Gene Information

Name : acoD (BB2388)
Accession : NP_888929.1
Strain : Bordetella bronchiseptica RB50
Genome accession: NC_002927
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 2545584 - 2547113 bp
Length : 1530 bp
Strand : +
Note : ortholog of Bordetella pertussis (BX470248) BP2157

DNA sequence : 
ATGGATCTATCCGACCTGAAAAAATTGGGCCTGGATGTGGCCTACCCGTTCAAGGAACAGTACGAGAACTACATCGGCGG
CCAATGGGTGCCTCCGGTAGGCGCGGAGTACTTCGACAATCTGTCGCCCATTACCGGCCAGCCGTTTTGCCGCGTGCCGC
GCTCGGGCGCGGCCGACATCGAACTGGCGCTGGACGCGGCGCATCGCGCGCGCGCCGCGTGGGCGCGCACCTCGCCCGCC
GAGCGGGCCAACATCCTGCTGCGCATCGCCGACCGCATCGAGGGACAGTTGCCGATGCTGGCGGTTGCCGAGTCGATCGA
CAACGGCAAGCCGCTGCGCGAGACCACCGCGGCCGACCTGCCGCTGGCGATCGACCATTTCCGCTATTTCGCGGGCTGCA
TCCGGGCGCAGGAGGGCGCCATCTCGGAGATCGACGCCAACACCGTGGCCTACCACTTCCACGAACCCATCGGCGTGGTG
GGGCAGATCATTCCCTGGAACTTCCCGCTGCTGATGGCGGCCTGGAAGCTGGCGCCGGCGCTGGCGGCGGGCTGCGTGGT
GGTGCTCAAGCCGGCCGAACAGACGCCGGCCTCGATCCTGGTGCTGGCCGAACTGATCGGCGACCTGCTGCCGCCGGGCG
TGCTCAACGTGGTCAACGGCTATGGCAAGGAGGCCGGCCAGGCGCTGGCCACCAGCAAGCGCATCGCCAAGATCGCCTTC
ACCGGGTCGACGCCGGTGGGCAAGCACATCCTGCACGCGGCGGCCGACAACCTGATCCCCGCCACGGTGGAGCTGGGCGG
CAAGAGCCCCAACATCTTCTTCGACGACGTGATGGACCACGACGACGAGTTCCTGGACAAGGCGCTCGAGGGGCTGGCCA
TGTTCGCGCTCAACCAGGGCGAGGTCTGCACCTGCCCGTCGCGCATCCTGATCCAGGAGTCGATCTACGAGCGCTTCATC
GAGAAGGCCATCGCGCGGGTGCAGTCCATCAAGACCGGCCATCCGCTCGATGCCGGCACCATGGTGGGCGCGCAGGTCTC
GCAGGTGCAGATGGACAAGATCCTGTCCTATATCGATATCGGCCGCCAGGAGGGCGCGCAATGCCTGACCGGCGGCGCGC
GCAACGACATGCTGCCGGGCGGGCTGGACCAGGGTTTCTATGTCCAGCCGACCATGCTGCTGGGCAAGAACAGCATGCGC
ATCTTCCAGGAGGAAATCTTCGGGCCGGTCGCGGCGGTGGCCACCTTCAAGGACGAGGAGGAGGCCATCGCCATGGCCAA
CGACACGTTCTACGGCCTGGGCGCGGGCGTCTGGAGCCGCGACGGCGCGCGGGCCTACCGCGTGGGCCGCGGCATCGAGG
CCGGCCGGGTGTGGACCAATTGCTATCACCTGTATCCGGCGCATGCCGCCTTCGGCGGCTACAAGCAGTCCGGCATCGGG
CGCGAGACGCACAAGGCGGCGCTGTCGAATTACCAGCAGACCAAGTGCCTGCTGGTGAGCTACAGCGCCAAGGCCCTGGG
CTTCTTCTAA

Protein sequence : 
MDLSDLKKLGLDVAYPFKEQYENYIGGQWVPPVGAEYFDNLSPITGQPFCRVPRSGAADIELALDAAHRARAAWARTSPA
ERANILLRIADRIEGQLPMLAVAESIDNGKPLRETTAADLPLAIDHFRYFAGCIRAQEGAISEIDANTVAYHFHEPIGVV
GQIIPWNFPLLMAAWKLAPALAAGCVVVLKPAEQTPASILVLAELIGDLLPPGVLNVVNGYGKEAGQALATSKRIAKIAF
TGSTPVGKHILHAAADNLIPATVELGGKSPNIFFDDVMDHDDEFLDKALEGLAMFALNQGEVCTCPSRILIQESIYERFI
EKAIARVQSIKTGHPLDAGTMVGAQVSQVQMDKILSYIDIGRQEGAQCLTGGARNDMLPGGLDQGFYVQPTMLLGKNSMR
IFQEEIFGPVAAVATFKDEEEAIAMANDTFYGLGAGVWSRDGARAYRVGRGIEAGRVWTNCYHLYPAHAAFGGYKQSGIG
RETHKAALSNYQQTKCLLVSYSAKALGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-142 67
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-149 67
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-149 67
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-149 67
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-148 67

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
acoD NP_888929.1 aldehyde dehydrogenase VFG0082 Protein 1e-142 67