Gene Information

Name : glnA-1 (MT2278)
Accession : NP_336749.1
Strain : Mycobacterium tuberculosis CDC1551
Genome accession: NC_002755
Putative virulence/resistance : Virulence
Product : glutamine synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0174
EC number : 6.3.1.2
Position : 2484890 - 2486326 bp
Length : 1437 bp
Strand : +
Note : identified by similarity to EGAD:14858; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653

DNA sequence :
GTGACGGAAAAGACGCCCGACGACGTCTTCAAACTTGCCAAGGACGAGAAGGTCGAATATGTCGACGTCCGGTTCTGTGA
CCTGCCTGGCATCATGCAGCACTTCACGATTCCGGCTTCGGCCTTTGACAAGAGCGTGTTTGACGACGGCTTGGCCTTTG
ACGGCTCGTCGATTCGCGGGTTCCAGTCGATCCACGAATCCGACATGTTGCTTCTTCCCGATCCCGAGACGGCGCGCATC
GACCCGTTCCGCGCGGCCAAGACGCTGAATATCAACTTCTTTGTGCACGACCCGTTCACCCTGGAGCCGTACTCCCGCGA
CCCGCGCAACATCGCCCGCAAGGCCGAGAACTACCTGATCAGCACTGGCATCGCCGACACCGCATACTTCGGCGCCGAGG
CCGAGTTCTACATTTTCGATTCGGTGAGCTTCGACTCGCGCGCCAACGGCTCCTTCTACGAGGTGGACGCCATCTCGGGG
TGGTGGAACACCGGCGCGGCGACCGAGGCCGACGGCAGTCCCAACCGGGGCTACAAGGTCCGCCACAAGGGCGGGTATTT
CCCAGTGGCCCCCAACGACCAATACGTCGACCTGCGCGACAAGATGCTGACCAACCTGATCAACTCCGGCTTCATCCTGG
AGAAGGGCCACCACGAGGTGGGCAGCGGCGGACAGGCCGAGATCAACTACCAGTTCAATTCGCTGCTGCACGCCGCCGAC
GACATGCAGTTGTACAAGTACATCATCAAGAACACCGCCTGGCAGAACGGCAAAACGGTCACGTTCATGCCCAAGCCGCT
GTTCGGCGACAACGGGTCCGGCATGCACTGTCATCAGTCGCTGTGGAAGGACGGGGCCCCGCTGATGTACGACGAGACGG
GTTATGCCGGTCTGTCGGACACGGCCCGTCATTACATCGGCGGCCTGTTACACCACGCGCCGTCGCTGCTGGCCTTCACC
AACCCGACGGTGAACTCCTACAAGCGGCTGGTTCCCGGTTACGAGGCCCCGATCAACCTGGTCTATAGCCAGCGCAACCG
GTCGGCATGCGTGCGCATCCCGATCACCGGCAGCAACCCGAAGGCCAAGCGGCTGGAGTTCCGAAGCCCCGACTCGTCGG
GCAACCCGTATCTGGCGTTCTCGGCCATGCTGATGGCAGGCCTGGACGGTATCAAGAACAAGATCGAGCCGCAGGCGCCC
GTCGACAAGGATCTCTACGAGCTGCCGCCGGAAGAGGCCGCGAGTATCCCGCAGACTCCGACCCAGCTGTCAGATGTGAT
CGACCGTCTCGAGGCCGACCACGAATACCTCACCGAAGGAGGGGTGTTCACAAACGACCTGATCGAGACGTGGATCAGTT
TCAAGCGCGAAAACGAGATCGAGCCGGTCAACATCCGGCCGCATCCCTACGAATTCGCGCTGTACTACGACGTTTAA

Protein sequence :
MTEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARI
DPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISG
WWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAAD
DMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFT
NPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAP
VDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 8e-89 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA-1 NP_336749.1 glutamine synthetase VFG1399 Protein 0.0 100