Gene Information

Name : nrdF (MYPU_5390)
Accession : NP_326370.1
Strain : Mycoplasma pulmonis UAB CTIP
Genome accession: NC_002771
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 663546 - 664571 bp
Length : 1026 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGAGTCAAAAAGAAAGAAAGACTTATTTTGAAGATTCAACTTCTCCATTAGAATTTGCTCTTAATAATTTTAGAGGAAA
AATGCGCTCTGTTAATTGAAATAAAATTGATGATGAAAAAGATTTAGAAGTGTGAAATAGAGTTTGTCAAAATTTTTGAC
TTCCTGAAAAAATTCCTGTTTCAAATGATTTAGAAACTTGAAGATCTCTTGATCCTATTTGACAAAAAGTAATTACCAGA
ACCTTTACTGGCTTAACTCTTTTAGATACCATCCAAGCTACCATCGGTGACATAGCACAACTTCCTCATTCTTTAACTGA
TCATGAGCAAGTTATTTATACGAACTTTGCTTTTATGGTGGCAATTCATGCTCGCTCTTATGGAACAATTTTTTCAACAC
TTTGTTCAACTGAGCAAATTAATGAAGCTCATGAATGAGTAATTAATACCAAAAGCTTGCAAGATAGAGCAAAAATTTTA
ATTCCTTTTTATACTGGAAAAGATCCTTTAAAATCAAAAGTAGCAGCTGCTTTAATGCCTGGATTTTTGCTTTATGGTGG
TTTTTATTTACCTTTTTATCTTTCTTCAAGAATGAAGCTTCCTAATACTTCAGATATTATTAGACTAATTCTTAGAGATA
AGGTAATTCACAACTATTATTCAGGATATAAATATCAAAAGAAAGTTGAAAAACTTTCTCTTGAAAAACAAAAAGAAATG
AAAGAATTTGTTTTTGATCTTTTATATAAGTTAATTGATTTAGAAAAAAAATATTTATATGAGCTCTATGAAGAAATTGG
ACTTGCAGAAGATGCTATTAAATTTTCTTTATACAATGCAGGTAAATTTTTGCAAAATTTAGGTTATGACTCACCTTTTA
CTAGTGAAGAGACTAAAATTGATGCTGAAATTTTTAGTCAACTCTCAGCTAGAGCAGATGAAAACCATGATTTTTTTTCT
GGAAATGGCTCTTCATATGTAATGGGTATTAGTGAAGAAACAGAAGATGAAGATTGAGAATTTTAA

Protein sequence :
MSQKERKTYFEDSTSPLEFALNNFRGKMRSVNWNKIDDEKDLEVWNRVCQNFWLPEKIPVSNDLETWRSLDPIWQKVITR
TFTGLTLLDTIQATIGDIAQLPHSLTDHEQVIYTNFAFMVAIHARSYGTIFSTLCSTEQINEAHEWVINTKSLQDRAKIL
IPFYTGKDPLKSKVAAALMPGFLLYGGFYLPFYLSSRMKLPNTSDIIRLILRDKVIHNYYSGYKYQKKVEKLSLEKQKEM
KEFVFDLLYKLIDLEKKYLYELYEEIGLAEDAIKFSLYNAGKFLQNLGYDSPFTSEETKIDAEIFSQLSARADENHDFFS
GNGSSYVMGISEETEDEDWEF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 2e-65 52