Gene Information

Name : BP2722 (BP2722)
Accession : NP_881330.1
Strain : Bordetella pertussis Tohama I
Genome accession: NC_002929
Putative virulence/resistance : Resistance
Product : membrane transport ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 2888065 - 2890401 bp
Length : 2337 bp
Strand : -
Note : Similar to Pseudomonas putida Cadmium-Transporting ATPase CadA TR:AAK48831 (EMBL:AF333961) (737 aa) fasta scores: E(): 6.3e-147, 62% id in 737 aa and to Pseudomonas aeruginosa probable metal-transporting P-type ATPase pa3690 TR:Q9HXV0 (EMBL:AE004788) (740

DNA sequence :
ATGCCCTCCACGACCCGCGACCTTGCCCTCGATATGCCATCTGGCCAACGCACGGACGCCCACGGCCACGACCACGCAGG
CCACGACCACGCAGGCCATGACCATGCCGGGCACGACCATGCCCACGACCATGGCATCCCGGCCTGCTGCGGCCATGGGC
ACGGCCAGCCGGCCGCGCCCGCGGCCGCCCCGGCCTGGCAGCCCGGTCCGGGCCAGCAGGTCACGCGGGTGCGCATCGGG
CAGATGGACTGCCCCACCGAGGAAACGCTGATCCGCAAGAAGCTGGCCAGCCTGCCCGAGGTGCACGAGCTCGACTTCAA
CCTGATGCAGCGCGTACTGATCGTGCTGCATGCCGACGGCGCGCTCGATCGCATCGACGCGGCGATCCGCTCGCTGGGCA
TGACGCCCGAGCCCCTGGCCGGCGACGCCCCGGCGACCCCAGCCGGCGCGGCCGCGCCTTCGCGCGGCTGGCGCCTGCTG
GCCGCCGGCGGGGTGCTGGCGGCGCTGTCCGAGCTCGCCCACTTCACCGGCCAGCCGGTCTATGTCGCCGCCGCCCTGGC
GCTGGCGGCCATCCTGGCCTGCGGGCTGTCGACCTACCGCAAGGGCTGGATCGCGGTGCGCAACGGCAATCTCAACATCA
ATGCCCTGATGAGCATCGCCGTGACCGGCGCGATGCTCATCGGCCAATGGCCGGAAGCGGCCATGGTGATGTTCCTGTTC
AACGTGGCCGAGCTGATCGAGGCCCGCGCCCTGGACCGCGCCCGCCATGCGGTGCGCGGCCTGCTGGACCTGGCGCCGCA
GACCGCCACCGCGCGCCAGCCGGACGGCTCGTGGGCCGAGGTGCCGGCGGCGCGACTGCGCCCGGGCGACCTGGTGCGGG
TGCGCCCGGGCGAGCGCATCGCCGCCGACGGCACCATCAGCGAAGGCCAGTCCGCGATCGACCAGTCGCCCATCACCGGC
GAAAGCCTGCCGGTGGAAAAAGGCCCGGACGACGACGTCTACGCCGGCACCGTCAATGCCTCCGGGTCGTTCGACTACCG
CGTCACGGCGGCGGCCGGCAATACCACGCTGGACCGCATCATCCACGCGGTCGAACAGGCCCAGGGCGCGCGCGCCCCGA
CCCAGCGCTTCATCGACCGCTTCTCGCGCATCTACACGCCGGCCGTGGTCGGGCTGGCGGTGCTGGTCGCGCTGGCGCCG
CCGCTGCTGCTGGGCCACGCCTGGCTCGACTCCGTGTACCGCGCGCTGGCGCTGCTGATCATCGCCTGCCCCTGCGCGCT
GGTGATTTCCACCCCGGTCAGCGTGGTCAGCGGCCTGACCGCCGCCGCGCGGCGCGGCATCCTGATCAAGGGCGGCGTCT
ACCTGGAGGAAGGACGCAAGCTGCGCTGGCTGGCGCTGGACAAGACCGGCACGCTGACCCAGGGCAAGCCGGTGCAGACC
GACCTGGAACTGCTGCACGACGCCAGCGCGGGCGGGCGCCCGGCGCTGCGCGCCGCGGTCAGCCTGGCGGCGCGCTCGGA
CCACCCCGTGTCGCGCGCGCTGGCCCAGGCCGACCACGCCCTGGACGCGCCGCTGGACGAGGTGAACGGTTTCGCCGCCC
TGCCCGGCCGCGGCGTGCAGGGCGAGATCGGCGGCGAGCGCTTCCAGCTGGGCAACCGCCGCCTGATGCGCGAGCTGGGC
GTCAGCACGCCCGATATCGAGGCCCGCATCGACGCCTATGAAGCGGCCGGCAAGACCGCCATCGCCCTGGCCGACGGGCA
GCGCGTCCTGCTGCTGGCCGCGGTGGCCGACACGCTCAAGGCCAGCAGCGCCGCCGCCGTGGCCGACCTGCACCGGTTGG
GCGTGCGCACCCTCATGCTGACCGGCGACAACACCCGCGCCGCCCAGGCGGTGGCCGCCCAGGCCGGCATCGACGAGGCG
CGCGGCGACCTGCTGCCGCAGGACAAGCTGGACGCCGTCGAGGCCAAGCTGGATCCGGCCCTGCGCGTGGGCATGGTGGG
CGACGGCATCAACGACGCGCCGGCGCTGGCGCGCGCCGACATCGGCTTCGCCATGGGCGCGGCCGGCACCGGCACCGCCA
TCGAAACCGCCGACGTGGCGCTGATGGACGACGACCTGCGCAAGATCGGCACGTTCGTGCGCCTGTCGCGCGCCACCCAC
CGCATCCTGACCCAGAACATCGTCCTGGCGCTGGGCATCAAGGCGGTGTTCCTGGTGCTGGCGATGGCCGGCCAGGCCAC
GCTGTGGATGGCGGTGTTCGCCGACGTCGGCGCCAGCCTGCTGGTGGTCGCCAACGGCTTGCGGCTGCTGCGCGCGGGCA
GGCACCAGGCGTCCTGA

Protein sequence :
MPSTTRDLALDMPSGQRTDAHGHDHAGHDHAGHDHAGHDHAHDHGIPACCGHGHGQPAAPAAAPAWQPGPGQQVTRVRIG
QMDCPTEETLIRKKLASLPEVHELDFNLMQRVLIVLHADGALDRIDAAIRSLGMTPEPLAGDAPATPAGAAAPSRGWRLL
AAGGVLAALSELAHFTGQPVYVAAALALAAILACGLSTYRKGWIAVRNGNLNINALMSIAVTGAMLIGQWPEAAMVMFLF
NVAELIEARALDRARHAVRGLLDLAPQTATARQPDGSWAEVPAARLRPGDLVRVRPGERIAADGTISEGQSAIDQSPITG
ESLPVEKGPDDDVYAGTVNASGSFDYRVTAAAGNTTLDRIIHAVEQAQGARAPTQRFIDRFSRIYTPAVVGLAVLVALAP
PLLLGHAWLDSVYRALALLIIACPCALVISTPVSVVSGLTAAARRGILIKGGVYLEEGRKLRWLALDKTGTLTQGKPVQT
DLELLHDASAGGRPALRAAVSLAARSDHPVSRALAQADHALDAPLDEVNGFAALPGRGVQGEIGGERFQLGNRRLMRELG
VSTPDIEARIDAYEAAGKTAIALADGQRVLLLAAVADTLKASSAAAVADLHRLGVRTLMLTGDNTRAAQAVAAQAGIDEA
RGDLLPQDKLDAVEAKLDPALRVGMVGDGINDAPALARADIGFAMGAAGTGTAIETADVALMDDDLRKIGTFVRLSRATH
RILTQNIVLALGIKAVFLVLAMAGQATLWMAVFADVGASLLVVANGLRLLRAGRHQAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 7e-168 64
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 7e-94 45
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 6e-94 45
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-91 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BP2722 NP_881330.1 membrane transport ATPase BAC0298 Protein 4e-165 64
BP2722 NP_881330.1 membrane transport ATPase BAC0461 Protein 2e-71 43