Gene Information

Name : wcbA (BB2923)
Accession : NP_889459.1
Strain : Bordetella bronchiseptica RB50
Genome accession: NC_002927
Putative virulence/resistance : Virulence
Product : capsular polysaccharide export protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3563
EC number : -
Position : 3100569 - 3102626 bp
Length : 2058 bp
Strand : -
Note : ortholog of Bordetella pertussis (BX470248) BP1631

DNA sequence :
ATGATCGAGCTTCATTCGTCAGGCATCGCGCGTATTCCGTACCTGACGGAGCTGCTGGGCGCGCCGGTCACCCGCTACCG
GCGCTTCTGGCCGCCGGGCGGCGCGGCGCCGCGCGCGGTGGCGGGATGGGGCGCGCGCCCCAGCGCCGCGCCGGCGCGGC
GCCGCGCCCGTTCGCTGGGCGTGCCCTACATTGCGCTGGAAGACGGTTTCCTGCGCTCGTTCGGCACCGGGCGCCATTTT
CCGCCTCTGTCGCTGGTGGTCGATCGCCTGGGCATCTACTACGACGCGACGCGCGAATCCGAGCTGGAGTGCCTGCTGGC
GTCGTCGCGCACGCTGCTCGACGGCATCGAGGACGCCGTGCCCGAAGCCATGGAGCTGGTGCGCGAACGCCGCCTGTCGA
AGTACAACCAGGGCGGCTTCCTGGCCACCGGCGTGCCGGCCGACGGCCGGCGCCGGGTGCTGGTGGTGGACCAGACCGAA
GGCGACATGAGCGTGACCCTGGGTTGCGCCGAGGCGGCCACCTTCGAGGCCATGCTGGCGGCGGCGCGGGCGGAGAACCC
TGGCGCGCTGATCTGCGTCAAGACGCATCCCGAGGTGGCGGCCGGCGACAAGTCGGGCTATCTGTCGCGGGTTACCGACG
ACGCCGATACGGTGGCGCTGCGCCACGACATGAATCCCCTGGCCTTGCTGGAACAGATGGACCGGGTCTATGTGGTCAGT
TCGCAGATGGGGTTCGAAGCCCTGATGCTGGACAAGCCCGTGACCTGCTTCGGCATGCCCTGGTATGCCGGCTGGGGCGT
GACCGACGATCGCCAGCGCTGCGAGCGGCGCGGCCGCGCGCGCAGCGTCGAGGAGCTGTTCGCCGGCGCGTATTTCCACT
ACACCCGCTACCTGGATCCGGTGCTGCATCGCCGCGGCACGATCTTCGACGTGATCGACTGGCTGACGCGCCAGCGCGAC
ATGGCGCAGCGCCTGCCGTCGCGCGTGATCGGCGTGGGCATGCGCCGCTGGAAGGCGGCCGCGCTGGCGCCCATTCTGGC
GTTAAAGCCCGGCCAGGCGGTGTTCGCCGCCGACGCCGCCCGCGCGCGGGACCTGCGGCCGGCCGCGGGCGACGCCCTGG
TGCATTGGGGCGCCCGGGCGCCCGCCGGCGTGGCCGAGCTGGCCGAACAGAGCGGTTGCGCGGTGCTGGCCGTGGAGGAT
GGCTTCCTGCGGTCGGTCGGCCTGGGGTCGGACCTGATCCGGCCGCTGAGCCTGGCGCTGGACGGGCGGGGCATCTACTT
CGACCCCCGCCAGCCCAGCGATCTGGAGCATGAATTGAACCGGGGCGGGTTCAGCCCGGGAGAGCTGGCCAGCGCGGCGC
GCATCCGCGCGCTGGTGGTCGCCCACGGCATCACCAAGTACAACGTGGCGCAGCCCCAGCCGGCCGACTGGCCGGCGCGC
GGGCGCGAGATCGTGCTGGTGCCCGGCCAGGTCGAGGACGATGCGTCGGTGCGGCTGGGCTGCGACGAAGTCCGCACCAA
CCTGGACCTGCTGGCGGCCGCGCGCGCCGCGCATCCCGACGCCTACATCGTCTACAAGCCGCATCCGGACGTGGTCAGCC
GCAACCGCCGCGGCCGCGTGGCGCTGCGCGAGGCGCGCCGCCATGCCGATCATGTCGAGTCCGCGCTGTCGGTGGTCAGC
TGCATCCAGGCGTGCGACGTGGTGCACACCATGACCTCGCTGACGGGCTTCGACGCCTTGCTGCGCGGCAAGCGCGTGGT
GACGTACGGCAAGCCGTTCTATGCCGGCTGGGGCCTGACCGAGGACCGCGCCGCCGATTGGCCGCGCGGCCGGCGCACCC
GCCGGCTGAGCCTGGACGAGCTGGTCGCCGGCACGCTGCTGCGCTATCCGCTGTACTGGGATTGGGAACTGCGCGGATAC
ACCACGTGCGAGGCGGTGCTGACGCATATTTTCGAGACGCGCGAACGCCTGCAGCGCGAAGGCCGCCTGCAAGGGCTGCG
CGCCGGCTATGCGCGCCGCCAGGTGCGCAAGCTGCAGACATTGTGGCTGGCCCGATGA

Protein sequence :
MIELHSSGIARIPYLTELLGAPVTRYRRFWPPGGAAPRAVAGWGARPSAAPARRRARSLGVPYIALEDGFLRSFGTGRHF
PPLSLVVDRLGIYYDATRESELECLLASSRTLLDGIEDAVPEAMELVRERRLSKYNQGGFLATGVPADGRRRVLVVDQTE
GDMSVTLGCAEAATFEAMLAAARAENPGALICVKTHPEVAAGDKSGYLSRVTDDADTVALRHDMNPLALLEQMDRVYVVS
SQMGFEALMLDKPVTCFGMPWYAGWGVTDDRQRCERRGRARSVEELFAGAYFHYTRYLDPVLHRRGTIFDVIDWLTRQRD
MAQRLPSRVIGVGMRRWKAAALAPILALKPGQAVFAADAARARDLRPAAGDALVHWGARAPAGVAELAEQSGCAVLAVED
GFLRSVGLGSDLIRPLSLALDGRGIYFDPRQPSDLEHELNRGGFSPGELASAARIRALVVAHGITKYNVAQPQPADWPAR
GREIVLVPGQVEDDASVRLGCDEVRTNLDLLAAARAAHPDAYIVYKPHPDVVSRNRRGRVALREARRHADHVESALSVVS
CIQACDVVHTMTSLTGFDALLRGKRVVTYGKPFYAGWGLTEDRAADWPRGRRTRRLSLDELVAGTLLRYPLYWDWELRGY
TTCEAVLTHIFETRERLQREGRLQGLRAGYARRQVRKLQTLWLAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lipA NP_273145.1 capsule polysaccharide modification protein Not tested IHT-A Protein 3e-99 45
kpsC YP_854335.1 capsule polysaccharide export protein KpsC Not tested PAI I APEC-O1 Protein 1e-80 44
kpsC AAZ04470.1 capsule polysaccharide export protein Virulence PAI I APEC-O1 Protein 8e-81 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
wcbA NP_889459.1 capsular polysaccharide export protein VFG0692 Protein 2e-97 47
wcbA NP_889459.1 capsular polysaccharide export protein VFG0704 Protein 1e-89 46
wcbA NP_889459.1 capsular polysaccharide export protein VFG0259 Protein 1e-99 45