Gene Information

Name : bscN (BB1628)
Accession : NP_888173.1
Strain : Bordetella bronchiseptica RB50
Genome accession: NC_002927
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 1729445 - 1730779 bp
Length : 1335 bp
Strand : +
Note : ortholog of Bordetella pertussis (BX470248) BP2245

DNA sequence :
ATGCGTCAGTACCACTACATCACGGAGATGATGCGGGTGGCCCTGCAGGATCTGTCCACGTTGCGGATAAAGGGCCGAGT
GGTGCAAGTGGTGGGAACGATCATCAAGGCCGTCGTTCCGATGGTCAAGATCGGCGAAGTGTGCCTGCTGCGCAATCCTG
GCGAGGACTTCGAGATGCACGGCGAAGTGGTGGGCTTTGTTCGCGACGCCGCCTTGCTCACGCCCATCGGCGACATGTAC
GGGATTTCCTCGGCGACCGAGGTGATACCGACCGGACGCACGCATATGGTGCCCGTCGGTCCGGGCTTGCTGGGACGCGT
GCTGGACGGGCTGGGACGTCCGCTGGACGTCGCCGAGTCAGGGCCGCTGCATGCCCACAAGTTCTATCCGGTCTTCGCCG
ATGCGCCGGATCCGCTGACGCGTCGCATCATCCATGCTCCGCTGGAGCTGGGGGTGCGCGTACTGGACGGTTTGCTTACA
TGCGGGGAAGGCCAGCGTCTGGGAATTTTCGCAGCAGCCGGCGGCGGCAAGTCGACCTTGCTGGGCATGCTGGTCAAGGG
CGCCGCGGTCGACGTGACGGTGGTGGCGCTGATCGGCGAGCGTGGGCGGGAAGTTCGCGAGTTCCTTGAGCACGAACTCG
GTCCGGAGGGCAGACGCAAGAGCGTGATCGTCTGCGCGACCAGCGACAAGTCCTCGATGGAGCGTGCCAAGGCGGCATAC
GTCGCAACCGCCATCGCCGAATACTTCCGCGATCAAGGGCAGCGTGTACTTTTTCTGATGGACTCGGTCACCCGCTTTGC
GCGAGCCCAGCGTGAAATCGGCTTGGCGGCAGGCGAGCCGCCGACGCGGCGCGGCTATCCGCCGTCGGTGTTCGCCACCC
TGCCAAAACTGATGGAGCGCGCCGGCATGAACCAGACGGGTTCGATCACGGCGCTGTATACGGTGCTGGTCGAGGGGGAC
GACATGAACGAACCGGTGGCCGACGAGACGCGTTCGATACTGGACGGCCACATCGTGCTCTCGCGCAAGCTGGGAGCGGC
GAATCACTATCCTGCCGTCGACGTGCTGGCCTCAGCCAGCCGGGTCATGAATGCCGTGGTGTCGCCACGTCACAAGTACC
TGGCCGGACGTATGCGCGAACTGATGGCCAAGTACCAGGACGTCGAGCTGTTGGTGAAAATCGGCGAGTACAAGCAGGGC
GCCGATGCGTCGACCGATGAGGCGATACAGAAGATCGGACAGATCAATGCGTTTCTCAGACAACTAACCGACGAACGCGA
AGCATTCGAGGATACCGTACTGCGCATGGCTGAAATCATCGGACCCGAATCCTAA

Protein sequence :
MRQYHYITEMMRVALQDLSTLRIKGRVVQVVGTIIKAVVPMVKIGEVCLLRNPGEDFEMHGEVVGFVRDAALLTPIGDMY
GISSATEVIPTGRTHMVPVGPGLLGRVLDGLGRPLDVAESGPLHAHKFYPVFADAPDPLTRRIIHAPLELGVRVLDGLLT
CGEGQRLGIFAAAGGGKSTLLGMLVKGAAVDVTVVALIGERGREVREFLEHELGPEGRRKSVIVCATSDKSSMERAKAAY
VATAIAEYFRDQGQRVLFLMDSVTRFARAQREIGLAAGEPPTRRGYPPSVFATLPKLMERAGMNQTGSITALYTVLVEGD
DMNEPVADETRSILDGHIVLSRKLGAANHYPAVDVLASASRVMNAVVSPRHKYLAGRMRELMAKYQDVELLVKIGEYKQG
ADASTDEAIQKIGQINAFLRQLTDEREAFEDTVLRMAEIIGPES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 3e-127 65
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-108 57
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 4e-108 57
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-109 56
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 4e-109 56
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 4e-109 56
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 7e-109 56
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-108 56
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-107 55
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-107 55
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-85 53
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-85 53
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 5e-86 53
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-86 53
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 1e-85 53
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-87 53
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-79 52
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 5e-77 52
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-82 52
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-82 52
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-82 51
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-92 50
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 1e-87 50
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-88 49
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-88 49
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-83 48
escN AAC31513.1 L0034 Virulence LEE Protein 2e-84 47
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-84 47
escN NP_290268.1 hypothetical protein Virulence LEE Protein 3e-84 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 3e-84 47
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-82 47
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 8e-83 47
invC AAS66861.1 InvC Not tested SSR-2 Protein 1e-79 46
escN AAC38383.1 EscN Virulence LEE Protein 4e-84 45
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-72 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 9e-76 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 9e-76 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 9e-76 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 9e-76 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 4e-72 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
bscN NP_888173.1 type III secretion system ATPase VFG0048 Protein 0.0 99
bscN NP_888173.1 type III secretion system ATPase VFG0390 Protein 6e-130 68
bscN NP_888173.1 type III secretion system ATPase VFG0192 Protein 2e-129 65
bscN NP_888173.1 type III secretion system ATPase VFG2144 Protein 2e-104 55
bscN NP_888173.1 type III secretion system ATPase VFG0515 Protein 6e-86 53
bscN NP_888173.1 type III secretion system ATPase VFG0812 Protein 1e-84 47
bscN NP_888173.1 type III secretion system ATPase VFG2459 Protein 1e-82 46
bscN NP_888173.1 type III secretion system ATPase VFG0730 Protein 2e-84 45
bscN NP_888173.1 type III secretion system ATPase VFG2331 Protein 4e-71 45
bscN NP_888173.1 type III secretion system ATPase VFG1254 Protein 2e-80 45
bscN NP_888173.1 type III secretion system ATPase VFG0555 Protein 4e-76 43
bscN NP_888173.1 type III secretion system ATPase VFG1008 Protein 3e-75 43
bscN NP_888173.1 type III secretion system ATPase VFG1778 Protein 4e-75 43
bscN NP_888173.1 type III secretion system ATPase VFG2499 Protein 2e-71 42