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Name : lysS (BB2293) Accession : NP_888836.1 Strain : Bordetella bronchiseptica RB50 Genome accession: NC_002927 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 2421951 - 2423471 bp Length : 1521 bp Strand : - Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : ATGACCGACCAATCGCCCGCCCCGACCGCCCAGGATGAAAACCGCTTGATCGCCGAACGGCGCGCCAAGCTGGCCAGACT GCGTGAAACCGGCGTTGCGTTCCCCAACGATTTCGTGCCCGATGCGCACGCCGCCGACCTGCACGCCAGGTACGACGGCC TGGACCAGGAGGCGCTGACGGCCGCGGCGGTCACGGTCAAGGTGGCCGGCCGCATGATGCTCAAGCGCGTCATGGGCAAG GCCAGCTTCGCCACGCTGCAGGACGGCAGCGGCCGCATCCAGATCTACCTCGAGCGCGGCACGCTCGGCGAAGAGGCCTA CGCCGCTTTCAAGCAATGGGACATCGGCGACATCATCGCCATCGAGGGGCCGGTCTTCAAGACCAACAAGGGCGAGCTGT CGGTGCACGCCAACTCGGCGCGCCTGCTGTCGAAGTCGCTGCGTCCGCTGCCCGACAAGTTCCATGGCGTGGCCGACCAG GAGCTGCGCTACCGCCAGCGCTACGTCGACCTCATCATGACCGACGCCACCCGCCGCACCTTCGAGGCGCGCAGCAAGGC CGTCGGCGGCATCCGCCAGACCATGCTCAATGCGGGCTTTCTCGAAGTCGAGACGCCGATGCTGCACCCGATTCCCGGTG GCGCGGCGGCCAAGCCCTTCGTGACCCACCACAATGCGCTGGACATGCAGATGTTCCTGCGCATCGCGCCCGAGCTTTAC CTCAAGCGCCTGATCGTCGGCGGCTTCGAGCGCGTGTTCGAAATCAACCGCAACTTCCGCAACGAGGGGGTGAGCCCGCG CCACAACCCCGAGTTCACCATGATGGAGTTCTACGCCGCGTACGCCGACTATCGCTGGCTGATGGACTTCACCGAGGACC TGATCCGCCAGGCCGCGATCGCGGCCACCGGCAGCGCCGTGCTCAGCTACCAGGACCGCGAGCTGGACCTGTCCCAGCCG TTCGACCGCCTGACGATCTGCGAAGCCATCCTGAAGTACGCCGAGGGCTATACCCAGGCGCAGCTCGACGACCCCGCGTT CGTGCGCGCCGAGCTCAGGAAACTGGGAGCCAACGTCGAGGGTCCACCGCTGGCGCGCGCCGGCCTGGGCGCGCTGCAAC TGGCGCTGTTCGAGGAAACCGCCGAAGCCAAGCTGTGGCGCCCCACCTACATCATCGACTACCCGGTCGAGGTCTCGCCC CTGGCGCGCGCCTCCGACACCCGCGACGGCATTACCGAGCGCTTCGAACTGTTCATCACCGGACGCGAAATCGCCAACGG CTTCTCCGAGCTCAACGACCCTGAAGACCAGGCCGAGCGTTTCCGCGCCCAGGTCGAGGCCAAGGACGCCGGCGACGAAG AAGCCATGTACTTCGACGCCGACTACATCCGCGCGCTCGAATACGGCATGCCCCCCACCGGCGGCTGCGGCATCGGCATC GACCGCCTGGTCATGCTGCTGACCGACAGCCCCAGCATCCGCGACGTCATCCTCTTCCCGCACCTGCGCCGGGAAGACTG A Protein sequence : MTDQSPAPTAQDENRLIAERRAKLARLRETGVAFPNDFVPDAHAADLHARYDGLDQEALTAAAVTVKVAGRMMLKRVMGK ASFATLQDGSGRIQIYLERGTLGEEAYAAFKQWDIGDIIAIEGPVFKTNKGELSVHANSARLLSKSLRPLPDKFHGVADQ ELRYRQRYVDLIMTDATRRTFEARSKAVGGIRQTMLNAGFLEVETPMLHPIPGGAAAKPFVTHHNALDMQMFLRIAPELY LKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYADYRWLMDFTEDLIRQAAIAATGSAVLSYQDRELDLSQP FDRLTICEAILKYAEGYTQAQLDDPAFVRAELRKLGANVEGPPLARAGLGALQLALFEETAEAKLWRPTYIIDYPVEVSP LARASDTRDGITERFELFITGREIANGFSELNDPEDQAERFRAQVEAKDAGDEEAMYFDADYIRALEYGMPPTGGCGIGI DRLVMLLTDSPSIRDVILFPHLRRED |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 9e-130 | 58 |
| lysS | YP_005163386.1 | lysyl-tRNA synthetase | Not tested | Not named | Protein | 1e-75 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | NP_888836.1 | lysyl-tRNA synthetase | VFG1668 | Protein | 5e-130 | 58 |
