Gene Information

Name : aldH (BB2647)
Accession : NP_889184.1
Strain : Bordetella bronchiseptica RB50
Genome accession: NC_002927
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 2807859 - 2809355 bp
Length : 1497 bp
Strand : -
Note : ortholog of Bordetella pertussis (BX470248) BP1858

DNA sequence :
ATGACCCTGCACGATTCCGCCTACTGGCGCGCGCAAGCCGCCGCCCTCGCCCCCGAAGGCCGCGCCTATATCGACGGCGC
CTATTGCGACGCCGCCGATGGCGCCACCTTCGCCGCGCACAGCCCGATCGACGGCCGCAAGCTGGCCGATGTCGCCGCCT
GCGGCGCGGCCGACGTGGACCGCGCGGTGGCCGCCGCGCGCCGCGCCTTCGAGGCCGGCGTCTGGAGCGGCCTGGCCCCG
CGCGAGCGCAAGCACCGCCTGCTGCGCCTGGCCGCGCTGATCACCAAACACCAGGAAGAGCTGGCGCTGCTCGAAACGCT
GGACATGGGCAAGCCGATCCGCGACGCCCTGGCCTTCGACCTGCCCGAGACCGCCCGCTGCTATGCGTGGTACGGCGAAG
CCATCGACAAGCGCTACGACGAGATCGCGCCTACCGGCGCCGACGCGCTGGCCACCATCACGCGCGAGCCGCTGGGCGTG
GTGGCCGCCGTGGTGCCGTGGAATTACCCCTTGATGATGGCGGCCTGGAAAGTGGCCCCGGCGCTGGCCGTGGGCAACAG
CGTCATCCTCAAGCCTGCCGAGCAGGCCTCGCTGTCGGCGCTGCGGCTGGCGGCCCTGGCCGAACAGGCCGGCATCCCGC
CCGGCGTGTTCAGCGTGGTGCCCGGCCTGGGCGCGCAGGCCGGCCAGGCGCTCGGCCTGCACCCGGACGTCGACTGCATC
GCCTTCACCGGCTCGACGGCGACCGGCAAGCGCTTCATGACCTACTCGGGCCAATCCAATCTCAAGCGCGTCTGGCTGGA
GTGCGGCGGCAAGTCGCCCCATATCGTGTTCGCCGACTGCCCCGACCTGGACCGCGCGGCCCAGGTCGCCGCGCTGGCGA
TCTTCTCCAACCAGGGCGAGGTCTGCATCGCCGGTTCGCGCCTGTACGTGCAGCACGGCATCTACGACGCCTTCATGGAA
AAAGTGGCCGCCTTCGCCGCCACCCTGCGCCCCGGCAATCCGCTGGACCCGGACAGCGCGCTGGGCGCCATGGTCGACGA
ACGGCAGACGCAGGCGGTCATGGCCCGCATCGCCGCCGGCGCCCAGGAAGGCGCGCGGCTGCGCCTGGGCGGCCGGCAAG
TGCTGACCAACAGCGGCGGCTACTACATCGAACCGACCATCTTCGATTGTCCCGGCCAGGACAACTCGCTGGTGCGCGAG
GAAATCTTCGGGCCGGTGCTGGCCGCGCAAGGCTTCGCCGACGAGGACGAGGCCGTCGCGCTGGCCAATGATTCCATCTA
TGGGCTGGGGGCCGGGCTGTGGACCGCCGACCTCGGCCGCGCGCACCGCCTGTCGCGCCGCCTGCGCGCCGGGCTGGTAT
GGGTCAACTGCTATGCCGACGGCGACATCACGGTGCCCTTCGGCGGCGTCAAGCAATCCGGCTTCGGGCGCGACAAGTCG
CTGCACGCGATGGACAAGTACAGCGACCTCAAGACCACCTGGATCAGCCTGCGCTGA

Protein sequence :
MTLHDSAYWRAQAAALAPEGRAYIDGAYCDAADGATFAAHSPIDGRKLADVAACGAADVDRAVAAARRAFEAGVWSGLAP
RERKHRLLRLAALITKHQEELALLETLDMGKPIRDALAFDLPETARCYAWYGEAIDKRYDEIAPTGADALATITREPLGV
VAAVVPWNYPLMMAAWKVAPALAVGNSVILKPAEQASLSALRLAALAEQAGIPPGVFSVVPGLGAQAGQALGLHPDVDCI
AFTGSTATGKRFMTYSGQSNLKRVWLECGGKSPHIVFADCPDLDRAAQVAALAIFSNQGEVCIAGSRLYVQHGIYDAFME
KVAAFAATLRPGNPLDPDSALGAMVDERQTQAVMARIAAGAQEGARLRLGGRQVLTNSGGYYIEPTIFDCPGQDNSLVRE
EIFGPVLAAQGFADEDEAVALANDSIYGLGAGLWTADLGRAHRLSRRLRAGLVWVNCYADGDITVPFGGVKQSGFGRDKS
LHAMDKYSDLKTTWISLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 9e-111 57
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-64 44
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-64 44
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-64 44
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-64 44
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-64 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldH NP_889184.1 aldehyde dehydrogenase VFG0082 Protein 6e-65 44