Gene Information

Name : SAV2006 (SAV2006)
Accession : NP_372530.1
Strain : Staphylococcus aureus Mu50
Genome accession: NC_002758
Putative virulence/resistance : Unknown
Product : succinyl-diaminopimelate desuccinylase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0624
EC number : -
Position : 2129758 - 2130960 bp
Length : 1203 bp
Strand : +
Note : dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is simi

DNA sequence :
ATGACAACTTTTAGTGAAAAAGAAAAAATTCAATTACTAGCAGATATTGTTGAACTACAAACTGAAAATAATAATGAAAT
AGACGTTTGTAATTATTTAAAAGATTTATTCGACAAGTACGATATTAAATCTGAAATTTTGAAAGTTAATGAACACCGCG
CCAATATCGTTGCAGAAATCGGTAACGGCTCACCTATACTCGCATTGAGTGGTCATATGGATGTTGTTGATGCAGGAAAT
CAAGATAATTGGACTTATCCCCCTTTTCAACTCACAGAAAAAGCTGGCAAATTATACGGTCGAGGCACAACGGATATGAA
AGGCGGTCTGATGGCTTTGGTCATCACACTCATTGAATTAAAAGAACAAAATCAATTGCCTCAAGGAACGATAAGATTAC
TAGCTACTGCTGGCGAAGAGAAAGAACAAGAAGGTGCCAAATTATTGGCTGATAAAGGCTATTTAGACGATGTAGATGGC
TTAATTATTGCTGAACCAACTGGATCTGGAATTTATTATGCACATAAAGGGTCTATGTCATGTAAAGTAACTGCAACTGG
CAAAGCTGTCCATAGCTCAGTTCCATTTATTGGTGACAATGCAATTGATACACTGCTTGAATTTTATAATCAATTTAAAG
AAAAATATTCAGAGCTTAAAAAACATGATACTAAACATGAATTAGATGTTGCACCCATGTTCAAATCATTGATAGGAAAA
GAAATTTCTGAAGAGGATGCAAATTATGCATCTGGTCTTACAGCTGTATGTTCGATTATAAATGGCGGCAAACAATTTAA
CTCTGTACCAGATGAAGCTTCACTTGAATTTAACGTAAGACCAGTTCCTGAGTATGATAACGACTTTATAGAATCGTTTT
TCCAAAATATCATTAATGATGTGGATAGCAATAAGCTTTCACTCGATATTCCAAGCAATCACCGACCTGTAACAAGCGAT
AAAAATAGCAAATTAATTACTACGATTAAAGATGTAGCTTCTAGTTATGTAGAACAAGACGAAATATTTGTTTCAGCGCT
TGTAGGTGCAACAGATGCCTCTAGTTTCTTAGGAGATAATAAGGACAATGTTGATTTAGCCATTTTTGGACCAGGTAATC
CATTAATGGCACATCAAATCGATGAATATTGTTTGACTGTAAATATTCAAATATCAACAAGCACATTTTCATTGATTAAG
TGA

Protein sequence :
MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILALSGHMDVVDAGN
QDNWTYPPFQLTEKAGKLYGRGTTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDG
LIIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGK
EISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINDVDSNKLSLDIPSNHRPVTSD
KNSKLITTIKDVASSYVEQDEIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYCLTVNIQISTSTFSLIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dapE CAA07459.1 succinyl-diaminopimelate desuccinylase Not tested Internalin Protein 2e-61 45
unnamed CAC20637.1 - Not tested Internalin Protein 5e-61 44