Gene Information

Name : guaA (CT0175)
Accession : NP_661081.1
Strain : Chlorobium tepidum TLS
Genome accession: NC_002932
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 182906 - 184456 bp
Length : 1551 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGCAACATCCCTGCAATCGGTCATCGTCCTCGATTTCGGTTCACAGTACACTCAGCTCATCGCACGGCGCATCCGCGA
GATCGGCATCTACTCCGAGATTTTTCCGTACCACACAAAGGCCGAAACCATCCGGGCGCATCAGCCGAAAGCGATCATCC
TCTCCGGCGGCCCGAACAGCGTCTATGACGAAAAAGCATTCATGCCCGACCCGGAGGTGTTCAGCCTCGGCGTGCCGGTG
CTCGGCATCTGCTACGGCCTGCAGGCCATCGCCAAGCACTTCGGCGGCAACGTCGAAAGCTCCTCGAAGCAGGAGTTCGG
ACGCGCCAAGATGCTGGTGAACCACGACGAGAGCGAGAGCCTGCTCTTCCGCGACATCCCCGATTCGGACGTCTGGATGA
GCCATGGCGACAAGGTGACGCAGCTGCCGGAGGGCTTCCGCGTGACGGCGAGCACCGCGAATGCCGAGGTGTGCGCCATC
GAGAGCTTCGGCAGCAAAGCCGCGCTCAAGGTCTATGGCTTGCAGTTTCACCCCGAAGTGCAACACTCGCTCTACGGCAA
GCAGCTGCTCTCGAACTTTTTGATCGACATCGCGGGCATCACGCCGGACTGGTCGCCGAAGAGCTTCATCCAGCACCAGA
TCGAGGAGATCAAGCGGGTTGCGGGCGACTCGACCGTGGTGTGCGGCATCAGCGGCGGCGTCGATTCCACGGTGGCCGCC
GTGCTCGTCAGCAAGGCGATCGGCGACAAGCTGCACTGCGTCTTTGTTGACAACGGCCTGCTCCGCAAGGATGAAGCGGT
GAAGGTGATGGAGTTCCTCAAGCCGCTCGGTCTGAACATTTCGCTCGTCGACGCCAGCGATCTCTTTTTAGGGCGACTCA
AAGGCGTAGCCTCGCCAGAGAAGAAGCGCAAGATCATCGGGCGCACCTTCATTCAGGTGTTCGAAAAGAACATTCACGAC
GAGAAGTTCCTCGTGCAGGGCACGCTCTACCCGGACGTGATCGAGAGCGTCAGCGTGAAAGGACCGTCCGAGACGATCAA
GTCGCACCACAACGTCGGCGGCCTGCCGAAGCGCATGAAGCTCAAGCTCATCGAGCCGCTGCGCGAGCTGTTCAAGGATG
AAGTCCGCGCCGTCGGACGCGAGCTTGGCATCGCCGAGGACATCCTGATGCGCCACCCCTTCCCCGGCCCCGGCCTCGCC
GTGCGCGTGCTCGGCTCGCTCACGCGGGAGCGCCTCGACGTGCTGCGCGACGCCGACCAGATTTTCATCGACGAGCTGAA
GTCGAGCGGCCTCTACTCGAAGGTGTGGCAGGCCTTCTCGGTGCTCCTGCCGGTGCAGTCGGTCGGCGTGATGGGCGACA
AACGCACCTACGAAAACGTGCTCGCCTTGCGAGCCGTGGAATCCACCGACGGCATGACCGCCGACTGGGCGCACCTCCCC
CACGACTTCCTCGCCAAAGTCTCGAACCGCATCATCAACGAAGTGAGAGGCATCAACCGTGTGGTATACGATATTTCCTC
GAAACCGCCAGCCACGATCGAGTGGGAGTGA

Protein sequence :
MATSLQSVIVLDFGSQYTQLIARRIREIGIYSEIFPYHTKAETIRAHQPKAIILSGGPNSVYDEKAFMPDPEVFSLGVPV
LGICYGLQAIAKHFGGNVESSSKQEFGRAKMLVNHDESESLLFRDIPDSDVWMSHGDKVTQLPEGFRVTASTANAEVCAI
ESFGSKAALKVYGLQFHPEVQHSLYGKQLLSNFLIDIAGITPDWSPKSFIQHQIEEIKRVAGDSTVVCGISGGVDSTVAA
VLVSKAIGDKLHCVFVDNGLLRKDEAVKVMEFLKPLGLNISLVDASDLFLGRLKGVASPEKKRKIIGRTFIQVFEKNIHD
EKFLVQGTLYPDVIESVSVKGPSETIKSHHNVGGLPKRMKLKLIEPLRELFKDEVRAVGRELGIAEDILMRHPFPGPGLA
VRVLGSLTRERLDVLRDADQIFIDELKSSGLYSKVWQAFSVLLPVQSVGVMGDKRTYENVLALRAVESTDGMTADWAHLP
HDFLAKVSNRIINEVRGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-133 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-133 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-133 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-127 51