Gene Information

Name : deoA (MT3415)
Accession : NP_337943.1
Strain : Mycobacterium tuberculosis CDC1551
Genome accession: NC_002755
Putative virulence/resistance : Unknown
Product : thymidine phosphorylase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0213
EC number : 2.4.2.4
Position : 3697072 - 3698355 bp
Length : 1284 bp
Strand : -
Note : Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate

DNA sequence :
GTGACCGACTTCGCATTCGACGCCCCGACCGTCATCCGCACCAAACGTGACGGCGGCCGGTTGTCCGACGCCGCCATCGA
CTGGGTCGTCAAGGCCTATACCGACGGCCGGGTCGCCGACGAACAGATGTCGGCGCTGCTGATGGCGATCGTTTGGCGGG
GCATGGACCGCGGCGAGATCGCCAGATGGACGGCGGCCATGCTGGCCTCGGGTGCCCGGCTGGATTTCACCGATCTGCCA
CTAGCGACCGTGGACAAGCATTCCACCGGCGGGGTAGGTGACAAAATCACGCTGCCATTGGTGCCCGTCGTCGCCGCCTG
CGGTGGCGCAGTGCCCCAGGCGTCGGGCCGCGGACTCGGCCACACCGGCGGCACCCTGGACAAGCTGGAATCCATCACCG
GGTTCACCGCGAATCTGTCCAACCAGCGGGTGCGCGAGCAGCTTTGCGACGTCGGCGCCGCGATCTTCGCCGCCGGCCAG
CTGGCGCCAGCCGATGCCAAGCTGTATGCGCTGCGCGACATTACCGGCACCGTCGAATCGCTGCCGTTGATCGCCAGTTC
GATTATGAGCAAGAAGCTGGCTGAGGGTGCGGGTGCACTGGTGCTCGACGTCAAGGTTGGTTCCGGGGCCTTCATGAGGT
CGCCAGTGCAGGCGCGCGAACTTGCGCACACCATGGTCGAACTGGGCGCGGCGCATGGCGTGCCCACCCGTGCCCTGCTG
ACGGAGATGAACTGCCCGCTGGGTCGAACCGTCGGCAATGCGCTCGAGGTGGCCGAGGCGCTGGAGGTGCTGGCCGGCGG
CGGACCGCCCGACGTGGTGGAGCTGACGTTGCGGCTGGCCGGCGAGATGCTCGAGCTTGCCGGGATCCACGGCCGGGACC
CGGCCCAGACGCTGCGGGACGGCACCGCAATGGACCGGTTTCGCCGGTTGGTTGCCGCGCAGGGAGGTGACTTGTCGAAA
CCGTTGCCGATCGGTTCGCATTCGGAAACCGTCACGGCGGGCGCGAGCGGCACAATGGGCGACATCGATGCGATGGCAGT
GGGGTTAGCGGCATGGCGACTCGGTGCGGGCAGGTCCCGCCCGGGCGCACGCGTACAGCACGGTGCGGGGGTGCGGATTC
ATCGCCGCCCGGGGGAGCCGGTTGTGGTCGGTGAGCCGTTGTTCACCCTCTACACGAATGCTCCCGAGCGCTTTGGTGCG
GCGCGAGCCGAGCTGGCCGGCGGTTGGAGTATCCGGGACAGTCCGCCGCAGGTGCGGCCGCTAATCGTCGATCGGATCGT
CTGA

Protein sequence :
MTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTAAMLASGARLDFTDLP
LATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ
LAPADAKLYALRDITGTVESLPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL
TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAMDRFRRLVAAQGGDLSK
PLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGA
ARAELAGGWSIRDSPPQVRPLIVDRIV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
deoA YP_005163381.1 Thymidine phosphorylase Not tested Not named Protein 7e-95 57