Gene Information

Name : set11 (SAV0426)
Accession : NP_370950.1
Strain : Staphylococcus aureus Mu50
Genome accession: NC_002758
Putative virulence/resistance : Virulence
Product : superantigen-like protein 7
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 471396 - 472091 bp
Length : 696 bp
Strand : +
Note : SSL7, SET1; blocks IgA-FcR interactions and inhibits complement, leading to increased survival of a sensitive bacterium in blood

DNA sequence : 
ATGAAATTAAAAACGTTAGCTAAAGCAACATTGGCATTAGGCTTATTAACTACTGGTGTGATTACATCAGAAGGCCAAGC
AGTCCACGCAAAAGAAAAGCAAGAGAGAGTACAACATTTATATGATATTAAAGACTTATATCGATACTACTCATCAGAAA
GTTTTGAATTCAGTAATATTAGTGGTAAGGTTGAAAACTATAACGGTTCTAACGTTGTACGCTTTAACCAAGAAAAACAA
AATCACCAATTATTCTTATTAGGAAAAGATAAAGATAAATATAAAAAAGGCCTTGAAGGCCAGAATGTCTTTGTGGTAAA
AGAATTAATTGATCCAAACGGTAGACTATCTACTGTTGGTGGTGTGACTAAGAAAAATAACAAATCTTCTGAAACTAATA
CACATTTATTTGTTAATAAAGTGTATGGCGGAAATTTAGATGCATCAATTGACTCATTTTTAATTAATAAAGAAGAAGTT
TCACTGAAAGAACTTGATTTCAAAATTAGAAAGCAATTAGTTGAAAAATATGGTTTATATAAAGGTACGACTAAATACGG
TAAGATCACTATCAATTTGAAAGACGAGAAAAAGGAAGTAATTGATTTAGGTGATAAACTGCAATTCGAGCGCATGGGTG
ATGTGTTGAATAGTAAGGATATTCAAAATATAGCAGTGACTATTAATCAAATTTAA

Protein sequence : 
MKLKTLAKATLALGLLTTGVITSEGQAVHAKEKQERVQHLYDIKDLYRYYSSESFEFSNISGKVENYNGSNVVRFNQEKQ
NHQLFLLGKDKDKYKKGLEGQNVFVVKELIDPNGRLSTVGGVTKKNNKSSETNTHLFVNKVYGGNLDASIDSFLINKEEV
SLKELDFKIRKQLVEKYGLYKGTTKYGKITINLKDEKKEVIDLGDKLQFERMGDVLNSKDIQNIAVTINQI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
set11 NP_370950.1 superantigen-like protein 7 Virulence vSa¥á Protein 1e-76 100
set11 NP_373637.1 superantigen-like protein 7 Virulence vSa¥á Protein 1e-76 100
SAS0390 YP_042515.1 superantigen-like protein 7 Virulence vSa¥á Protein 1e-68 91
set22 NP_645205.1 superantigen-like protein 7 Virulence vSa¥á Protein 1e-68 91
set7nm YP_001331428.1 superantigen-like protein 7 Virulence vSa¥á Protein 3e-68 90
SAUSA300_0401 YP_493115.1 superantigen-like protein 7 Virulence vSa¥á Protein 3e-68 90
SAKOR_00410 YP_008490594.1 Exotoxin Virulence vSa¥á Protein 3e-66 88
SAMSHR1132_03760 YP_005324898.1 exotoxin 1 Virulence vSa¥á Protein 7e-67 86
set1 YP_039880.1 superantigen-like protein 7 Virulence vSa¥á Protein 9e-64 85
set13 NP_370952.1 superantigen-like protein Virulence vSa¥á Protein 1e-30 56
set13 NP_373639.1 superantigen-like protein Virulence vSa¥á Protein 1e-30 56
set9nm YP_001331430.1 superantigen-like protein Virulence vSa¥á Protein 1e-29 55
SAUSA300_0403 YP_493117.1 superantigen-like protein Virulence vSa¥á Protein 1e-29 55
SAS0392 YP_042517.1 superantigen-like protein Virulence vSa¥á Protein 3e-30 55
set24 NP_645207.1 superantigen-like protein Virulence vSa¥á Protein 3e-30 55
SACOL0473 YP_185363.1 superantigen-like protein Virulence vSa¥á Protein 1e-29 55
SAKOR_00412 YP_008490596.1 Exotoxin Virulence vSa¥á Protein 4e-30 55
set5 YP_039881.1 superantigen-like protein Virulence vSa¥á Protein 4e-30 54
set8nm YP_001331429.2 superantigen-like protein Virulence vSa¥á Protein 8e-32 53
SAUSA300_0402 YP_493116.1 superantigen-like protein Virulence vSa¥á Protein 8e-32 53
set12 NP_370951.1 superantigen-like protein Virulence vSa¥á Protein 7e-32 53
set12 NP_373638.1 superantigen-like protein Virulence vSa¥á Protein 7e-32 53
SAKOR_00411 YP_008490595.1 Exotoxin Virulence vSa¥á Protein 2e-31 53
SAS0391 YP_042516.2 superantigen-like protein Virulence vSa¥á Protein 4e-31 52
set23 NP_645206.1 superantigen-like protein Virulence vSa¥á Protein 4e-31 52