Gene Information

Name : lysS (BPP2045)
Accession : NP_884303.1
Strain : Bordetella parapertussis 12822
Genome accession: NC_002928
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 2183879 - 2185399 bp
Length : 1521 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGACCGACCAATCGCCCGCCCCGACCGCCCAGGATGAAAACCGCTTGATCGCCGAACGGCGCGCCAAGCTGGCCAGACT
GCGTGAAACCGGCGTTGCGTTCCCCAACGATTTCGTGCCCGATGCGCACGCCGCCGACCTGCACGCCAGGTACGACGGCC
TGGACCAGGAGGCGCTGACGGCCGCGGCGGTCACGGTCAAGGTGGCCGGCCGCATGATGCTCAAGCGCGTCATGGGCAAG
GCCAGCTTCGCCACGCTGCAGGACGGCAGCGGCCGCATCCAGATCTACCTCGAGCGCGGCACGCTCGGCGAAGAGGCCTA
CGCCGCTTTCAAGCAATGGGACATCGGCGACATCATCGCCATCGAGGGGCCGGTCTTTAAGACCAACAAGGGCGAGCTGT
CGGTGCACGCCAACTCGGCGCGCCTGCTGTCGAAGTCGCTGCGTCCGCTGCCCGACAAGTTCCATGGCGTGGCCGACCAG
GAGCTGCGCTACCGCCAGCGCTACGTCGACCTCATCATGACCGACGCCACCCGCCGCACCTTCGAGGCGCGCAGCAAGGC
CGTCGGCGGCATCCGCCAGGCCATGCTCAATGCGGGCTTTTTCGAAGTCGAGACGCCGATGCTGCACCCGATTCCCGGTG
GCGCGGCGGCCAAGCCCTTCGTGACCCACCACAATGCGCTGGACATGCAGATGTTCCTGCGCATCGCGCCCGAGCTTTAC
CTCAAGCGCCTGATCGTCGGCGGCTTCGAGCGCGTGTTCGAAATCAACCGCAACTTCCGCAACGAGGGGGTGAGCCCGCG
CCACAACCCCGAGTTCACCATGATGGAGTTCTACGCCGCGTACGCCGACTATCGCTGGCTGATGGACTTCACCGAGGACC
TGATCCGCCAGGCCGCGATCGCGGCCACCGGCAGCGCCGTGCTCAGCTACCAGGACCGCGAGCTGGACCTGTCCCAGCCG
TTCGACCACCTGACGATCTGCGAAGCCATCCTGAAGTACGCCGAGGGCTATACCCAGGCGCAGCTCGACGACCCCGCGTT
CGTGCGCGCCGAGCTCAGGAAACTGGGAGCCAACGTCGAGGGTCCGCCGCTGGCGCGCGCCGGCCTGGGCGCGCTGCAAC
TGGCGCTGTTCGAGGAAACCGCCGAAGCCAGGCTGTGGCGCCCCACCTACATCATCGACTACCCGGTCGAGGTCTCGCCC
CTGGCGCGCGCCTCGGACACCCGCGACGGCATTACCGAGCGCTTCGAACTGTTCATCACCGGACGCGAAATCGCCAACGG
CTTCTCCGAGCTCAACGACCCTGAAGACCAGGCCGAGCGTTTCCGCGCCCAGGTCGAGGCCAAGGACGCCGGCGACGAAG
AAGCCATGTACTTCGACGCCGACTACATCCGCGCGCTCGAATACGGCATGCCCCCCACCGGCGGCTGCGGCATCGGCATC
GACCGCCTGGTCATGCTGCTGACCGACAGCCCCAGCATCCGCGACGTCATCCTCTTCCCGCACCTGCGCCGGGAAGACTG
A

Protein sequence :
MTDQSPAPTAQDENRLIAERRAKLARLRETGVAFPNDFVPDAHAADLHARYDGLDQEALTAAAVTVKVAGRMMLKRVMGK
ASFATLQDGSGRIQIYLERGTLGEEAYAAFKQWDIGDIIAIEGPVFKTNKGELSVHANSARLLSKSLRPLPDKFHGVADQ
ELRYRQRYVDLIMTDATRRTFEARSKAVGGIRQAMLNAGFFEVETPMLHPIPGGAAAKPFVTHHNALDMQMFLRIAPELY
LKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYADYRWLMDFTEDLIRQAAIAATGSAVLSYQDRELDLSQP
FDHLTICEAILKYAEGYTQAQLDDPAFVRAELRKLGANVEGPPLARAGLGALQLALFEETAEARLWRPTYIIDYPVEVSP
LARASDTRDGITERFELFITGREIANGFSELNDPEDQAERFRAQVEAKDAGDEEAMYFDADYIRALEYGMPPTGGCGIGI
DRLVMLLTDSPSIRDVILFPHLRRED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 7e-129 58
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 4e-75 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS NP_884303.1 lysyl-tRNA synthetase VFG1668 Protein 4e-129 58