Gene Information

Name : acoD (BP2157)
Accession : NP_880809.1
Strain : Bordetella pertussis Tohama I
Genome accession: NC_002929
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 2277421 - 2278941 bp
Length : 1521 bp
Strand : -
Note : Similar to Alcaligenes eutrophus acetaldehyde dehydrogenase II AcoD SW:DHA2_ALCEU (P46368) (506 aa) fasta scores: E(): 1.1e-155, 74.65% id in 509 aa

DNA sequence : 
ATGGATCTATCCGACCTGAAAAAATTGGGCCTGGATGTGGCCTACCCGTTCAAGGAACAGTACGAGAACTACATCGGCGG
CCAATGGGTGGCTCCGGCAGGCGGGGAGTACTTCGACAATCTGTCGCCCATTACCGGCCAGCCGTTTTGCCGCGTGCCGC
GCTCGGGCGCGGCCGACGTCGAACTGGCGCTGGACGCGGCGCATCGCGCGTGCGCCGCGTGGGCGCGCACCTCGCCCGCC
GAGCGGGCCAACATCCTGCTGCGCATCGCCGACCGCATCGAGGGACAGTTGCCCATGCTGGCGGTGGCCGAGTCGATCGA
CAACGGCAAGCCGCTGCGCGAGACCACCGCGGCCGACCTGCCGCTGGCGATCGACCATTTCCGCTATTTCGCGGGCTGCA
TCCGGGCGCAGGAGGGCGCCATCTCGGAGATCGACGCCAACACCGTGGCCTACCACTTCCACGAACCCATCGGCGTGGTG
GGGCAGATCATTCCCTGGAACTTCCCGCTGCTGATGGTGGCTTGGAAGCTGGCGCCGGCGCTGGCGGCGGGCTGCGTGGT
GGTGCTCAAGCCGGCCGAACAGACGCCGGCCTCGATCCTGGTGCTGGCCGAACTGATCGGCGACCTGCTGCCGCCGGGCG
TGCTCAACGTGGTCAACGGCTATGGCAAGGAGGCCGGCCAGGCGCTGGCCACCAGCAAGCGCATCGCCAAAATCGCCTTC
ACCGGGTCGACGCCGGTGGGCAAGCACATCCTGCACGCGGCGGCCGACAACCTGATCCCCGCCACGGTGGAGCTGGGCGG
CAAGAGCCCCAACATCTTCTTCGACGACGTGATGGACCACGACGACGAGTTCCTGGACAAGGCGCTCGAGGGCCTGGCCA
TGTTCGCGCTCAACCAGGGCGAGGTCTGCACCTGCCCGTCGCGCATCCTGATCCAGGAGTCGATCTACGAGCGCTTCATC
GAGAAGGCCATCGCGCGGGTGCAGTCCATCAAGACCGGCCATCCGCTCGATGCCGGCACCATGGTGGGCGCACAGGTCTC
GCAGGTGCAGATGGACAAGATCCTGTCCTATATCGATATCGGCCGCCAGGAGGGCGCGCAATGCCTGACCGGCGGCGCGC
GTAACGACATGCTGCCGGGCGGGCTGGACCAGGGTTTCTATGTCCAGCCGACCATGCTGCTGGGCAAGAACAGCATGCGC
ATCTTCCAGGAGGAAATCTTCGGGCCGGTCGCGGCGGTGGCCACCTTCAAGGACGAGGAAGAGGCCATCGCCATGGCCAA
CGACACGTTCTACGGCCTGGGCGCGGGCGTCTGGAGCCGCGACGGCGCGCGGGCCTACCGCGTGGGCCGCGGCATCGAGG
CCGGCCGGGTGTGGACCAATTGCTATCACCTGTATCCGGCGCATGCCGCCTTCGGCGGCTACAAGCAGTCCGGCATCGGG
CGCGAGGCGGCGCTGTCGAATTACCAGCAGACCAAGTGCCTGCTGGTGAGCTACAGCGCCAAGGCCCTGGGCTTCTTCTA
A

Protein sequence : 
MDLSDLKKLGLDVAYPFKEQYENYIGGQWVAPAGGEYFDNLSPITGQPFCRVPRSGAADVELALDAAHRACAAWARTSPA
ERANILLRIADRIEGQLPMLAVAESIDNGKPLRETTAADLPLAIDHFRYFAGCIRAQEGAISEIDANTVAYHFHEPIGVV
GQIIPWNFPLLMVAWKLAPALAAGCVVVLKPAEQTPASILVLAELIGDLLPPGVLNVVNGYGKEAGQALATSKRIAKIAF
TGSTPVGKHILHAAADNLIPATVELGGKSPNIFFDDVMDHDDEFLDKALEGLAMFALNQGEVCTCPSRILIQESIYERFI
EKAIARVQSIKTGHPLDAGTMVGAQVSQVQMDKILSYIDIGRQEGAQCLTGGARNDMLPGGLDQGFYVQPTMLLGKNSMR
IFQEEIFGPVAAVATFKDEEEAIAMANDTFYGLGAGVWSRDGARAYRVGRGIEAGRVWTNCYHLYPAHAAFGGYKQSGIG
REAALSNYQQTKCLLVSYSAKALGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-148 66
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-155 66
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-155 66
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-155 66
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-154 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
acoD NP_880809.1 aldehyde dehydrogenase VFG0082 Protein 1e-148 66