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Name : nrdF1 (MT2033) Accession : NP_336494.1 Strain : Mycobacterium tuberculosis CDC1551 Genome accession: NC_002755 Putative virulence/resistance : Unknown Product : ribonucleotide-diphosphate reductase subunit beta Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0208 EC number : 1.17.4.1 Position : 2221553 - 2222521 bp Length : 969 bp Strand : - Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE DNA sequence : ATGACCGGCAAGCTCGTTGAGCGGGTGCACGCAATCAATTGGAACCGGTTGCTCGATGCTAAAGATTTGCAGGTCTGGGA ACGTTTGACCGGTAACTTTTGGTTGCCGGAAAAGATTCCGCTCTCCAACGACCTGGCATCTTGGCAAACGTTGAGTTCCA CCGAGCAGCAGACGACGATCCGGGTGTTCACCGGCTTGACCCTGCTCGACACCGCGCAGGCGACGGTGGGAGCAGTGGCC ATGATCGACGACGCGGTCACCCCCCACGAAGAGGCGGTCCTGACCAACATGGCGTTCATGGAGTCAGTGCACGCCAAGAG CTACAGCTCGATCTTCTCGACCCTGTGCTCGACCAAGCAGATCGACGATGCCTTCGACTGGTCGGAACAGAACCCTTACC TGCAGCGAAAAGCGCAGATCATCGTCGACTACTACCGCGGTGACGACGCGCTCAAGCGCAAAGCATCGTCGGTAATGCTG GAGTCCTTCCTGTTCTACTCCGGCTTCTACCTGCCCATGTACTGGTCGTCGCGGGGTAAGCTCACCAACACCGCCGATCT GATCCGGCTGATCATCCGAGATGAAGCCGTCCACGGCTACTACATCGGCTACAAATGTCAACGAGGTTTGGCCGACCTGA CCGACGCCGAGCGGGCCGACCACCGCGAATACACCTGCGAGCTGCTGCACACGCTCTACGCGAACGAGATCGACTATGCG CACGACTTGTACGACGAGTTGGGCTGGACCGACGACGTTTTGCCCTACATGCGTTACAACGCCAACAAGGCGCTAGCCAA CCTGGGATACCAGCCTGCATTCGATCGTGACACCTGCCAGGTGAACCCGGCCGTGCGCGCAGCTCTCGACCCCGGTGCAG GGGAGAACCACGACTTTTTCTCCGGCTCCGGAAGCTCATACGTAATGGGCACCCACCAACCCACCACCGACACCGACTGG GACTTCTAA Protein sequence : MTGKLVERVHAINWNRLLDAKDLQVWERLTGNFWLPEKIPLSNDLASWQTLSSTEQQTTIRVFTGLTLLDTAQATVGAVA MIDDAVTPHEEAVLTNMAFMESVHAKSYSSIFSTLCSTKQIDDAFDWSEQNPYLQRKAQIIVDYYRGDDALKRKASSVML ESFLFYSGFYLPMYWSSRGKLTNTADLIRLIIRDEAVHGYYIGYKCQRGLADLTDAERADHREYTCELLHTLYANEIDYA HDLYDELGWTDDVLPYMRYNANKALANLGYQPAFDRDTCQVNPAVRAALDPGAGENHDFFSGSGSSYVMGTHQPTTDTDW DF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| cur_1479 | YP_001800873.1 | ribonucleoside-diphosphate reductase subunit beta | Not tested | Not named | Protein | 5e-102 | 63 |
