Gene Information

Name : lysS (BP1102)
Accession : NP_879883.1
Strain : Bordetella pertussis Tohama I
Genome accession: NC_002929
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1151365 - 1152885 bp
Length : 1521 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGACCGACCAATCGCCCGCCCCGACCGCCCAGGATGAAAACCGCTTGATCGCCGAACGGCGCGCCAAGCTGGCCAGACT
GCGTGAAACCGGCGTTGCGTTCCCCAACAATTTCGTGCCCGATGCGCACGCCGCCGACCTGCACGCCAGGTACGACGGCC
TGGACCAGGAGGCGCTGACGGCCGCGGCGGTCACGGTCAAGGTGGCCGGCCGCATGATGCTCAAGCGCGTCATGGGCAAG
GCCAGCTTCGCCACGCTGCAGGACGGCAGCGGCCGCATCCAGATCTACCTCGAGCGCGGCACGCTCGGCGAAGAGGCCTA
CGCCGCTTTCAAGCAATGGGACATCGGCGACATCATCGCCATCGAGGGGCCGGTCTTCAAGACCAACAAGGGCGAGCTGT
CGGTGCACGCCAACTCGGCGCGCCTGCTGTCGAAGTCGCTGCGTCCGCTGCCCGACAAGTTCCATGGCGTGGCCGACCAG
GAGCTGCGCTACCGCCAGCGCTACGTCGACCTCATCATGACCGACGCCACCCGCCGCACCTTCGAGGCGCGCAGCAAGGC
CGTCGGCGGCATCCGCCAGGCCATGCTCAATGCGGGCTTTCTCGAAGTCGAGACGCCGATGCTGCACCCGATTCCCGGTG
GCGCGGCGGCCAAGCCCTTCGTGACCCACCACAATGCGCTGGACATGCAGATGTTCCTGCGCATCGCGCCCGAGCTTTAC
CTCAAGCGCCTGATCGTCGGCGGCTTCGAGCGCGTGTTCGAAATCAACCGCAACTTCCGCAACGAGGGGGTGAGCCCGCG
CCACAACCCCGAGTTCACCATGATGGAGTTCTACGCCGCGTACGCCGACTATCGCTGGCTGATGGACTTCACCGAGGACC
TGATCCGCCAGGCCGCGATCGCGGCCACCGGCAGCGCCGTGCTCAGCTACCAGGACCGCGAGCTGGACCTGTCCCAGCCG
TTCGACCGCCTGACGATCTGCGAAGCCATCCTGAAGTACGCCGAGGGCTATACCCAGGCGCAGCTCGACGACCCCGCGTT
CGTGCGCGCCGAGCTCAGGAAACTGGGAGCCAACGTCGAGGGTCCGCCGCTGGCGCGCGCCGGCCTGGGCGCGCTGCAAC
TGGCGCTGTTCGAGGAAACCGCCGAAGCCAAGCTGTGGCGCCCCACCTACATCATCGACTACCCGGTCGAGGTCTCGCCC
CTGGCGCGCGCCTCCGACACCCGCGACGGCATTACCGAGCGCTTCGAACTGTTCATCACCGGACGCGAAATCGCCAACGG
CTTCTCCGAGCTCAACGACCCTGAAGACCAGGCCGAGCGTTTCCGCGCCCAGGTCGAGGCCAAGGACGCCGGCGACGAAG
AAGCCATGTACTTCGACGCCGACTACATCCGCGCGCTCGAATACGGCATGCCCCCCACCGGCGGCTGCGGCATCGGCATC
GACCGCCTGGTCATGCTGCTGACCGACAGCCCCAGCATCCGCGACGTCATCCTCTTCCCGCACCTGCGCCGGGAAGACTG
A

Protein sequence :
MTDQSPAPTAQDENRLIAERRAKLARLRETGVAFPNNFVPDAHAADLHARYDGLDQEALTAAAVTVKVAGRMMLKRVMGK
ASFATLQDGSGRIQIYLERGTLGEEAYAAFKQWDIGDIIAIEGPVFKTNKGELSVHANSARLLSKSLRPLPDKFHGVADQ
ELRYRQRYVDLIMTDATRRTFEARSKAVGGIRQAMLNAGFLEVETPMLHPIPGGAAAKPFVTHHNALDMQMFLRIAPELY
LKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYADYRWLMDFTEDLIRQAAIAATGSAVLSYQDRELDLSQP
FDRLTICEAILKYAEGYTQAQLDDPAFVRAELRKLGANVEGPPLARAGLGALQLALFEETAEAKLWRPTYIIDYPVEVSP
LARASDTRDGITERFELFITGREIANGFSELNDPEDQAERFRAQVEAKDAGDEEAMYFDADYIRALEYGMPPTGGCGIGI
DRLVMLLTDSPSIRDVILFPHLRRED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-129 58
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 2e-75 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS NP_879883.1 lysyl-tRNA synthetase VFG1668 Protein 7e-130 58