Gene Information

Name : BB2006 (BB2006)
Accession : NP_888551.1
Strain : Bordetella bronchiseptica RB50
Genome accession: NC_002927
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2144578 - 2145342 bp
Length : 765 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
GTGAGCTTTACCGTCCTGATCCCGGCGCGCCTGGCGTCCACCCGCCTGCCCGACAAGCCGCTGGCCGACATCGCCGGCAA
GCCCATGGTGGTGCGCGTGGCCGAACGCGCCGCGCTGTCGGGCGCCGAGCGCGTCATGATCGCCACCGACGATGCGCGCG
TCCAGCAAGCGGCCGCCGACCATGGCCATGCCGCCATCCTGACCCGTCCCGACCACCCCACCGGCACCGACCGCCTGTCC
GAGGCCGTCGACGCGCTGGGGCTGCCCGATGACGCCATCGTCGTCAACGTACAGGGCGACGAGCCGCTGATCGAACCGGC
CCTGATCGACGCGGTCGCCGCCCAGCTGGTGGCCGCCCCGCATGCCGATATCGCCACCTGTGCCTGTCCGCTGGCCGACG
CCGAGGCGCTGTTCGACCCCAATGTCGTGAAAGTGGTGTGCGCGGCCGACCGGCGCGCCCTGTACTTCTCGCGCGCCCCC
ATCCCGTGGGCGCGCGACGCCCTGGCCGGCGGCGCACGGGTTCTTGCCCCCGGCCTGCCCGCCTGGCATCACATCGGCAT
CTATGCCTATCGCGTGGCCTTCCTGCGCCGTTTCCCGGCCCTGTCGCAGGGACAGCTGGAACGCTACGAATCGCTGGAAC
AGCTGCGCGCGATGGAGCACGGCCACGTTATCGTGGTGCACCATACCGACAGCGCGCCCGCCGCCGGCGTGGACACGCCA
GCCGACCTGGAGCGTGCCCGGGCCGCATACACGAATCGGTTATAA

Protein sequence : 
MSFTVLIPARLASTRLPDKPLADIAGKPMVVRVAERAALSGAERVMIATDDARVQQAAADHGHAAILTRPDHPTGTDRLS
EAVDALGLPDDAIVVNVQGDEPLIEPALIDAVAAQLVAAPHADIATCACPLADAEALFDPNVVKVVCAADRRALYFSRAP
IPWARDALAGGARVLAPGLPAWHHIGIYAYRVAFLRRFPALSQGQLERYESLEQLRAMEHGHVIVVHHTDSAPAAGVDTP
ADLERARAAYTNRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 3e-32 45
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 2e-32 45
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-32 45