Gene Information

Name : wcbA (BP1631)
Accession : NP_880359.1
Strain : Bordetella pertussis Tohama I
Genome accession: NC_002929
Putative virulence/resistance : Virulence
Product : capsular polysaccharide export protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3563
EC number : -
Position : 1715348 - 1717405 bp
Length : 2058 bp
Strand : +
Note : Similar to Escherichia coli capsule polysaccharide export protein KpsC SW:KSC5_ECOLI (P42217) (675 aa) fasta scores: E(): 1.9e-87, 42.81% id in 689 aa, and to Pasteurella multocida LipA TR:Q9L9L5 (EMBL:AF169324) (682 aa) fasta scores: E(): 1.5e-98, 42.28%

DNA sequence :
ATGATCGAGCTTCATTCGTCAGGCATCGCGCGTATTCCGTACCTGACGGAGCTGCTGGGCGCGCCGGTCACCCGCTACCG
GCGCTTCTGGCCGCCGGGCGGCGCGGCGCCGCGCGCGGTGGCGGGATGGGGCGCGCGCCCCAGCGCCGCGCCGGCGCGGC
GCCGCGCCCGTTCGCTGGGCGTGCCCTACATTGCGCTGGAAGACGGTTTCCTGCGCTCGTTCGGCACCGGGCGCCATTTT
CCGCCTCTGTCGCTGGTGGTCGATCGCCTGGGCATCTACTACGACGCGACGCGCGAATCCGAGCTGGAGTGCCTGCTGGC
GTCGTCGCGCACGCTGCTCGACGGCATCGAGGACGCCGTGCCCGAAGCCATGGAGCTGGTGCGCGAACGCCGCCTGTCGA
AGTACAACCAGGGCTGCTTCCTGGCCACCGGCGTGCCGGCCGACGGCCGGCGCCGGGTGCTGGTGGTGGACCAGACCGAA
GGCGACATGAGCGTGACCCTGGGTTGCGCCGAGGCGGCCACCTTCGAGGCCATGCTGGCGGCGGCGCGGGCGGAGAGCCC
TGGCGCGCTGATCTGCGTCAAGACGCATCCCGAGGTGGCGGCCGGCGACAAGTCGGGCTATCTGTCGCGGGTTACCGACG
ACGCCGATACGGTGGCGCTGCGCCACGACATGAATCCCCTGGCCTTGCTGGAACAGATGGACCGGGTCTATGTGGTCAGT
TCGCAGATGGGGTTCGAAGCCCTGATGCTGGACAAGCCCGTGACCTGCTTCGGCATGCCCTGGTATGCCGGCTGGGGCGT
GACCGACGATCGCCAGCGCTGCGAGCGGCGCGGCCGCGCGCGCAGCGTCGAGGAGCTGTTCGCCGGCGCGTATTTCCACT
ACACCCGCTACCTGGATCCGGTGCTGCATCGCCGCGGCACGATCTTCGACGTGATCGACTGGCTGACGCGCCAGCGCGAC
ATGGCGCAACGCCTGCCGTCGCGCGTGATCGGCGTGGGCATGCGCCGCTGGAAGGCGGCCGCGCTGGCGCCCATGCTGGC
GTTAAAGCCCGGCCAGGCGGTGTTCGCCGCCGACGCCGCCCGCGCGCGGGACCTGGGGCAGGCCGCGGGCGACGCCCTGG
TGCATTGGGGCGCCCGGGCGCCCGCCGGCGTGGCCGAGCTGGCCGAACAGAGCGGTTGCGCGGTGCTGGCCGTGGAGGAT
GGCTTCCTGCGGTCGGTCGGCCTGGGGTCGGACCTGATCCGGCCGCTGAGCCTGGCGCTGGACGGGCGGGGCATCTACTT
CGATCCCCGCCAGCCCAGCGATCTGGAGCATGAATTGAACCGGGGCGGGTTCAGCCCGGGAGAGCTGGCCAGTGCGGCGC
GCATCCGCGCGCTGGTGGTCGCCCACGGCATCACCAAGTACAACGTGGCGCAGCCCCAGCCGGCCGACTGGCCGGCGCGC
GGGCGCGAGATCGTGCTGGTGCCCGGCCAGGTCGAGGACGATGCGTCGGTGCGGCTGGGCTGCGACGAAGTCCGCACCAA
CCTGGACCTGCTGGCGGCCGCGCGCGCCGCGCATCCCGACGCCTACATCGTCTACAAGCCGCATCCGGACGTGGTCAGTC
GCAACCGCCGCGGCCGCGTGGCGCTGCGCGAGGCGCGCCGCCATGCCGATCATGTCGAGTCCGCGCTGTCGGTGGTCAGC
TGCATCCAGGCGTGCGACGTGGTGCACACCATGACCTCGCTGACGGGCTTCGACGCCTTGCTGCGCGGCAAGCGCGTGGT
GACGTACGGCAAGCCGTTCTATGCCGGCTGGGGCCTGACCGAGGACCGCGCCGCCGATTGGCCGCGCGACCGGCGCACCC
GCCGGCTGAGCCTGGACGAGCTGGTCGCCGGCACGCTGCTGCGCTATCCGCTGTACTGGGATTGGGAACTGCGCGGATAC
ACCACGTGCGAGGCGGTGCTGACGCATATTTTCGAGACGCGCGAACGCCTGCAGCGCGAAGGCCGCCTGCAAGGGCTGCG
CGCCGGCTATGCGCGCCGCCAGGTGCGCAAGCTGCAGACATTGTGGCTGGCCCGATGA

Protein sequence :
MIELHSSGIARIPYLTELLGAPVTRYRRFWPPGGAAPRAVAGWGARPSAAPARRRARSLGVPYIALEDGFLRSFGTGRHF
PPLSLVVDRLGIYYDATRESELECLLASSRTLLDGIEDAVPEAMELVRERRLSKYNQGCFLATGVPADGRRRVLVVDQTE
GDMSVTLGCAEAATFEAMLAAARAESPGALICVKTHPEVAAGDKSGYLSRVTDDADTVALRHDMNPLALLEQMDRVYVVS
SQMGFEALMLDKPVTCFGMPWYAGWGVTDDRQRCERRGRARSVEELFAGAYFHYTRYLDPVLHRRGTIFDVIDWLTRQRD
MAQRLPSRVIGVGMRRWKAAALAPMLALKPGQAVFAADAARARDLGQAAGDALVHWGARAPAGVAELAEQSGCAVLAVED
GFLRSVGLGSDLIRPLSLALDGRGIYFDPRQPSDLEHELNRGGFSPGELASAARIRALVVAHGITKYNVAQPQPADWPAR
GREIVLVPGQVEDDASVRLGCDEVRTNLDLLAAARAAHPDAYIVYKPHPDVVSRNRRGRVALREARRHADHVESALSVVS
CIQACDVVHTMTSLTGFDALLRGKRVVTYGKPFYAGWGLTEDRAADWPRDRRTRRLSLDELVAGTLLRYPLYWDWELRGY
TTCEAVLTHIFETRERLQREGRLQGLRAGYARRQVRKLQTLWLAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lipA NP_273145.1 capsule polysaccharide modification protein Not tested IHT-A Protein 3e-99 45
kpsC YP_854335.1 capsule polysaccharide export protein KpsC Not tested PAI I APEC-O1 Protein 2e-81 44
kpsC AAZ04470.1 capsule polysaccharide export protein Virulence PAI I APEC-O1 Protein 2e-81 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
wcbA NP_880359.1 capsular polysaccharide export protein VFG0692 Protein 9e-98 47
wcbA NP_880359.1 capsular polysaccharide export protein VFG0704 Protein 1e-89 46
wcbA NP_880359.1 capsular polysaccharide export protein VFG0259 Protein 1e-99 45