Gene Information

Name : BP0158 (BP0158)
Accession : NP_879051.1
Strain : Bordetella pertussis Tohama I
Genome accession: NC_002929
Putative virulence/resistance : Virulence
Product : two-component response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 157032 - 157709 bp
Length : 678 bp
Strand : -
Note : Similar to Escherichia coli transcriptional regulatory protein PcoR SW:PCOR_ECOLI (Q47456) (226 aa) fasta scores: E(): 4.7e-46, 53.846% id in 221 aa, and to Pseudomonas aeruginosa probable two-component response regulator Pa1437 TR:Q9I3R0 (EMBL:AE004573)

DNA sequence : 
ATGTGCATCCTCGTTATCGAAGACGAGCCCAAGCTGGCCGACTATCTGCACAAGGGCCTGTCCGAGCAAAGCCATATCGT
CGACGTCGCGCGCGACGGCGTCAACGGCCGCCACCTGGCGCTCGAGGGCGACTACGAACTGGTCATCCTCGACGTGATGC
TGCCCGACATCGACGGCTTCGCCGTCCTGGCGGCGCTGCGCGCGGCCGCGCGCAACACGCCGGTGCTGATGCTGACGGCG
CGCGACCGGGTCGAGGACCGCGTGCGCGGGCTGGAAGGCGGCGCCGACGACTACCTGGTCAAGCCGTTCGCGTTCTCCGA
GCTCCTGGCGCGCGTGCATGCGCTGCAGCGGCGCGGGCGCAGCCAGGAATCCACCCTGCTGCGCCTGGCCGACCTCGAGC
TGGACCTGGCCAGCCGCAAGGCGCAGCGCGGCGGACGCCGCCTGGACCTGACGGCCAAGGAGTTTTCGCTGCTGGCGCTG
CTGCTGCGCCGCCAGGGCCAGATCCTGTCGCGCACCACGCTGGCCGAGCAGGTCTGGGACATGAACTTCGACAGCGACAC
CAACGTCATCGACGTCGCCATCCGCCGGCTGCGCGGCAAGCTGGACGACCCCTACGACGCCAAGCTGCTGCATACCGTGC
GCGGCATGGGCTACGTGCTGGAATCGCGCCCGTCATGA

Protein sequence : 
MCILVIEDEPKLADYLHKGLSEQSHIVDVARDGVNGRHLALEGDYELVILDVMLPDIDGFAVLAALRAAARNTPVLMLTA
RDRVEDRVRGLEGGADDYLVKPFAFSELLARVHALQRRGRSQESTLLRLADLELDLASRKAQRGGRRLDLTAKEFSLLAL
LLRRQGQILSRTTLAEQVWDMNFDSDTNVIDVAIRRLRGKLDDPYDAKLLHTVRGMGYVLESRPS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 2e-46 55
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 6e-46 53

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BP0158 NP_879051.1 two-component response regulator BAC0197 Protein 1e-53 64
BP0158 NP_879051.1 two-component response regulator BAC0083 Protein 1e-53 61
BP0158 NP_879051.1 two-component response regulator BAC0125 Protein 2e-54 61
BP0158 NP_879051.1 two-component response regulator BAC0638 Protein 1e-46 59
BP0158 NP_879051.1 two-component response regulator BAC0111 Protein 4e-55 57
BP0158 NP_879051.1 two-component response regulator BAC0308 Protein 9e-51 54
BP0158 NP_879051.1 two-component response regulator BAC0347 Protein 2e-47 50
BP0158 NP_879051.1 two-component response regulator AE000516.2.gene3505. Protein 3e-22 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BP0158 NP_879051.1 two-component response regulator VFG0596 Protein 6e-47 55
BP0158 NP_879051.1 two-component response regulator VFG1389 Protein 5e-29 44
BP0158 NP_879051.1 two-component response regulator VFG1390 Protein 5e-34 41