Gene Information

Name : tktA (BP0999)
Accession : NP_879793.1
Strain : Bordetella pertussis Tohama I
Genome accession: NC_002929
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1043602 - 1045638 bp
Length : 2037 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGAGCAACCCGACCGCCCCTAAACTTGCCTTGGCGGATGCCATCCGCGTACTTGCGATGGACGCCGTGCAGAAAGCGAA
TTCCGGACACCCCGGCGCGCCCATGGGAATGGCCGAAATCGCGCAAGCGCTGTGGCTGGGCAACCTGCGCCACAACCCGG
CCGATCCGGCCTGGGCCAACCGCGACCGCTTCGTGCTGTCCAATGGCCACGGCTCGATGCTGATCTACGCCCTGCTGCAC
CTGACGGGCTACGATCTGCCCCTGGAAGAGCTGAAGAACTTCCGCCAGCTGCATTCGCGCACGCCGGGGCACCCCGAAGT
GGGCATCACCCCGGGCGTGGAAACCACCACCGGCCCACTGGGCCAGGGCCTGGCCAACGCGGTCGGCATGGCGCTGGCCG
AGGCCCTGCTGGCGGCCGAATTCAACCGCGCCGGCCACACGGTGGTGGACCACCACACCTATGTCTTCCTGGGCGACGGC
TGCCTGATGGAAGGCATCTCGCACGAGGCCTGCTCGCTGGCCGGCACGCTCAAGCTGTCCAAGCTGGTGGCGCTGTACGA
CGACAACGGCATTTCCATCGACGGCCATGTCGAGCACTGGTTCGCCGACGACACGGCGACCCGCTTCGAGGGCTACGGCT
GGAACGTGATCCGCGGCGTGGACGGCCACGACGTGGCGGCGGTGGACGCGGCCATCAAGCAGGCGCGCGCGCAATCCGAG
AAACCCACCCTGATCGTCTGCCGCACCGTGATCGGCAAGGGTTCGCCCAACATGGCCGGCACGCACAATGTGCACGGCGC
GCCGCTGGGCAACGACGAGATCGCCGCCACCCGCGCGGCGCTGGGCTGGTCGGCCGGCCCCTTCGAGGTGCCGCAGGATA
TCTACGCCGCGTGGGACAGCCGTCCCGCCGGCGCGCTGGCGCAGGCCGCCTGGGAAGACAAGTTCCAGGCCTATGCGGCC
CAGTATCCGGCCGAGGCCGCCGAATTCACGCGCCGCATGAAGGGCGAGCTGCCCGAAGGCTTCGCCGCCCGGTTCGAGGC
TTTCCTGCAGGCCACCGTGGCCAAGGGCGAGACGGTCGCCACCCGCAAGGCGTCGCAGTTCGCCATCGCCGAGCTGGCCG
GCCTGCTGCCGGAGATGCTGGGCGGCTCGGCCGACCTGACCGGTTCGAACTTCACCGACTGGAAGGGCGTGGCGCCGCTG
CGCGCCGGCCACCACGGCGTGCATTTCGGCCGCCATATCAACTACGGCGTGCGCGAGTTCGGCATGGCCGCCATCATGAA
CGGCATCGCGCTGCATGGCGGCTACCTGCCGTTCGGCGGCACCTTCCTGACGTTCTCGGACTACTCGCGCAACGCCATCC
GCATGGCGGCGCTGATGAAGCAGCGCGTGGTGCACGTGTTCACGCACGATTCCATCGGCCTGGGCGAGGACGGTCCGACC
CACCAGTCGATCGAACACGCCGCCAGCCTGCGCCTGATTCCCAACCTGTCGGTGTGGCGGCCCTGCGACACCGTCGAGAC
GGCCGCCGCCTGGGGCGCGGCCGTGACGCGGCCGGCCAGCATCGGCATGGACTTGCACGACGGCGGTCCGACCGCGCTGC
TGCTGTCGCGCCAGAACCTGCCGTTCGTGGCGCGCGACGAGGCCACGCAGAAAGCGATTGTTCGCGGTGGTTACGTCTTG
CGCGACGCACACGACGCGCGTGCGGCTATCATCGCCACGGGCTCGGAAGTCGCCATCGCGCTGGCCGCGCAGGAATTGCT
GGCCGCCGACGGCATCGCCGTGCGGGTGGTTTCCATGCCCAGCACCGACGTGTTCGACCGCCAGGACGCCGAATGGAAGC
GCGAAGTGCTGCCGGCCGGCATGCCGCGCGTGGCCGTCGAGGCGGGCGTGACCGCGTTCTGGCACAAGTACGTGGGCCTG
GAAGGCGCCGTGGTGGGTATCGACCGCTATGGCGAGTCGGCGCCCGCCGGGGCTTTGTTCAAATTCTTCGGACTGACCGC
TGAAAAGGTGGCCGAGGCCGTCAAGCAGGTTTTGTAA

Protein sequence :
MSNPTAPKLALADAIRVLAMDAVQKANSGHPGAPMGMAEIAQALWLGNLRHNPADPAWANRDRFVLSNGHGSMLIYALLH
LTGYDLPLEELKNFRQLHSRTPGHPEVGITPGVETTTGPLGQGLANAVGMALAEALLAAEFNRAGHTVVDHHTYVFLGDG
CLMEGISHEACSLAGTLKLSKLVALYDDNGISIDGHVEHWFADDTATRFEGYGWNVIRGVDGHDVAAVDAAIKQARAQSE
KPTLIVCRTVIGKGSPNMAGTHNVHGAPLGNDEIAATRAALGWSAGPFEVPQDIYAAWDSRPAGALAQAAWEDKFQAYAA
QYPAEAAEFTRRMKGELPEGFAARFEAFLQATVAKGETVATRKASQFAIAELAGLLPEMLGGSADLTGSNFTDWKGVAPL
RAGHHGVHFGRHINYGVREFGMAAIMNGIALHGGYLPFGGTFLTFSDYSRNAIRMAALMKQRVVHVFTHDSIGLGEDGPT
HQSIEHAASLRLIPNLSVWRPCDTVETAAAWGAAVTRPASIGMDLHDGGPTALLLSRQNLPFVARDEATQKAIVRGGYVL
RDAHDARAAIIATGSEVAIALAAQELLAADGIAVRVVSMPSTDVFDRQDAEWKREVLPAGMPRVAVEAGVTAFWHKYVGL
EGAVVGIDRYGESAPAGALFKFFGLTAEKVAEAVKQVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 61
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 5e-174 58