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Name : hpaE (BB0736) Accession : NP_887286.1 Strain : Bordetella bronchiseptica RB50 Genome accession: NC_002927 Putative virulence/resistance : Unknown Product : 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : 1.2.1.- Position : 771067 - 772536 bp Length : 1470 bp Strand : + Note : Similar to Escherichia coli 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase HpaE SWALL:Q46979 (EMBL:Z37980) (488 aa) fasta scores: E(): 7.9e-133, 67.82% id in 488 aa, and to Salmonella typhimurium 4-hydroxyphenylacetate catabolism HpaE or Stm DNA sequence : ATGCGGATTGAACATCTGATCGACGGCAAGGCCGTCGCCGGCAAGCAGTACTTCGAGACCATCAACCCGGCCACGCAGGA GACGCTGGCGGAGGTTGCCGCCGGGGGCGAGGCCGAGGTGCACGCCGCGGTCGCGGCGGCCAAGGCGGCGTTTCCGAAGT GGGCCGGCCTGCCGGCCGCCGAGCGCGCGCGCCTGGTGCGCAAGCTGGGCGACCTGATCGCCGCCCACGTGCCCGAGATC TCGCGCACCGAGACCAACGATTGCGGCCAGACCATCGCGCAGACCGGCAAGCAGCTGGTGCCGCGCGCGGCCGACAATTT CTATTATTTCGCCGAGATGTGCACGCGGGTCGATGGCCATACCTATCCCACGCCCACGCACCTGAACTACACGCTGTACC ACCCGGTGGGCGTGTGCGCGCTGATCAGCCCCTGGAACGTGCCGTTCATGACCGCGACCTGGAAGGTCGCGCCGTGCCTG GCGTTCGGCAACACCGCCGTGCTGAAGATGAGCGAGCTTTCGCCGCTGACCGCGGCGCGCCTGGGCGAGCTGGCGCTGGA GGCGGGCATCCCGCCGGGCGTGCTCAACCTGGTGCACGGCTACGGCCGCGACGCCGGCGAGCCGCTGGTGGCGCACCCGG ACGTGCGCGCCGTGTCCTTCACGGGCTCGACGGCCACCGGCAACCGCATCGTGCAGGCGGCCGGGCTGAAGAAGTTCAGC ATGGAACTGGGCGGCAAGAGCCCGTTCGTGATCTTCGACGACGCCGACCTGGACCGGGCGCTCGACGCGGCGATCTTCAT GATCTTCTCCAACAACGGCCAGCGCTGCACGGCCGGCAGCCGCATCCTGGTGCAGCAAAGCATCTACGCCGATTTCACCC AGAAGTTCGTCGAGCGCGCGCGCCGCATCCGCGTCGGCGACCCGCTGGACGAGGGCACCATCGTCGGGCCGCTGATCAGC CCGGCCCACCTGGCCAAGGTGCGCGGCTATATCGAGCTGGGCAGCAAGGAAGGCGCCACCATGCTGTGCGGCGGGCTGGA CCGCCCGTCGTACGCACCCGAGCTGGATGCGCGCGTGCGCGACGGCAACTTCGTCTGGCCCACGGTGTTCGCCGACGTCG ACAACCGCATGAAGATCGCCCAGGACGAGATCTTCGGGCCGGTCGCCTGCCTGATTCCGTTTCGCGACGAGGCCCACGCC ATCGAGCTGGCCAACGACATCGAGTACGGCCTGTCGAGCTATGTCTGGACCGAGAGCGTCGGCCGCGCGCACCGCGTGGC GGCCGCCATCGAGGCCGGCATGTGCTTTGTCAACAGCCAGAACGTGCGCGACCTGCGCCAGCCGTTCGGCGGCACCAAGG CCTCGGGCACCGGCCGCGAGGGTGGCACCTGGAGCTACGAAGTGTTCTGCGAGCCGAAGAACGTCGCGGTGTCGCTGGGC AATCATCACATTCCGCACTGGGGAGCATGA Protein sequence : MRIEHLIDGKAVAGKQYFETINPATQETLAEVAAGGEAEVHAAVAAAKAAFPKWAGLPAAERARLVRKLGDLIAAHVPEI SRTETNDCGQTIAQTGKQLVPRAADNFYYFAEMCTRVDGHTYPTPTHLNYTLYHPVGVCALISPWNVPFMTATWKVAPCL AFGNTAVLKMSELSPLTAARLGELALEAGIPPGVLNLVHGYGRDAGEPLVAHPDVRAVSFTGSTATGNRIVQAAGLKKFS MELGGKSPFVIFDDADLDRALDAAIFMIFSNNGQRCTAGSRILVQQSIYADFTQKFVERARRIRVGDPLDEGTIVGPLIS PAHLAKVRGYIELGSKEGATMLCGGLDRPSYAPELDARVRDGNFVWPTVFADVDNRMKIAQDEIFGPVACLIPFRDEAHA IELANDIEYGLSSYVWTESVGRAHRVAAAIEAGMCFVNSQNVRDLRQPFGGTKASGTGREGGTWSYEVFCEPKNVAVSLG NHHIPHWGA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hpaE | AAO17179.1 | HpaE | Not tested | tcd island | Protein | 1e-143 | 68 |
| ORF SG19 | AAN62241.1 | putative aldehyde dehydrogenase | Not tested | PAGI-3(SG) | Protein | 5e-55 | 42 |
