Gene Information

Name : BB2504 (BB2504)
Accession : NP_889043.1
Strain : Bordetella bronchiseptica RB50
Genome accession: NC_002927
Putative virulence/resistance : Resistance
Product : membrane transport ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 2656511 - 2658847 bp
Length : 2337 bp
Strand : -
Note : ortholog of Bordetella pertussis (BX470248) BP2722

DNA sequence :
ATGCCCTCCACGACCCGCGACCTTGCCCTCGATACGCCATCTGGCCAACGCACGGACGCCCACGGCCACGACCACGCAGG
CCACGACCACGCAGGCCATGACCATGCCGGGCACGACCATGCCCACGACCATGGCATCCCGGCCTGCTGCGGCCATGGGC
ACGGCCAGCCGGCCGCGCCCGCGGCCGCCCCGGCCTGGCAGCCCGGTCCCGGCCAGCAGGTCACGCGGGTGCGCATCGGG
CAGATGGACTGCCCCACCGAGGAAACGCTGATCCGCAAGAAGCTGGCCAGCCTGCCCGAGGTGCACGAGCTCGACTTCAA
CCTGATGCAGCGCGTACTGACCGTGCTGCATGCCGACGGCGCGCTCGATCGCATCGACGCGGCGATCCGCTCGCTGGGCA
TGACGCCCGAGCCCCTGGCCGGCGACGCCCCGGCGACCCCGGCCGGCGCGGCCGCGCCTTCGCGCGGCTGGCGCCTGCTG
GCCGCCGGCGGGGTGCTGGCGGCGCTGTCCGAGCTCGCCCACTTCACCGGCCAGCCGGTCTATGTCGCCGCCGCCCTGGC
GCTGGCGGCCATCCTGGCCTGCGGGCTGTCGACCTACCGCAAGGGCTGGATCGCGGTGCGCAACGGCAACCTCAACATCA
ATGCCCTGATGAGCATCGCCGTGACCGGCGCGATGCTCATCGGCCAATGGCCGGAAGCGGCCATGGTGATGTTCCTGTTC
AACGTGGCCGAGCTGATCGAGGCCCGCGCCCTGGACCGCGCCCGCCATGCGGTGCGCGGCCTGCTGGACCTGGCGCCGCA
GACCGCCACCGCGCGCCAGCCGGACGGCTCGTGGGCCGAGGTGCCGGCGGCGCGACTGCGCCCGGGCGACCTGGTGCGGG
TGCGCCCGGGCGAGCGCATCGCCGCCGACGGCACCATCAGCGAAGGCCAGTCCGCGATCGACCAGTCGCCCATCACCGGC
GAAAGCCTGCCGGTGGAAAAAGGCCCGGACGACGACGTCTACGCCGGCACCGTCAATGCCTCCGGGTCGTTCGACTACCG
CGTCACGGCGGCGGCCGGCAATACCACGCTGGACCGCATCATCCACGCGGTCGAACAGGCCCAGGGCGCGCGCGCCCCGA
CCCAGCGCTTCATCGACCGCTTCTCGCGCATCTACACGCCGGCCGTGGTCGGGCTGGCGGTGCTGGTCGCGCTGGCGCCG
CCGCTGCTGCTGGGCCACGCCTGGCTCGACTCCGTGTACCGCGCGCTGGCGCTGCTGATCATCGCCTGCCCCTGCGCGCT
GGTGATTTCCACCCCGGTCAGCGTGGTCAGCGGCCTGACCGCCGCCGCGCGGCGCGGCATCCTGATCAAGGGCGGCGTCT
ACCTGGAGGAAGGACGCAAGCTGCGCTGGCTGGCGCTGGACAAGACTGGCACGCTGACCCAGGGCAAGCCGGTGCAGACC
GACCTGGAACTGCTGCACGACGCCAGCGCGGGCGGGCGCCCGGCGCTGCGCGCCGCGGTCAGCCTGGCGGCGCGCTCGGA
CCACCCCGTGTCGCGCGCGCTGGCCCAGGCCGACCACGCCCTGGACGCGCCGCTGGACGAGGTGAACGGTTTCGCCGCCC
TGCCCGGCCGCGGCGTGCAGGGCGAGATCGGCGGCGAGCGCTTCCAGCTGGGCAACCGCCGCCTGATGCGCGAGCTGGAC
GTCAGCACGCCCGATATCGAGGCCCGCATCGACGCCTATGAAGCGGCCGGCAAGACCGCCATCGCCCTGGCCGACGGGCA
GCGCGTCCTGCTGCTGGCCGCGGTGGCCGACACGCTCAAGGCCAGCAGCGCCGCCGCCGTGGCCGACCTGCACCGGCTGG
GCGTGCGCACCCTCATGCTGACCGGCGACAACACCCGCGCCGCCCAGGCGGTGGCCGCCCAGGCCGGCATCGACGAGGCG
CGCGGCGACCTGCTGCCGCAGGACAAGCTGGACGCCGTCGAGGCCAAGCTGGATCCGGCCCTGCGCGTGGGCATGGTGGG
CGACGGCATCAACGACGCGCCGGCGCTGGCGCGCGCCGACATCGGCTTCGCCATGGGCGCGGCCGGCACCGGCACCGCCA
TCGAAACCGCCGACGTGGCGCTGATGGACGACGACCTGCGCAAGATCGGCACGTTCGTGCGCCTGTCGCGCGCCACCCAC
CGCATCCTGACCCAGAACATCGTCCTGGCGCTGGGCATCAAGGCGGTGTTCCTGGTGCTGGCGATGGCCGGCCAGGCCAC
GCTGTGGATGGCGGTGTTCGCCGACGTCGGCGCCAGCCTGCTGGTGGTCGCCAACGGCTTGCGGCTGCTGCGCGCGGGCA
GGCACCAGGCGTCCTGA

Protein sequence :
MPSTTRDLALDTPSGQRTDAHGHDHAGHDHAGHDHAGHDHAHDHGIPACCGHGHGQPAAPAAAPAWQPGPGQQVTRVRIG
QMDCPTEETLIRKKLASLPEVHELDFNLMQRVLTVLHADGALDRIDAAIRSLGMTPEPLAGDAPATPAGAAAPSRGWRLL
AAGGVLAALSELAHFTGQPVYVAAALALAAILACGLSTYRKGWIAVRNGNLNINALMSIAVTGAMLIGQWPEAAMVMFLF
NVAELIEARALDRARHAVRGLLDLAPQTATARQPDGSWAEVPAARLRPGDLVRVRPGERIAADGTISEGQSAIDQSPITG
ESLPVEKGPDDDVYAGTVNASGSFDYRVTAAAGNTTLDRIIHAVEQAQGARAPTQRFIDRFSRIYTPAVVGLAVLVALAP
PLLLGHAWLDSVYRALALLIIACPCALVISTPVSVVSGLTAAARRGILIKGGVYLEEGRKLRWLALDKTGTLTQGKPVQT
DLELLHDASAGGRPALRAAVSLAARSDHPVSRALAQADHALDAPLDEVNGFAALPGRGVQGEIGGERFQLGNRRLMRELD
VSTPDIEARIDAYEAAGKTAIALADGQRVLLLAAVADTLKASSAAAVADLHRLGVRTLMLTGDNTRAAQAVAAQAGIDEA
RGDLLPQDKLDAVEAKLDPALRVGMVGDGINDAPALARADIGFAMGAAGTGTAIETADVALMDDDLRKIGTFVRLSRATH
RILTQNIVLALGIKAVFLVLAMAGQATLWMAVFADVGASLLVVANGLRLLRAGRHQAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 8e-168 64
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 3e-94 45
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 2e-94 45
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-91 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BB2504 NP_889043.1 membrane transport ATPase BAC0298 Protein 8e-165 63
BB2504 NP_889043.1 membrane transport ATPase BAC0461 Protein 3e-71 43