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Name : tkt (MT1496) Accession : NP_335945.1 Strain : Mycobacterium tuberculosis CDC1551 Genome accession: NC_002755 Putative virulence/resistance : Unknown Product : transketolase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : 2.2.1.1 Position : 1627979 - 1630156 bp Length : 2178 bp Strand : - Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo DNA sequence : ATGCGGCACTGCAAGCGCCGGGATTCCCGCACTAGGGTGAGGACTGATCATCTTGCTGACTCGAGGACTGAATTTGTGAC CACACTCGAAGAGATCTCCGCGCTTACCCGACCGCGCCATCCCGACGACTGGACCGAGATCGATTCGGCTGCCGTCGACA CCATCCGGGTATTGGCCGCCGATGCCGTCCAAAAGGTCGGCAACGGTCATCCTGGAACGGCGATGAGCCTGGCTCCGTTG GCCTACACGCTGTTTCAGCGGACAATGCGTCACGATCCCAGCGACACACACTGGCTGGGCCGCGATCGGTTCGTTTTGTC GGCCGGGCACAGCAGCCTGACCCTCTACATCCAGCTCTACCTCGGCGGCTTCGGCCTGGAACTGTCCGACATTGAGTCGT TGCGCACCTGGGGATCCAAGACCCCCGGACACCCGGAGTTCCGCCACACCCCCGGCGTTGAGATCACCACCGGCCCGCTG GGGCAGGGACTGGCGTCGGCGGTCGGGATGGCGATGGCCTCGCGCTACGAGCGCGGCCTGTTCGACCCGGACGCCGAACC GGGCGCCAGCCCCTTCGACCACTACATCTATGTCATCGCCTCCGACGGTGACATCGAAGAAGGGGTGACCTCGGAGGCGT CGTCGCTGGCCGCGGTCCAGCAACTGGGCAACCTCATCGTGTTCTACGACCGCAACCAGATCTCGATCGAGGACGACACC AACATCGCGCTGTGTGAGGACACCGCGGCCCGCTACCGCGCGTACGGCTGGCACGTGCAAGAGGTTGAGGGCGGTGAGAA CGTCGTCGGCATCGAGGAGGCCATCGCCAATGCGCAGGCGGTCACCGACCGGCCCTCGTTCATCGCGCTGCGCACCGTCA TCGGCTATCCGGCGCCGAACCTGATGGACACCGGCAAGGCGCACGGCGCGGCGCTGGGCGACGACGAGGTGGCCGCAGTC AAGAAGATCGTCGGCTTCGATCCGGACAAGACGTTCCAGGTCCGCGAGGACGTCCTCACCCACACCCGAGGGCTGGTGGC CCGCGGCAAACAGGCCCACGAACGCTGGCAGCTCGAATTCGATGCCTGGGCGCGGCGTGAACCCGAGCGCAAGGCGCTGC TGGACCGGCTGCTCGCGCAGAAGTTGCCCGACGGCTGGGACGCCGACTTGCCCCACTGGGAACCGGGGTCCAAGGCGCTG GCCACCCGTGCGGCCTCGGGTGCGGTGCTGTCCGCGCTCGGGCCGAAACTGCCCGAGTTGTGGGGCGGTTCGGCCGACCT GGCGGGCAGCAACAACACAACGATAAAGGGCGCCGACTCCTTTGGCCCGCCCTCGATTTCCACCAAGGAGTACACCGCGC ACTGGTATGGTCGCACCTTGCACTTCGGTGTTCGCGAGCACGCGATGGGTGCCATCCTGTCCGGCATCGTGCTGCACGGA CCCACCCGGGCTTACGGCGGCACCTTCCTGCAGTTCTCCGACTACATGCGCCCGGCGGTGCGGCTGGCGGCGTTGATGGA CATCGACACCATCTACGTCTGGACGCACGACTCGATCGGCCTCGGCGAAGACGGGCCCACCCATCAACCGATCGAGCACC TCTCGGCGCTGCGCGCGATCCCCCGGCTGTCGGTGGTGCGCCCGGCAGATGCCAACGAGACAGCCTACGCCTGGCGCACG ATCCTGGCCCGCCGCAACGGCAGCGGGCCGGTCGGGTTGATCCTGACCCGCCAGGGTGTGCCGGTGCTGGACGGCACCGA CGCCGAGGGGGTTGCCCGCGGCGGTTACGTGCTGAGTGACGCCGGTGGTCTGCAACCGGGCGAGGAACCCGACGTCATTC TCATCGCCACCGGCTCGGAGGTGCAGCTGGCGGTCGCGGCGCAGACGTTGCTGGCGGACAACGACATCCTCGCTCGGGTG GTGTCGATGCCGTGCCTGGAGTGGTTCGAGGCCCAACCCTACGAGTACCGCGACGCGGTGCTGCCCCCGACGGTGTCGGC GCGGGTGGCCGTCGAAGCCGGCGTCGCGCAATGCTGGCACCAGCTGGTTGGCGACACGGGCGAGATCGTCTCGATCGAGC ACTACGGCGAATCCGCGGACCACAAGACCTTGTTCCGCGAGTACGGCTTCACTGCCGAGGCCGTGGCCGCCGCCGCCGAA CGAGCGCTGGATAACTGA Protein sequence : MRHCKRRDSRTRVRTDHLADSRTEFVTTLEEISALTRPRHPDDWTEIDSAAVDTIRVLAADAVQKVGNGHPGTAMSLAPL AYTLFQRTMRHDPSDTHWLGRDRFVLSAGHSSLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTPGVEITTGPL GQGLASAVGMAMASRYERGLFDPDAEPGASPFDHYIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDRNQISIEDDT NIALCEDTAARYRAYGWHVQEVEGGENVVGIEEAIANAQAVTDRPSFIALRTVIGYPAPNLMDTGKAHGAALGDDEVAAV KKIVGFDPDKTFQVREDVLTHTRGLVARGKQAHERWQLEFDAWARREPERKALLDRLLAQKLPDGWDADLPHWEPGSKAL ATRAASGAVLSALGPKLPELWGGSADLAGSNNTTIKGADSFGPPSISTKEYTAHWYGRTLHFGVREHAMGAILSGIVLHG PTRAYGGTFLQFSDYMRPAVRLAALMDIDTIYVWTHDSIGLGEDGPTHQPIEHLSALRAIPRLSVVRPADANETAYAWRT ILARRNGSGPVGLILTRQGVPVLDGTDAEGVARGGYVLSDAGGLQPGEEPDVILIATGSEVQLAVAAQTLLADNDILARV VSMPCLEWFEAQPYEYRDAVLPPTVSARVAVEAGVAQCWHQLVGDTGEIVSIEHYGESADHKTLFREYGFTAEAVAAAAE RALDN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 3e-113 | 44 |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 1e-112 | 42 |
