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Name : metB (MT1110) Accession : NP_335552.1 Strain : Mycobacterium tuberculosis CDC1551 Genome accession: NC_002755 Putative virulence/resistance : Resistance Product : cystathionine gamma-synthase Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0626 EC number : 2.5.1.48 Position : 1204302 - 1205468 bp Length : 1167 bp Strand : + Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine DNA sequence : ATGAGCGAAGACCGCACGGGACACCAGGGAATCAGCGGACCGGCCACCCGCGCCATCCACGCTGGCTACCGCCCGGATCC GGCGACCGGGGCGGTGAACGTGCCGATCTACGCCAGCAGCACCTTCGCCCAAGACGGCGTCGGCGGTCTGCGTGGCGGTT TCGAATACGCACGCACCGGCAACCCCACCCGGGCCGCATTGGAGGCCTCGCTGGCGGCAGTCGAGGAGGGTGCTTTCGCG CGGGCATTCAGTTCCGGGATGGCCGCGACCGACTGCGCCCTGCGGGCGATGTTACGGCCCGGAGACCACGTCGTCATTCC CGATGACGCCTACGGCGGCACATTCCGGTTGATAGACAAGGTGTTCACCCGGTGGGATGTCCAGTACACGCCGGTGCGGC TTGCCGATCTGGATGCGGTGGGTGCCGCGATTACTCCGCGCACCCGGCTGATTTGGGTGGAGACGCCCACCAATCCGCTA CTGTCGATCGCCGATATCACGGCCATTGCCGAGCTGGGCACAGACAGATCGGCAAAAGTATTGGTGGACAATACCTTTGC CTCACCCGCGTTGCAGCAGCCGTTGCGGCTGGGCGCCGATGTGGTGTTGCACTCGACTACCAAGTACATCGGCGGCCATT CCGACGTGGTGGGAGGTGCGCTGGTCACCAACGACGAAGAGCTGGACGAGGAGTTCGCTTTCTTGCAGAACGGCGCCGGC GCGGTGCCCGGACCATTCGACGCCTACCTGACCATGCGCGGCCTGAAGACCTTGGTGCTGCGGATGCAGCGGCACAGTGA AAATGCCTGTGCGGTAGCGGAATTCCTCGCTGATCATCCGTCGGTGAGTTCTGTGTTGTATCCGGGTTTGCCCAGTCATC CCGGGCATGAGATTGCCGCGCGACAGATGCGCGGCTTCGGCGGCATGGTTTCGGTGCGGATGCGGGCCGGTCGGCGTGCG GCGCAGGACCTGTGTGCCAAGACCCGCGTCTTCATCCTGGCCGAGTCGCTGGGTGGGGTGGAGTCGCTGATCGAACATCC CAGCGCCATGACCCATGCGTCGACGGCCGGTTCGCAATTGGAGGTGCCCGACGATCTGGTGCGGCTTTCGGTCGGTATCG AAGACATTGCCGACCTGCTCGGCGATCTCGAACAGGCCCTGGGTTAA Protein sequence : MSEDRTGHQGISGPATRAIHAGYRPDPATGAVNVPIYASSTFAQDGVGGLRGGFEYARTGNPTRAALEASLAAVEEGAFA RAFSSGMAATDCALRAMLRPGDHVVIPDDAYGGTFRLIDKVFTRWDVQYTPVRLADLDAVGAAITPRTRLIWVETPTNPL LSIADITAIAELGTDRSAKVLVDNTFASPALQQPLRLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDEEFAFLQNGAG AVPGPFDAYLTMRGLKTLVLRMQRHSENACAVAEFLADHPSVSSVLYPGLPSHPGHEIAARQMRGFGGMVSVRMRAGRRA AQDLCAKTRVFILAESLGGVESLIEHPSAMTHASTAGSQLEVPDDLVRLSVGIEDIADLLGDLEQALG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAR0460 | YP_039909.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 2e-71 | 45 |
| SAS0418 | YP_042545.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 2e-72 | 45 |
| metB | YP_281510.1 | cystathionine beta-lyase | Not tested | Not named | Protein | 7e-56 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| metB | NP_335552.1 | cystathionine gamma-synthase | BAC0207 | Protein | 1e-60 | 43 |
