Gene Information

Name : BP2547 (BP2547)
Accession : NP_881174.1
Strain : Bordetella pertussis Tohama I
Genome accession: NC_002929
Putative virulence/resistance : Virulence
Product : two-component response regulatory protein
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 2699535 - 2700224 bp
Length : 690 bp
Strand : +
Note : Similar to many regulatory proteins including: Salmonella typhimurium transcriptional regulatory protein TctD SW:TCTD_SALTY (P22104) (224 aa) fasta scores: E(): 1.8e-36, 50.000% id in 220 aa and Pseudomonas aeruginosa probable two-component response regul

DNA sequence : 
ATGCGTATCCTGATAGCTGAAGACGACAGCATCCTGGCCGACGGCCTGTCCCGCTCGCTGCGGCACAACGGCTATGCGGT
CGACGCCGTGCGCGACGGACTGGCCGCCGATTCGGCGCTGGCCGTCCAGCCCTTCGACCTGCTGATCCTCGATCTCGGCC
TGCCCCACCTGCCCGGGCTGGAGGTGCTGCGCAGGCTGCGCGCCCGCAACTCCGTGCTGCCGGTGCTGATCCTCACCGCC
GCCGACAGCATCGAACAGCGCGTCAAGGGCCTGGATCTCGGCGCCGACGACTACATGGCCAAGCCTTTCGCGCTGTCCGA
GCTCGAGGCCCGCGTGCGCGCCCTGACGCGGCGCGGCGCCGGCGGCGGCGCGACGATCGTGCGGCACGGCCGCCTGGTGT
TCGACCAGACGGGCCGCATCGCCACGGTCGACGACCAGACCCTGGACCTGTCCGCGCGCGAGGTCAGCCTGCTGGAGATC
CTGCTGGCGCGCAGCGGCCGCATGGTCAGCAAGACGCAACTGGTCGACCACCTTTGCGAATGGGGCGAGGAAGTCAGCAC
CAACGCCATCGAAGTCTATGTGCACCGCCTGCGCAAGAAACTCGAGCCCAGCGGCGTGAAAATCATCACCGTGCGCGGTC
TGGGCTATTGCCTCGAGCGGGACCAGGGTGCCTCGTATCTCGCCAGCTGA

Protein sequence : 
MRILIAEDDSILADGLSRSLRHNGYAVDAVRDGLAADSALAVQPFDLLILDLGLPHLPGLEVLRRLRARNSVLPVLILTA
ADSIEQRVKGLDLGADDYMAKPFALSELEARVRALTRRGAGGGATIVRHGRLVFDQTGRIATVDDQTLDLSAREVSLLEI
LLARSGRMVSKTQLVDHLCEWGEEVSTNAIEVYVHRLRKKLEPSGVKIITVRGLGYCLERDQGASYLAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
armR AAN62112.1 putative response-regulator ArmR Not tested PAGI-2(C) Protein 3e-26 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BP2547 NP_881174.1 two-component response regulatory protein BAC0083 Protein 9e-24 42
BP2547 NP_881174.1 two-component response regulatory protein BAC0487 Protein 4e-23 41
BP2547 NP_881174.1 two-component response regulatory protein BAC0638 Protein 2e-16 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BP2547 NP_881174.1 two-component response regulatory protein VFG0473 Protein 1e-27 45
BP2547 NP_881174.1 two-component response regulatory protein VFG1390 Protein 6e-24 43