Gene Information

Name : wbpO (BP1629)
Accession : NP_880357.1
Strain : Bordetella pertussis Tohama I
Genome accession: NC_002929
Putative virulence/resistance : Virulence
Product : capsular polysaccharide biosynthesis protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 1713025 - 1714314 bp
Length : 1290 bp
Strand : +
Note : Similar to Pseudomonas aeruginosa WbpO TR:Q9RHD7 (EMBL:AF035937) (422 aa) fasta scores: E(): 3.1e-132, 80.23% id in 420 aa, and to Plesiomonas shigelloides orf1p WbgT TR:Q9S0Y5 (EMBL:AB025970) (437 aa) fasta scores: E(): 2.2e-120, 70.69% id in 430 aa. Alm

DNA sequence :
ATGCCGAAGAAGTTTTCCAATCCTGCAGATGTTCATCTCGCCGTCGTTGGCCTGGGGTATGTCGGGCTGCCGCTGGCCGT
GGAGTTCGGCAAGAAACGCCCGGTGATCGGCTTCGATATCAACGAGCGCCGCATCGCCGCGCTCAAGGCCGGCCACGATC
ACACCCTGGAAGTCGAGGACGACGAACTGGCCCGGGCCGCGCAGCTCAGCTACACCGCCGAGCGCGAGGAACTGGGCAAG
GCCAATGTGTTCATCGTCACCGTGCCCACGCCGATCGACGAGTACAAGCAGCCCGACCTCACGCCGCTGGTCAAGGCCAG
CGAGACCATCGGCGCGGTGCTCAAGCGCGGCGACATCGTGATCTACGAATCGACCGTGTACCCGGGCGCCACCGAGGAAG
ACTGCGTGCCGGTGCTCGAGCGCGTGTCGGGCCTGAAGTTCAACCAGGACTTCTACGCCGGCTACAGCCCCGAGCGCATC
AACCCGGGCGACAAGGCGCACCGCGTCAACACCATCAAGAAGGTGACCTCGGGCTCGACGCCGGAAGTCGCCGAGCTGGT
CGACCAGCTGTACAACGAGATCATCACGGCCGGCACCCACAAGGCCTCGAGCATCCGCGTGGCCGAGGCCGCCAAGGTGA
TCGAGAACACGCAGCGCGACGTCAACATCGCGCTGATCAACGAGCTGGCGCTGATCTTCAACAAGATGGGCATCGACACC
GAGGCCGTGCTGCAGGCCGCCGGCACCAAGTGGAACTTCCTGCCGTTCCGTCCGGGCCTGGTGGGCGGGCACTGCATCGG
CGTGGATCCGTACTACCTGACGCACAAGGCGCAGGCCATCGGCTACCACCCTGAGATCATCCTGGCGGGCCGCCGCCTGA
ACGACTCGATGGGCGGCTACGTGGTCTCGCAGCTGGTCAAGGCCATGGCCAAGCGCCGCATCCACGTCGAGGGCGCGCGC
GTGCTGCTGATGGGCCTGACGTTCAAGGAAAACTGCCCCGACCTGCGCAACACGCGCGTGGTGGACATCGTGCGCGAGCT
GGGCGAGTACCACGTCGACGTGGACGTGTACGACCCGTGGGTGGACCCGGCCGAGGCCGAGCACGAGTACGGCATCACGC
CGGTCGCCAAGCCGGCCGCCGGGGCGTACGACGCGATCATCCTGGCGGTGTCGCACCACCAGTTCGTCGAGATGGGCGCC
GAGGCGATCCGCAAGTTCGGCAAGGCCGAGCACATCCTGTACGACCTGAAGTACGTGCTGGCCCCCGAGCAGGCCGACCT
GAGGCTGTAA

Protein sequence :
MPKKFSNPADVHLAVVGLGYVGLPLAVEFGKKRPVIGFDINERRIAALKAGHDHTLEVEDDELARAAQLSYTAEREELGK
ANVFIVTVPTPIDEYKQPDLTPLVKASETIGAVLKRGDIVIYESTVYPGATEEDCVPVLERVSGLKFNQDFYAGYSPERI
NPGDKAHRVNTIKKVTSGSTPEVAELVDQLYNEIITAGTHKASSIRVAEAAKVIENTQRDVNIALINELALIFNKMGIDT
EAVLQAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAQAIGYHPEIILAGRRLNDSMGGYVVSQLVKAMAKRRIHVEGAR
VLLMGLTFKENCPDLRNTRVVDIVRELGEYHVDVDVYDPWVDPAEAEHEYGITPVAKPAAGAYDAIILAVSHHQFVEMGA
EAIRKFGKAEHILYDLKYVLAPEQADLRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 2e-143 69
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 2e-143 69
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 1e-112 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
wbpO NP_880357.1 capsular polysaccharide biosynthesis protein VFG0431 Protein 7e-144 69