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Name : bscN (BP2245) Accession : NP_880888.1 Strain : Bordetella pertussis Tohama I Genome accession: NC_002929 Putative virulence/resistance : Virulence Product : type III secretion system ATPase Function : - COG functional category : N : Cell motility COG ID : COG1157 EC number : - Position : 2370832 - 2372166 bp Length : 1335 bp Strand : - Note : Similar to many eg. Bordetella bronchiseptica BscN TR:O68539 (EMBL:AF049488) (444 aa) fasta scores: E(): 2.6e-162, 99.32% id in 444 aa, and to Pseudomonas aeruginosa ATP synthase in type III secretion system pa1697 TR:Q9I330 (EMBL:AE004596) (440 aa) fasta DNA sequence : ATGCGTCAGTACCACTACATCACGGAGATGATGCGGGTGGCCCTGCAGGATCTGTCCACGCTGCGGATAAAGGGCCGGGT GGTGCAAGTGGTGGGAACGATCATCAAGGCCGTCGTTCCGATGGTCAAGATCGGCGAAGTGTGCCTGCTGCGCAATCCCG GCGAGGACTTCGAGATGCACGGCGAAGTGGTGGGCTTTGTCCGCGACGCCGCCTTGCTCACGCCTATCGGCGACATGTAC GGGATTTCCTCGGCGACCGAGGTGATACCGACCGGACGCACGCATATGGTCCCCGTCGGTCCGGGCTTGCTGGGACGCGT GCTGGACGGGCTGGGACGTCCGCTGGACGCCGCCGAGTCAGGGCCGCTGCATGCCCACAAGTTCTATCCGGTCTTCGCCG ATGCGCCAGACCCGCTGACGCGTCGCATCATCCATGCTCCGCTGGAGCTGGGGGTGCGCGTACTGGACGGTTTGCTTACA TGCGGGGAAGGCCAGCGTCTGGGAATTTTCGCAGCCGCCGGCGGCGGCAAGTCGACCCTGCTGGGCATGCTGGTCAAGGG CGCCGCGGTCGACGTGACGGTGGTGGCGCTGATCGGCGAGCGTGGGCGGGAAGTTCGCGAGTTCCTTGAGCACGAACTCG GTCCGGAGGGCAGACGCAAGAGCGTGATCGTCTGCGCGACCAGCGACAAGTCCTCGATGGAGCGTGCCAAGGCGGCGTAC GTCGCAACCGCCATCGCCGAATACTTCCGCGATCAAGGGCAGCGTGTACTTTTTCTGATGGACTCGGTCACCCGCTTTGC GCGAGCCCAGCGTGAAATCGGCTTGGCGGCAGGCGAGCCGCCGACGCGGCGCGGCTATCCACCGTCGGTGTTCGCCACCT TGCCCAAACTGATGGAGCGCGCCGGCATGAACCAGACGGGTTCGATCACGGCGCTGTATACGGTGCTGGTCGAGGGGGAC GACATGAACGAACCGGTGGCCGACGAGACGCGTTCGATACTGGACGGCCACATCGTGCTCTCGCGCAAGCTGGGAGCGGC GAATCACTATCCTGCCGTCGACGTGCTGGCCTCGGCCAGCCGGGTCATGAATGCCGTGGTGTCGCCGCGTCACAAGTACC TGGCCGGACGTATGCGCGAACTGATGGCCAAGTACCAGGATGTCGAGCTGTTGGTGAAAATCGGCGAGTACAAGCAGGGC GCCGATGCGTCGACCGATGAGGCGATACAGAAGATCGGACAGATCAATGCGTTTCTCAGACAACTAACCGACGAACGCGA AGCATTCGAGGATACCGTACTGCGCATGGCTGAAATCATCGGACCCGAATCCTAA Protein sequence : MRQYHYITEMMRVALQDLSTLRIKGRVVQVVGTIIKAVVPMVKIGEVCLLRNPGEDFEMHGEVVGFVRDAALLTPIGDMY GISSATEVIPTGRTHMVPVGPGLLGRVLDGLGRPLDAAESGPLHAHKFYPVFADAPDPLTRRIIHAPLELGVRVLDGLLT CGEGQRLGIFAAAGGGKSTLLGMLVKGAAVDVTVVALIGERGREVREFLEHELGPEGRRKSVIVCATSDKSSMERAKAAY VATAIAEYFRDQGQRVLFLMDSVTRFARAQREIGLAAGEPPTRRGYPPSVFATLPKLMERAGMNQTGSITALYTVLVEGD DMNEPVADETRSILDGHIVLSRKLGAANHYPAVDVLASASRVMNAVVSPRHKYLAGRMRELMAKYQDVELLVKIGEYKQG ADASTDEAIQKIGQINAFLRQLTDEREAFEDTVLRMAEIIGPES |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| lscN | AAO18044.1 | LscN | Virulence | TTSS locus | Protein | 2e-127 | 64 |
| hrpB6 | AAB08461.1 | HrpB6 | Virulence | Hrp PAI | Protein | 2e-108 | 57 |
| hrcN | YP_362163.1 | type III secretion system ATPase | Virulence | Hrp PAI | Protein | 2e-108 | 57 |
| hrcN | YP_198730.1 | type III secretion system ATPase | Virulence | Hrp PAI | Protein | 3e-109 | 56 |
| hrpB6 | AAF61281.1 | HrpB6 | Virulence | Hrp PAI | Protein | 2e-109 | 56 |
| hrpB6 | BAB07852.1 | HrpB6 | Virulence | Hrp PAI | Protein | 2e-109 | 56 |
| hrcN | NP_640767.1 | type III secretion system ATPase | Virulence | Hrp PAI | Protein | 3e-108 | 56 |
| hrcN | AAP34339.1 | HrcN | Virulence | Hrp PAI | Protein | 4e-109 | 56 |
| XC_3006 | YP_244074.1 | type III secretion system ATPase | Virulence | Hrp PAI | Protein | 2e-107 | 55 |
| hrcN | NP_636610.1 | type III secretion system ATPase | Virulence | Hrp PAI | Protein | 2e-107 | 55 |
| ssaN | NP_460380.1 | type III secretion system ATPase | Virulence | SPI-2 | Protein | 7e-86 | 53 |
| ssaN | CAA70537.1 | secretion system apparatus | Virulence | SPI-2 | Protein | 5e-86 | 53 |
| ssaN | NP_456113.1 | putative type III secretion ATP synthase | Virulence | SPI-2 | Protein | 3e-86 | 53 |
| ssaN | NP_805086.1 | type III secretion system ATPase | Virulence | SPI-2 | Protein | 3e-86 | 53 |
| ssaN | YP_216423.1 | type III secretion system ATPase | Virulence | SPI-2 | Protein | 9e-86 | 53 |
| hrcN | AAB06001.1 | HrcN | Virulence | Hrp PAI | Protein | 1e-87 | 53 |
| hrcN | AAR25633.1 | type III secretion cytoplasmic ATPase HrcN | Not tested | Not named | Protein | 2e-77 | 52 |
| YPO0267 | YP_002345348.1 | type III secretion system ATPase | Virulence | Not named | Protein | 4e-92 | 52 |
| hrcN | AAT96195.1 | HrcN | Virulence | T-PAI | Protein | 4e-83 | 52 |
| hrcN | AAT96141.1 | HrcN | Virulence | T-PAI | Protein | 5e-83 | 52 |
| hrcN | AAG33879.1 | HrcN | Virulence | Hrp PAI | Protein | 1e-79 | 51 |
| hrcN | NP_791227.1 | type III secretion cytoplasmic ATPase HrcN | Virulence | Hrp PAI | Protein | 1e-82 | 51 |
| hrcN | ABA47275.1 | HrcN | Virulence | S-PAI | Protein | 5e-88 | 50 |
| hrcN | AAT96339.1 | HrcN | Virulence | S-PAI | Protein | 2e-83 | 50 |
| escN | AFO66300.1 | putative LEE-encoded type III secretion system ATPase | Virulence | SESS LEE | Protein | 5e-88 | 49 |
| escN | AFO66415.1 | putative LEE-encoded type III secretion system ATPase | Virulence | SESS LEE | Protein | 5e-88 | 49 |
| hrcN | AAT96258.1 | HrcN | Virulence | S-PAI | Protein | 7e-83 | 49 |
| hrcN | AAT96299.1 | HrcN | Virulence | S-PAI | Protein | 6e-83 | 49 |
| escN | CAC81862.1 | EscN protein | Virulence | LEE II | Protein | 3e-84 | 47 |
| escN | YP_003232153.1 | T3SS structure protein EscN | Virulence | LEE | Protein | 3e-84 | 47 |
| escN | AAK26715.1 | EscN | Virulence | LEE | Protein | 2e-84 | 47 |
| escN | YP_003236088.1 | translocator EscN | Virulence | LEE | Protein | 2e-84 | 47 |
| escN | AAL57542.1 | EscN | Virulence | LEE | Protein | 2e-84 | 47 |
| escN | NP_290268.1 | hypothetical protein | Virulence | LEE | Protein | 2e-84 | 47 |
| escN | AAC38383.1 | EscN | Virulence | LEE | Protein | 2e-84 | 47 |
| ECs4568 | NP_312595.1 | EscN | Virulence | LEE | Protein | 2e-84 | 47 |
| escN | AAC31513.1 | L0034 | Virulence | LEE | Protein | 1e-84 | 47 |
| unnamed | ACU09458.1 | type III secretion apparatus H+-transporting two-sector ATPase | Virulence | LEE | Protein | 1e-84 | 47 |
| invC | AAS66861.1 | InvC | Not tested | SSR-2 | Protein | 7e-80 | 46 |
| ysaN | AAS66842.1 | YsaN | Not tested | SSR-1 | Protein | 7e-73 | 44 |
| spaI | NP_806497.1 | ATP synthase SpaL | Virulence | SPI-1 | Protein | 6e-76 | 43 |
| invC | NP_461815.1 | ATP synthase SpaL | Virulence | SPI-1 | Protein | 6e-76 | 43 |
| invC | YP_217813.1 | ATP synthase SpaL | Virulence | SPI-1 | Protein | 6e-76 | 43 |
| spaI | NP_457288.1 | secretory apparatus ATP synthase (associated with virulence) | Virulence | SPI-1 | Protein | 6e-76 | 43 |
| ECs3730 | NP_311757.1 | ATP synthase SpaL | Not tested | LIM | Protein | 2e-72 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| bscN | NP_880888.1 | type III secretion system ATPase | VFG0048 | Protein | 0.0 | 100 |
| bscN | NP_880888.1 | type III secretion system ATPase | VFG0192 | Protein | 2e-129 | 68 |
| bscN | NP_880888.1 | type III secretion system ATPase | VFG0390 | Protein | 3e-130 | 65 |
| bscN | NP_880888.1 | type III secretion system ATPase | VFG2144 | Protein | 1e-104 | 55 |
| bscN | NP_880888.1 | type III secretion system ATPase | VFG0515 | Protein | 3e-86 | 53 |
| bscN | NP_880888.1 | type III secretion system ATPase | VFG0812 | Protein | 6e-85 | 47 |
| bscN | NP_880888.1 | type III secretion system ATPase | VFG0730 | Protein | 1e-84 | 47 |
| bscN | NP_880888.1 | type III secretion system ATPase | VFG2459 | Protein | 8e-83 | 45 |
| bscN | NP_880888.1 | type III secretion system ATPase | VFG2331 | Protein | 2e-71 | 45 |
| bscN | NP_880888.1 | type III secretion system ATPase | VFG1254 | Protein | 3e-80 | 45 |
| bscN | NP_880888.1 | type III secretion system ATPase | VFG0555 | Protein | 3e-76 | 43 |
| bscN | NP_880888.1 | type III secretion system ATPase | VFG1008 | Protein | 7e-75 | 43 |
| bscN | NP_880888.1 | type III secretion system ATPase | VFG1778 | Protein | 1e-74 | 43 |
| bscN | NP_880888.1 | type III secretion system ATPase | VFG2499 | Protein | 6e-71 | 41 |
