Gene Information

Name : thiC (CT1442)
Accession : NP_662328.1
Strain : Chlorobium tepidum TLS
Genome accession: NC_002932
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 1352637 - 1354307 bp
Length : 1671 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAACCAAGAGAACGCATCCTGCCCCAAAAAACACTTTTTCGGCCCTGCATCATCCCGAATCACCGTCAAAGGCACCAT
CTACCCGATCGAGGTCGGCATGAGGCGCGTCGCCCTCACCCGCAGCTACGAGTGCAAGGGCGAGCGTTTCGACGCGATGC
CGCTCTATGACACCAGCGGTCCGTTCGGCGACGCAGAGCGCGAGCACGACGTGCGTAAAGGACTGGAACCGGTGCGCGAC
CGCTGGGGCTTCGACCGCGGCACGGTGGAGTCAGTGGGTGGCGAACTTTCGATGACAGGACGCAAGCCGCGCGTGGCGAA
GGCGGGCGAGGCGGTGACGCAGATGCACTTCGCCCGCAAGGGGATCGTGACGCCGGAGATGGAGTACGTCGCCATCCGCG
AGAACCAGGCGCTCGAAGCGTGGATCGAAAAATGCGGCGGCAAACCGGTGACGCCGGAGATGGTGCGAAGCGAGGTGGCG
CGGGGACGGGCGATCATCCCAGCCAACATCAACCACCCGGAGATCGAACCGATGATCATCGGGCGCAACTTCCGGGTCAA
GATCAACGCCAACATCGGCAACTCGGCGCTTGGTTCGTCGATTGACGAAGAGGTGGAAAAAGCGGTCTGGTCGTGCCGCT
GGGGGGCGGACACGGTGATGGATCTCAGCACCGGCAAGAACATCCACCAGACCCGCGAGTGGATTCTGCGCAACTCGCCC
GTGCCGATCGGCACGGTGCCTCTCTACCAGGCACTCGAAAAGGTTGGCGGCAAGGCCGAGGAGCTGAGCTGGGAGGTCTA
CCGCGACACGCTCGTCGAGCAGGCCGAGCAAGGGGTAGACTACTTCACCATCCACTCGGGCATCCTCGCCGCCACCTTGC
CTGACGCCGAAGCGCGGCAGACCGGCATCGTTTCACGCGGCGGCTCGATCATGGCTCGCTGGTGCCGCGCCCACAAGCAG
GAGAACTTCCTCTTCACCCGCTTTGACGACATCTGCGACATCCTGCGCAGCTACGACGTCGCCATCTCGCTCGGCGACGC
GCTCCGTCCTGGATCGATTGGTGACGCCAACGACGCCGCGCAGTTCGGCGAGCTGAAGACACTCGGTGAGCTGACCCTCC
GCGCCTGGAAGCGCGACGTGCAGGTGATGATCGAAGGCCCCGGCCACGTGCCGCTACACATGATCCGCGAGAACATGGAG
ATGCAGCTCAAGCACTGCCACGAAGCGCCGTTCTATACCCTCGGCCCGCTCGTGACTGACGTGGCCGCCGGATACGACCA
TGTCAATTCGGCCATCGGCGGCACGCTCATCGCCAGCCTCGGCTGCTCGATGCTCTGCTACGTCACGCCGAAAGAGCACC
TCGGCCTACCCAACCGCGATGACGTGCGCGAAGGCGTCATCGTTCACCGCGTCGCCGCCCATGCCGCCGACATCGCCAAG
GGAAGCGCCACCGCCTGGCTGCGCGACGAGCTGATGAGCAAGGCCCGCTACGCCTTCGCGTGGGAAGACCAGTTCAGCCT
CGCCCTCGACCCGCTCAAGACGCGGCAAATCCACGCCCAGAACATCGCCGCCACCGGCGACACCTCCGCCACTGCAAAGT
ATTGCACCATGTGCGGCCCCGACTTCTGCTCGATGAAAAGGTCACAGGAAACGACTGCCGCGGGGTTGTAA

Protein sequence :
MNQENASCPKKHFFGPASSRITVKGTIYPIEVGMRRVALTRSYECKGERFDAMPLYDTSGPFGDAEREHDVRKGLEPVRD
RWGFDRGTVESVGGELSMTGRKPRVAKAGEAVTQMHFARKGIVTPEMEYVAIRENQALEAWIEKCGGKPVTPEMVRSEVA
RGRAIIPANINHPEIEPMIIGRNFRVKINANIGNSALGSSIDEEVEKAVWSCRWGADTVMDLSTGKNIHQTREWILRNSP
VPIGTVPLYQALEKVGGKAEELSWEVYRDTLVEQAEQGVDYFTIHSGILAATLPDAEARQTGIVSRGGSIMARWCRAHKQ
ENFLFTRFDDICDILRSYDVAISLGDALRPGSIGDANDAAQFGELKTLGELTLRAWKRDVQVMIEGPGHVPLHMIRENME
MQLKHCHEAPFYTLGPLVTDVAAGYDHVNSAIGGTLIASLGCSMLCYVTPKEHLGLPNRDDVREGVIVHRVAAHAADIAK
GSATAWLRDELMSKARYAFAWEDQFSLALDPLKTRQIHAQNIAATGDTSATAKYCTMCGPDFCSMKRSQETTAAGL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 3e-163 60
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 3e-163 60
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 1e-155 57