Gene Information

Name : hemC (BP2537)
Accession : NP_881164.1
Strain : Bordetella pertussis Tohama I
Genome accession: NC_002929
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2688384 - 2689328 bp
Length : 945 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
GTGGCCGCTGTAGAACGCCTGACCATCGCCACGCGCGCCAGCCGGCTTGCCTTGTGGCAAGCCGAGCATGTGCGCGATCT
GCTGCGCGCGCGCTACCCGGCGTGCAGCGTCGAGTTGCTGACGCTGACCACGCGCGGCGACCAGATCCTGGACCGCACCC
TGTCCAAGGTGGGCGGCAAGGGCTTGTTCGTCAAGGAACTCGAAACCGCCTTGCTCGACGGCCGCGCCGATCTCGCGGTG
CATTCGCTCAAGGACGTGCCGGTGGACCTGCACGCGCCGTTCGAGCTGAGCTGCGTGCTCGAGCGCGCCGATCCGCGCGA
TGCGTTCGTCTCCAACGATTACGGCAGCCTGGCCGACCTGCCGCCCGGGGCGGCGGTCGGCACGTCCAGCCTGCGGCGCG
AGTCGCAGATCCGCGCCCGCTATCCGCACCTGGTCGTCAAGCCGCTGCGGGGCAATCTCGATACGCGCCTGGGCAAGCTG
GACAACGGCGATTACGCCGCCATCGTGCTGGCCGCGGCGGGCCTGGAGCGCCTGGGCCTGGCGGCCCGCATCCGCGCGCT
GCTGGAACCGGACGACAGCCTGCCCGCGGCCGGGCAGGGCGCGCTGGGCATCGAGATCCTGCAGGGCCGCGCCGATGTGC
GCGCCATGCTGGCGCCGCTGGGCGACGCCGCCACCCTGGCCTGCGTGACCGCCGAGCGCGCGGTCTCGCGCATGCTGGGC
GGATCGTGCCAGGTGCCGCTGGCGGCCTATGCCCGTATCGATGGCGATGAGCTCGCCTTGCGCGCGCTGGTCGCCGCGCC
CGACGGCCGCCGCATCGTGCGGGCCGAGCGCCGCGGTCCGCGCGACCAGGCCCAGGCCATCGGCGAGTCGGCCGCGCGCG
ACTTGCTGGCCGACGGCGCCGACGCAATACTGGCCGAATTGCTGCCAACCTCGCCCGCGCCTTGA

Protein sequence :
MAAVERLTIATRASRLALWQAEHVRDLLRARYPACSVELLTLTTRGDQILDRTLSKVGGKGLFVKELETALLDGRADLAV
HSLKDVPVDLHAPFELSCVLERADPRDAFVSNDYGSLADLPPGAAVGTSSLRRESQIRARYPHLVVKPLRGNLDTRLGKL
DNGDYAAIVLAAAGLERLGLAARIRALLEPDDSLPAAGQGALGIEILQGRADVRAMLAPLGDAATLACVTAERAVSRMLG
GSCQVPLAAYARIDGDELALRALVAAPDGRRIVRAERRGPRDQAQAIGESAARDLLADGADAILAELLPTSPAP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 9e-56 54
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 9e-56 54