAGGCCAAGCACAAGGCGCTGCTGGCCGAAGATGCACTGGCCGCCGAGGACAAGGACGAATACCTCGCCGACAACGTG
TTCTGGGTGCCAAAGGAGGCGCGCTGGTCGCACCTGCAAGCCAACGCCAAGCAGCCCACCATCGGCACCCTGATCGACGA
CGCGATGCGCGCCATCGAGAAGGACAACGCATCGCTCAAGGGCGTGCTGCCCAAGGATTACGCCCGCCCTGCGCTCAACA
AGGTGATGCTGGGGGAACTCATCGACCTGATCTCCGGCATTGGCCATCTGCTCCCCTCGCCCTCCGGGAGAGGGGCCGGG
GGTGAGGGGCAATCCTTCGACATCCTCGGGCGCGTCTATGAGTACTTCCTCGGCCAGTTCGCCGGGGCCGAAGGCAAACG
CGGCGGCGAGTTCTACACCCCGCGTTCCGTGGTGCGCGTGCTGGTGGAAATGCTGGAGCCGTACTCCGGCCGCGTGTACG
ACCCCTGCTGCGGTTCAGGCGGGATGTTTGTCCAGTCCGAGAAGTTCGTGCAGGAGCACGGCGGCCGTATTGGCGACATC
GCCATCTACGGCCAGGAATCGAACTACACCGCCTGGCGGCTGGCCAAAATGAACCTGGCCGTGCGCGGCATCGACGCCGA
CATCCGCTGGAACAACGAAGGTAGCTTCCACAAGGACGAACTGCGCGACCTCAAGGCCGACTACATCCTGGCCAACCCGC
CCTTCAACATCTCCGACTGGGGTGGCGATCGCCTGCGTGAAGACGTGCGCTGGCAGTTCGGCGTACCGCCCGTGGGCAAC
GCCAACTACGCCTGGCTCCAGCACATCTACTGGCACCTGGCCCCCAACGGCACGGCGGGCGTGGTGCTGGCCAACGGCTC
CATGAGCTCCAACCAGTCGGGCGAGGGCGAGATTCGCCGCGCCATGCTCGAAGCCGACGCGGTGGATTGCATGGTGGCGC
TGCCCGGGCAGCTCTTTTACTCCACGCAAATCCCCGCCTGCCTGTGGTTTCTGGCCCGCAACAAAAACCCCGCGAATGGC
AAAACCGGGGGGCTGCGCGACCGGCGCGGGCACGTGCTGTTCATCGACGCCCGCAAGATGGGCGTGCTGGTGGACCGCAC
CCGGCGCGAACTCAGCGACGAGGAGATCCAGAAAATCGCCCGCACCTACCACGCCTGGCGCGGCGAACCCGACGCGGGCG
ACTACGCCGACGTGGCGGGCTTCTGCAAATCCGCCACGCTGGACGAAATCCGCAAACACGGCCACGTGCTGACGCCCGGC
CGTTACGTGGGCGCAGCGGAAGTGGAAGACGACGGCGAACCCTTCGAGGAGAAGATGGCGCGGCTGGCGGCGCAGTGGCG
GCAGCAGCGGGACGAGGCGGCGAAGCTCGATGCGGCGATTGAGGCGAACCTCAAAGAACTGGGTTTCTGGGAGTGA

Protein sequence :
MARSDSDKNGNGGNLGFEAELFKAADKLRGNMEPSDYKHVALGLIFLKYISDAFEAKHKALLAEDALAAEDKDEYLADNV
FWVPKEARWSHLQANAKQPTIGTLIDDAMRAIEKDNASLKGVLPKDYARPALNKVMLGELIDLISGIGHLLPSPSGRGAG
GEGQSFDILGRVYEYFLGQFAGAEGKRGGEFYTPRSVVRVLVEMLEPYSGRVYDPCCGSGGMFVQSEKFVQEHGGRIGDI
AIYGQESNYTAWRLAKMNLAVRGIDADIRWNNEGSFHKDELRDLKADYILANPPFNISDWGGDRLREDVRWQFGVPPVGN
ANYAWLQHIYWHLAPNGTAGVVLANGSMSSNQSGEGEIRRAMLEADAVDCMVALPGQLFYSTQIPACLWFLARNKNPANG
KTGGLRDRRGHVLFIDARKMGVLVDRTRRELSDEEIQKIARTYHAWRGEPDAGDYADVAGFCKSATLDEIRKHGHVLTPG
RYVGAAEVEDDGEPFEEKMARLAAQWRQQRDEAAKLDAAIEANLKELGFWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 2e-147 60
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 1e-147 59
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 1e-147 58
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 3e-109 50