Gene Information

Name : merA (SSO2689)
Accession : NP_344015.1
Strain : Sulfolobus solfataricus P2
Genome accession: NC_002754
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.16.1.1
Position : 2445401 - 2446762 bp
Length : 1362 bp
Strand : +
Note : Cellular Processes, Detoxification

DNA sequence :
GTGGAAGATCTGGTGATCATAGGATACGGCGCAGCTGGATTTGCGGCGTTAATTAGGGCAAATGAACTCGGAATAAAGCC
AGTGGTTGTAGGTTATGGAGAAATAGGCGGAACTTGCGTTAATGTAGGATGTGTTCCATCGAAGAGAATGTTGAGAATAG
GTGAATTGTACAATTACTCTTCAAAAGTAATAGGAAAAAAGTTGTTTCCAGAATTTTTCCAAGCCTTTCAAGACAAGGCT
GAAATCGTAAATTCCCTGCGAAAGGAAAAATACGAGGATGTGATAAATTCATATGATATCAAATTAAAAATTGGTAAAGC
ATATTTTACTTCACCTAATGCAGTTAAAGTAAATGGTGAGATAATAGAGGCTAAAAAGTTTATAATAGCCACAGGCTCTT
CTCCCAATATACCTAACATAAAGGGTTTAACTGAAGTTGGATTTTGGACTAATGTGGAAGCCTTATCACCAGACAAGACA
ATATCATCCTTGGCTATTATAGGCGGAAGGGCATTGGCGTTAGAGTTCGCACAAATGTATAAGAGACTAGGAGTTGATAC
TACAATTCTTCAAAGGAGCGGAAGAATATTACCGGATTGGGAGCCTGAAATTTCCCTTTCCGTTAAAAACTATTTAGAGG
AGAATGATAGTATTCCAATTTTTACAAATGTGAGAGTTAAGGAGGTTAGAAAAGGAAACGGGGGAAAGATAATAGTTACT
GATAAGGGTGAAGTTGAGGCTGATGAAATTCTGTTAGCTACCGGAAGAAAGCCCAATGTAGATTTAAATTTAGATGCAGC
AGGAATCGAATTAAACGATAAGGGAGGCATAAAAGTTAATGAAGAACTAAGAACCTCAAATCCTAATGTATTTGCCGCAG
GAGATGTAATTGGCGGTCCTATGTTGGAAGCTCTAGCTGGCAGACAAGGTTCAATTGCGGCAGAGAACGCAATAATGAAT
GTGCATAGAAAGATTGATATGTTAAGTGTACCTCAAGTTGTGTTTATAGAGCCGAATGTAGCTAAAGTTGGTCTCACTGC
ACTTGAAGCAGTAAAAGAAGGCTATGATATAGACCAAAGGGTAGTAAAAATGGATAATATAGCTAAAGCGAGGATATTAA
GGGAAAATTACGGATTAATAAAAATGGTTATAGATAAGAAGTTTAGGAACATTTTAGGTGTCCAGATGTTTGGTAAATAC
GCAGCTGAAGTGATAAATGAGGCAGCATTAGCACTTAGATTTAGGGCTACAATAGATGACTTGATCGATACAATACATGT
CTTTCCCACAATGGGAGAAAGTTTAAGAATAGCAGCGTTAGCTTTTACCGGTGACGTTAGTAAAATGAGTTGTTGTGTAT
AG

Protein sequence :
MEDLVIIGYGAAGFAALIRANELGIKPVVVGYGEIGGTCVNVGCVPSKRMLRIGELYNYSSKVIGKKLFPEFFQAFQDKA
EIVNSLRKEKYEDVINSYDIKLKIGKAYFTSPNAVKVNGEIIEAKKFIIATGSSPNIPNIKGLTEVGFWTNVEALSPDKT
ISSLAIIGGRALALEFAQMYKRLGVDTTILQRSGRILPDWEPEISLSVKNYLEENDSIPIFTNVRVKEVRKGNGGKIIVT
DKGEVEADEILLATGRKPNVDLNLDAAGIELNDKGGIKVNEELRTSNPNVFAAGDVIGGPMLEALAGRQGSIAAENAIMN
VHRKIDMLSVPQVVFIEPNVAKVGLTALEAVKEGYDIDQRVVKMDNIAKARILRENYGLIKMVIDKKFRNILGVQMFGKY
AAEVINEAALALRFRATIDDLIDTIHVFPTMGESLRIAALAFTGDVSKMSCCV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 6e-77 41
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 5e-77 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA NP_344015.1 mercuric reductase BAC0651 Protein 3e-77 41