Gene Information

Name : SAV2443 (SAV2443)
Accession : NP_372967.1
Strain : Staphylococcus aureus Mu50
Genome accession: NC_002758
Putative virulence/resistance : Unknown
Product : 2-dehydropantoate 2-reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1893
EC number : 1.1.1.169
Position : 2577820 - 2578755 bp
Length : 936 bp
Strand : -
Note : ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis

DNA sequence :
ATGAAAATTGCAATTGCTGGATCGGGTGCATTAGGTAGTGGCTTTGGTGCCAAACTATTTCAAGCAGGATATGATGTCAC
ACTTATTGACGGATATACATCTCATGTTGAAGCGGTTAAGCAACATGGATTAAATATAACGATTAATGGAGAGGCATTCG
AGTTAAACATTCCGATGTATCATTTTAATGATCAACGGGACGAAAGCATTTACGATGTTGTCTTTCTATTTCCAAAGTCT
ATGCAATTAAAAGAAGTGATGGAAGATATGAAGCCACATATTGATAATGAAACGATCGTCGTATGTACGATGAATGGTCT
GAAGCATGAAGAAGTCATTGCGCAGTATGTTGCTCAATCACAAATTGTCAGAGGTGTTACGACTTGGACGGCAGGTCTTG
AAAGCCCTGGACACAGTCATTTACTTGGTAGTGGACCAGTTGAAATAGGTGAACTAGTGGATGAAGGTAAAGAAAATGTT
ATAAAAGTTGCTGATTTACTTAACGAAGCGGAATTGAATGGTGTCATTAGTAAAGATTTATACCAATCGATTTGGAAAAA
GATTTGTGTTAATGGTACGGCAAATGCATTAAGCACAGTGTTGGAGTGTAATATGGCATCACTGAATGAAAGTAGTTATG
CGAAGTGTTTGATTTATAAATTAACGCAAGAAATAGTGCATGTAGCGACGATTGATAATGTTCATTTAAATGTTGATGAA
GCATTTGAATATTTAGTTGATTTAAATGAAAAAGTTGGTGCGCATTATCCATCCATGTATCAAGATTTAATTGTTAATAA
TAGAAAAACTGAAATTGATTATATTAATGGCGCAGTTGCAACATTGGGTAAACAACGTCATATTGAAGCGCCAGTCAATC
GCTTTATTACTGATTTAATTCATACTAAAGAAAGTCAGCGACACGCACAGGATTAA

Protein sequence :
MKIAIAGSGALGSGFGAKLFQAGYDVTLIDGYTSHVEAVKQHGLNITINGEAFELNIPMYHFNDQRDESIYDVVFLFPKS
MQLKEVMEDMKPHIDNETIVVCTMNGLKHEEVIAQYVAQSQIVRGVTTWTAGLESPGHSHLLGSGPVEIGELVDEGKENV
IKVADLLNEAELNGVISKDLYQSIWKKICVNGTANALSTVLECNMASLNESSYAKCLIYKLTQEIVHVATIDNVHLNVDE
AFEYLVDLNEKVGAHYPSMYQDLIVNNRKTEIDYINGAVATLGKQRHIEAPVNRFITDLIHTKESQRHAQD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF0517 NP_814296.1 2-dehydropantoate 2-reductase Not tested Not named Protein 9e-48 42
ef0037 AAM75243.1 EF0037 Not tested Not named Protein 6e-48 42