Gene Information

Name : wbpO (BP3150)
Accession : NP_881715.1
Strain : Bordetella pertussis Tohama I
Genome accession: NC_002929
Putative virulence/resistance : Virulence
Product : polysaccharide biosynthesis protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 3360205 - 3361479 bp
Length : 1275 bp
Strand : -
Note : Similar to Salmonella typhi Vi polysaccharide biosynthesis protein VipA or TviB or Sty4661 SW:VIPA_SALTI (Q04972) (425 aa) fasta scores: E(): 1.1e-118, 68.72% id in 422 aa, and to Pseudomonas aeruginosa WbpO TR:Q9RHD7 (EMBL:AF035937) (422 aa) fasta scores

DNA sequence :
TTGCGCATTGATGATGTGAAACTGGCCGTTGTCGGCCTCGGATACGTGGGGCTGCCGCTGGCCGTGGAGTTCGGCAAGAA
ACGCCCGGTGATCGGCTTCGATATCAACGAGCGCCGCATCGCCGCGCTCAAGGCCGGCCACGATCACACCCTGGAAGTCG
AGGACGACGAACTGGCCCGGGCCGCGCAGCTCAGCTACACCGCCGAGCGCGAGGAACTGGGCAAGGCCAATGTGTTCATC
GTCACCGTGCCCACGCCGATCGACGAGTACAAGCAGCCCGACCTCACGCCGCTGGTCAAGGCCAGCGAGACCATCGGCGC
GGTGCTCAAGCGCGGCGACATCGTGATCTACGAATCGACCGTGTACCCGGGCGCCACCGAGGAAGACTGCGTGCCGGTGC
TCGAGCGCGTGTCGGGCCTGAAGTTCAACCAGGACTTCTACGCCGGCTACAGCCCCGAGCGCATCAACCCGGGCGACAAG
GCGCACCGCGTCAACACCATCAAGAAGGTGACCTCGGGCTCGACGCCGGAAGTCGCCGAGCTGGTCGACCAGCTGTACAA
CGAGATCATCACGGCCGGCACCCACAAGGCCTCGAGCATCCGCGTGGCCGAGGCCGCCAAGGTGATCGAGAACACGCAGC
GCGACGTCAACATCGCGCTGATCAACGAGCTGGCGCTGATCTTCAACAAGATGGGCATCGACACCGAGGCCGTGCTGCAG
GCCGCCGGCACCAAGTGGAACTTCCTGCCGTTCCGTCCGGGCCTGGTGGGCGGGCACTGCATCGGCGTGGATCCGTACTA
CCTGACGCACAAGGCGCAGGCCATCGGCTACCACCCTGAGATCATCCTGGCGGGCCGCCGCCTGAACGACTCGATGGGCG
GCTACGTGGTCTCGCAGCTGGTCAAGGCCATGGCCAAGCGCCGCATCCACGTCGAGGGCGCGCGCGTGCTGCTGATGGGC
CTGACGTTCAAGGAAAACTGCCCCGACCTGCGCAACACGCGCGTGGTGGACATCGTGCGCGAGCTGGGCGAGTACCACGT
CGACGTGGACGTGTACGACCCGTGGGTGGACCCGGCCGAGGCCGAGCACGAGTACGGCATCACGCCGGTCGCCAAGCCGG
CCGCCGGGGCGTACGACGCGATCATCCTGGCGGTGTCGCACCACCAGTTCGTCGAGATGGGCGCCGAGGCGATCCGCAAG
TTCGGCAAGGCCGAGCACATCCTGTACGACCTGAAGTACGTGCTGGCCCCCGAGCAGGCCGACCTGAGGCTGTAA

Protein sequence :
MRIDDVKLAVVGLGYVGLPLAVEFGKKRPVIGFDINERRIAALKAGHDHTLEVEDDELARAAQLSYTAEREELGKANVFI
VTVPTPIDEYKQPDLTPLVKASETIGAVLKRGDIVIYESTVYPGATEEDCVPVLERVSGLKFNQDFYAGYSPERINPGDK
AHRVNTIKKVTSGSTPEVAELVDQLYNEIITAGTHKASSIRVAEAAKVIENTQRDVNIALINELALIFNKMGIDTEAVLQ
AAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAQAIGYHPEIILAGRRLNDSMGGYVVSQLVKAMAKRRIHVEGARVLLMG
LTFKENCPDLRNTRVVDIVRELGEYHVDVDVYDPWVDPAEAEHEYGITPVAKPAAGAYDAIILAVSHHQFVEMGAEAIRK
FGKAEHILYDLKYVLAPEQADLRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 9e-145 69
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 9e-145 69
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-112 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
wbpO NP_881715.1 polysaccharide biosynthesis protein VFG0431 Protein 4e-145 69