Gene Information

Name : thiC (BB0304)
Accession : NP_886853.1
Strain : Bordetella bronchiseptica RB50
Genome accession: NC_002927
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 307181 - 309094 bp
Length : 1914 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAACGCCAACCCCAAGTTCCTGGCCGCCACGGCCGAGGTCGACGCAGCCGCCGTCGCGCCGTTGCCCAAATCCCGCAA
AGTCTACGAAACCGGCTCGCGCCCGGATATCCGCGTGCCGTTTCGCGAGATCGAGCAGGCCGACACGCCCACCATGTTCG
GCGGCGAGAAGAACCCGCCCCTGACCGTCTACGATACCAGCGGCCCGTACACCGACCCGCAGGCCAGCATCGACATCCGC
CGCGGCCTGCCGGCCCTGCGCCGGGCCTGGATCGAAGAACGCGGCGACACCGAAGTGCTGGATGGCCCGACCAGCGACTA
CGGCAAGGAGCGCCTGACCGATCCGAAGCTGACGGCGATGCGCTTCGACCTGCAGCGCCCCCCGCGCCGCGCGCGCGCCG
GCGCCAACGTGACGCAGATGCACTATGCGCGCCGCGGCATCGTCACGCCCGAAATGGAATTCATCGCGCTGCGCGAAAAC
CTGCGCCGCGAACACTACCTGGAAACGCTGCGCGCCAGCGGCCCGGATGGCGAGAAACTGGCCAAGCGCCTGCTGCGCCA
GCACCCCGGCCAGTCGTTCGGCGCCGCCCTCCCGTCGGCCATCACGCCCGAATTCGTCCGCGAGGAAGTCGCGCGCGGCC
GCGCCATCATCCCGGCCAACATCAACCACCCGGAAATCGAACCGATGATCATCGGCCGCAATTTCCTGGTGAAGATCAAC
GCCAACATCGGCAACTCGGCCGTCAGCTCCGGCATCGGCGAGGAAGTCGAGAAGATGACCTGGGCGATCCGCTGGGGCGG
CGATACGGTCATGGACCTGTCGACCGGCAAGCACATCCACGAAACGCGCGAATGGATCATCCGCAATTCGCCGGTGCCGA
TCGGCACGGTGCCGATCTACCAGGCGCTGGAGAAGGTCGACGGCAAGGCCGAGGAACTGACCTGGGAAATCTTCCGCGAC
ACGCTGATCGAGCAGGCCGAGCAAGGCGTGGACTACTTCACGATCCATGCCGGCGTGCGCCTGCCCTTCATCCCCATGAC
GGCCGACCGCATGACCGGCATCGTCTCGCGCGGCGGCTCGATCATGGCCAAGTGGTGCCTGGCGCACCACAAGGAGAGCT
TCCTGTACGAGCGCTTCGAGGAAATCTGTGAAATCATGAAGGCCTACGACGTCAGCTTCTCGCTGGGCGACGGCCTGCGC
CCCGGCTCGGGCTACGACGCCAACGACGAGGCGCAGTTCGCCGAGCTCAAGACCCTGGGCGAGCTGACCCAGGTGGCCTG
GAAGCACGACGTGCAGGTCATGATCGAAGGCCCCGGCCACGTGCCGATGCAGATGATCAAGGAAAACATGGAACTGCAGC
TCAAGCATTGCGACGAGGCGCCGTTCTATACCCTGGGCCCGCTGACCACCGACATCGCGCCCGGCTACGACCACATCACC
TCGGGCATCGGCGCGGCCCTGATCGGCTGGTACGGCACGGCCATGCTGTGCTACGTGACGCCCAAGGAGCACCTGGGCCT
GCCCAACAAGAAGGACGTCAAGGACGGCATCATCACCTACAAGATCGCCGCCCATGCCGCCGACCTGGCCAAGGGACATC
CGGGCGCGGCCATCCGCGACAACGCACTGTCGAAGGCGCGCTTCGAGTTCCGCTGGGACGACCAGTTCAACCTGGGCCTG
GATCCGGACACCGCCAAGGAGTTCCACGACGAGACCCTGCCCAAGGACTCGATGAAAGTGGCGCACTTCTGCTCGATGTG
CGGGCCGCATTTCTGCAGCATGAAGATCACGCAGGATGTGCGCGACTATGCCGCGGCGCAGGGCGTCAGCGAAAAGGACG
CGCTGCAGCAGGGCATGCAGGAAAAGGCGGTGGAGTTCGTCAAGAAGGGCGCCGAGGTCTATCACCGGACCTGA

Protein sequence :
MNANPKFLAATAEVDAAAVAPLPKSRKVYETGSRPDIRVPFREIEQADTPTMFGGEKNPPLTVYDTSGPYTDPQASIDIR
RGLPALRRAWIEERGDTEVLDGPTSDYGKERLTDPKLTAMRFDLQRPPRRARAGANVTQMHYARRGIVTPEMEFIALREN
LRREHYLETLRASGPDGEKLAKRLLRQHPGQSFGAALPSAITPEFVREEVARGRAIIPANINHPEIEPMIIGRNFLVKIN
ANIGNSAVSSGIGEEVEKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEELTWEIFRD
TLIEQAEQGVDYFTIHAGVRLPFIPMTADRMTGIVSRGGSIMAKWCLAHHKESFLYERFEEICEIMKAYDVSFSLGDGLR
PGSGYDANDEAQFAELKTLGELTQVAWKHDVQVMIEGPGHVPMQMIKENMELQLKHCDEAPFYTLGPLTTDIAPGYDHIT
SGIGAALIGWYGTAMLCYVTPKEHLGLPNKKDVKDGIITYKIAAHAADLAKGHPGAAIRDNALSKARFEFRWDDQFNLGL
DPDTAKEFHDETLPKDSMKVAHFCSMCGPHFCSMKITQDVRDYAAAQGVSEKDALQQGMQEKAVEFVKKGAEVYHRT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 74
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 74
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 73