Gene Information

Name : clpB (BP1198)
Accession : NP_879972.1
Strain : Bordetella pertussis Tohama I
Genome accession: NC_002929
Putative virulence/resistance : Virulence
Product : ATP-dependent protease, ATPase subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1258261 - 1260858 bp
Length : 2598 bp
Strand : +
Note : Similar to Escherichia coli clpB protein ClpB or HtpM or b2592 SW:CLPB_ECOLI (P03815) (857 aa) fasta scores: E(): 2.6e-183, 65.77% id in 862 aa, and to Neisseria meningitidis ClpB protein ClpB or Nma1683 TR:Q9JTP9 (EMBL:AL162756) (859 aa) fasta scores: E(

DNA sequence :
ATGCGATTCGACAAACTTACCACCAAGTTCCAGCAGGCCCTGGCGGACGCGCAAAGCCTGGCCGCCCGTAACGATCATCC
CTATATCGAGCCCGTCCATGTGCTGGCGGCCCTGTTGGGCGACCCCGACAGCGGCGCGGCCAGCCTGCTGGCGCGCGCCG
GCGTCGCCGTCAACCGCGTGCAGCCGGCCATCGACAGCGCCCTGAAAGGCCTGCCGCAGGTGCAGGGCGACGACAATGTC
CAGGTCGGGCGCGAGCTGCAAAGCGTGCTCGTGCGCACCGACAAGGAGGCCGCGCGGCGCGGCGACACCTACATCGCCAG
CGAGCTGTTCCTGCTGGCGCTGGCCGACGACAAGGGCGACGCCGGCCGCATCCTGCGCGAGGCGGGCCTGCAGAAGAAGG
CCCTGGAAGCGGCCATCGACGCCGTGCGCGGCGGCGAGAACGTCTCGGGCGCCGAAGGCGAGTCCAACCGCGAGGCGCTG
TCCAAGTACACGCTGGACCTCACCGAGCGCGCCCGCCAGGGCAAGCTGGATCCGGTCATCGGCCGCGACGACGAAATCCG
CCGCACCATACAGATCCTGCAGCGCCGCACCAAGAACAACCCCGTGCTGATCGGCGAACCCGGCGTCGGCAAGACCGCCA
TCGTCGAAGGGCTGGCGCAACGCATCGTCAACGACGAGGTGCCCGAGACGCTGCGCGGCAAGCGCGTGCTCTCGCTGGAC
CTGGCGGCGCTGCTTGCCGGCGCCAAGTTCCGTGGCGAGTTCGAGGAACGCCTGAAGGCCGTGCTCAAGGAGCTGGCCCA
GGACGACGGCCAGAACATCGTCTTCATCGACGAACTGCACACCATGGCCGGGGCGGGCAAGGCCGAAGGCGCCATGGACG
CCGGCAACATGCTCAAGCCGGCGCTGGCGCGCGGCGAGCTGCATTGCATCGGCGCCACCACGCTGGACGAATACCGCAAG
TACATCGAAAAGGATGCCGCGCTCGAGCGCCGCTTCCAGAAAGTGCTGGTCGGCGAGCCCGACGTGGAGTCCACCATCGC
CATCCTGCGCGGGCTGCAGGAGCGCTATGAGCTGCACCACGGCGTCGAGATCACCGATCCGGCCATCGTGGCGGCGGCCG
AGCTGTCGCACCGCTACATCACCGACCGGTTCCTGCCCGACAAGGCAATCGACCTGATCGACGAGGCCGGCGCACGCATC
CGCATGGAAATCGACTCCAAGCCCGAAGTGATGGACCGGCTGGACCGGCGCATCATCCAGCTCAAGATCGAACGCGAAGC
CGTCAAGAAGGAAACCGACGACGCCTCCATGCGCCGCCTGGCCGTGATCGAGGAAGAGCTGGAGAAGCTGCAGCGCGAAT
ACAACGACTACGAGGAAATCTGGAAAGCCGAGAAGGCCGCCGTGCAGGGCACGCAGGCCATCAAGGAAGAGATCGACCGC
GTGCGCGCCGAGATGGCCGAACTGCAGCGCAAGGGCCAGTTCGACAAGCTGGCCGAGCTGCAATACGGCAAGCTGCCCGA
GCTCGAGGCGCGCCTGAAGGCCGCCGACAGCGCCGAGCGTGAAGCCGGCGAATCCGACAGCGGCAAGCCGCGCCTGTTGC
GCACCCAGGTGGGCGCCGAGGAAATCGCCGAGGTCGTCTCGCGCGCCACCGGCATCCCGGTGGCCAAGATGATGCAGGGC
GAACGCGACAAGCTGCTGCGCATGGAAGATTTCCTGCACAAGCGCGTCGTGGGCCAGGACGAAGCCGTGCGGCTGGTTTC
CGATGCCATCCGGCGTTCGCGCGCGGGCCTGGCGGATCCGTCGCGCCCGTACGGTTCGTTCCTGTTCCTCGGGCCCACCG
GCGTGGGCAAGACCGAGCTGACCCGTGCCCTGGCGGATTTCCTGTTCGATTCCGAAGAGCACATGATCCGCATCGACATG
AGCGAATTCATGGAGAAGCATTCCGTGGCGCGGCTGATCGGCGCGCCGCCGGGATACGTGGGCTACGAAGAAGGGGGCTA
CCTGACCGAGGCGGTGCGCCGCAAGCCGTACAGCGTGATCCTGCTCGACGAGGTCGAAAAGGCGCACCCCGACGTGTTCA
ACGTGCTGCTGCAGGTGCTCGACGACGGCCGCCTGACCGATGGTCAGGGGCGCACGGTGGACTTCCGCAACACGGTCATC
GTCATGACGTCCAACCTTGGGTCGCAGCACATACAAAGCATGGCGGGCAAGCCGTACGAGGTCATCAAGGAAGTCGTGTG
GGACGAGCTCAAGCACACGTTCCGCCCCGAGTTCCTGAACCGTATCGATGAAGTCGTGGTCTTCCATGGCCTGGAAGCCC
AGCACATCGAGTCCATCGCCCGGATCCAGCTCAAGCGGCTGGGCGAGCGTCTCGAGAAGCAGGAGATGCGCCTGGACGTG
TCCGATGCGGCGCTGGCGGAAATCGCACGTTCGGGCTTCGACCCGGTGTTCGGCGCCCGGCCGCTCAAGCGAGCCATCCA
GCAGCAGATCGAGAATCCGGTCGCCAAGCTGATTCTCGAAGGCGTGTTCGGACCGCGCGATGTGGTGCCGGTCGACTGGC
AGGACGGCAAGTTCGTCTTCACGCGCACTTTGCAATAA

Protein sequence :
MRFDKLTTKFQQALADAQSLAARNDHPYIEPVHVLAALLGDPDSGAASLLARAGVAVNRVQPAIDSALKGLPQVQGDDNV
QVGRELQSVLVRTDKEAARRGDTYIASELFLLALADDKGDAGRILREAGLQKKALEAAIDAVRGGENVSGAEGESNREAL
SKYTLDLTERARQGKLDPVIGRDDEIRRTIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNDEVPETLRGKRVLSLD
LAALLAGAKFRGEFEERLKAVLKELAQDDGQNIVFIDELHTMAGAGKAEGAMDAGNMLKPALARGELHCIGATTLDEYRK
YIEKDAALERRFQKVLVGEPDVESTIAILRGLQERYELHHGVEITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAGARI
RMEIDSKPEVMDRLDRRIIQLKIEREAVKKETDDASMRRLAVIEEELEKLQREYNDYEEIWKAEKAAVQGTQAIKEEIDR
VRAEMAELQRKGQFDKLAELQYGKLPELEARLKAADSAEREAGESDSGKPRLLRTQVGAEEIAEVVSRATGIPVAKMMQG
ERDKLLRMEDFLHKRVVGQDEAVRLVSDAIRRSRAGLADPSRPYGSFLFLGPTGVGKTELTRALADFLFDSEEHMIRIDM
SEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTVI
VMTSNLGSQHIQSMAGKPYEVIKEVVWDELKHTFRPEFLNRIDEVVVFHGLEAQHIESIARIQLKRLGERLEKQEMRLDV
SDAALAEIARSGFDPVFGARPLKRAIQQQIENPVAKLILEGVFGPRDVVPVDWQDGKFVFTRTLQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 5e-90 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 4e-90 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB NP_879972.1 ATP-dependent protease, ATPase subunit VFG2076 Protein 8e-97 44