Gene Information

Name : BP2768 (BP2768)
Accession : NP_881372.1
Strain : Bordetella pertussis Tohama I
Genome accession: NC_002929
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2944283 - 2945047 bp
Length : 765 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
GTGAGCTTTACCGTCCTGATCCCGGCGCGCCTGGCGTCCACCCGCCTGCCCGACAAGCCGCTGGCCGACATCGCCGGCAA
GCCCATGGTGGTGCGCGTGGCCGAACGCGCCGCGCTGTCGGGCGCAGAGCGCGTCATGATCGCCACCGACGATGCGCGCG
TCCAGCAAGCGGCCGCCGCCCATGGCCATGCCGCCATCCTGACCCGTCCCGACCACCCCACCGGCACCGACCGCCTGTCC
GAGGCCGTCGACGCGCTGGGGCTGCCCGATGACGCCATCGTCGTCAACGTACAGGGCGACGAGCCGCTGATCGAACCGGC
CCTGATCGACGCGGTCGCCGCCCAGCTGGTGGCCGCCCCGCATGCCGATATCGCCACCTGTGCCTGTCCGCTGGCCGATG
CCGAGGCGCTGTTCAACCCCAATGTCGTGAAAGTGGTGTGCACGGCCGACCGGCGCGCCCTGTACTTCTCGCGCGCCCCC
ATCCCGTGGGCGCGCGACGCCCTGGCCGGCGGCGCACGGGTTCTTGCCCCCGGCCTGCCCGCCTGGCATCACATCGGCAT
CTATGCCTATCGCGTGGCCTTCCTACGCCGTTTCCCGGCCCTGTCGCAGGGACAGCTGGAACGCTACGAATCGCTGGAAC
AGCTGCGCGCGATGGAGCACGGCCACGTTATCGTGGTGCACCATACCGACAGCGCGCCCGCCGCCGGCGTGGACACGCCA
GCCGACCTGGAACGTGCCCGGGCCGCATACACGAATCGGTTATAA

Protein sequence : 
MSFTVLIPARLASTRLPDKPLADIAGKPMVVRVAERAALSGAERVMIATDDARVQQAAAAHGHAAILTRPDHPTGTDRLS
EAVDALGLPDDAIVVNVQGDEPLIEPALIDAVAAQLVAAPHADIATCACPLADAEALFNPNVVKVVCTADRRALYFSRAP
IPWARDALAGGARVLAPGLPAWHHIGIYAYRVAFLRRFPALSQGQLERYESLEQLRAMEHGHVIVVHHTDSAPAAGVDTP
ADLERARAAYTNRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 4e-27 45
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 6e-27 45
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 7e-27 45