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Name : folA (BP3155) Accession : NP_881720.1 Strain : Bordetella pertussis Tohama I Genome accession: NC_002929 Putative virulence/resistance : Resistance Product : dihydrofolate reductase Function : - COG functional category : H : Coenzyme transport and metabolism COG ID : COG0262 EC number : 1.5.1.3 Position : 3365695 - 3366198 bp Length : 504 bp Strand : + Note : Similar to Escherichia coli dihydrofolate reductase FolA or TmrA or B0048 SW:DYR_ECOLI (P00379) (159 aa) fasta scores: E(): 1.9e-23, 46.54% id in 159 aa, and to Salmonella typhimurium dihydrofolate reductase type III DhfrIII SW:DYR3_SALTY (P12833) (162 aa DNA sequence : TTGCCCATGTCCGCCACTCCCCTGCTCAGCCTGGTCGTCGCCTATTCGACCAACCGCGTCATCGGACGCGACAACGCCCT GCCCTGGAAGCTGCCCGGCGACCTGGCGCACTTCAAGCGCACGACCCTCGGCCATCCCATCATCATGGGCCGCAACACCT GGGAATCGCTGGGCCGCCCGCTGCCGGGGCGCACCAATATCGTGATCACCCGCAACCCGGCCTATGACGCCGCCGGCGCC GTGGTGGTGGGCTCGCTTGCCGCCGCCATCCAGGCCTGCGGCGACGCCGCCGTGGCCTGCGTCATCGGCGGCGCGCAGAT CTACGCCCAGGCCCTGCCGCTGGCGCAGCGCGTGGTGGCCACCGAGGTGCATGCCGAGATCGAGGGCGACGCTTTCTTCC CGCCGCTGCCGGCCGGGCAGTGGCGCGAAACGCAGCGCGCGGCGCAACCGGCCGAGAACGGCCTGCGCTACGACTTCGTG GAATACGAGCGCGTGGCGGGCTGA Protein sequence : MPMSATPLLSLVVAYSTNRVIGRDNALPWKLPGDLAHFKRTTLGHPIIMGRNTWESLGRPLPGRTNIVITRNPAYDAAGA VVVGSLAAAIQACGDAAVACVIGGAQIYAQALPLAQRVVATEVHAEIEGDAFFPPLPAGQWRETQRAAQPAENGLRYDFV EYERVAG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| dfrA12 | ACF06156.1 | dihydrofolate reductase | Not tested | Tn5036-like | Protein | 1e-21 | 42 |
