Gene Information

Name : mecR1 (SA0039)
Accession : NP_373279.1
Strain : Staphylococcus aureus N315
Genome accession: NC_002745
Putative virulence/resistance : Resistance
Product : methicillin resistance protein
Function : -
COG functional category : K : Transcription
COG ID : COG4219
EC number : -
Position : 47137 - 48894 bp
Length : 1758 bp
Strand : +
Note : -

DNA sequence :

GTGTTATCATCTTTTTTAATGTTAAGTATAATCAGTTCATTGCTCACGATATGTGTAATTTTTTTAGTGAGAATGCTCTA
TATAAAATATACTCAAAATATTATGTCACATAAGATTTGGTTATTAGTGCTCGTCTCCACGTTAATTCCATTAATACCAT
TTTACAAAATATCGAATTTTACATTTTCAAAAGATATGATGAATCGAAATGTATCTGACACGACTTCTTCGGTTAGTCAT
ATGTTAGATGGTCAACAATCATCTGTTACGAAAGACTTAGCAATTAATGTTAATCAGTTTGAGACCTCAAATATAACGTA
TATGATTCTTTTGATATGGGTATTTGGTAGTTTGTTGTGCTTATTTTATATGATTAAGGCATTCCGACAAATTGATGTTA
TTAAAAGTTCGTCATTGGAATCGTCATATCTTAATGAACGACTTAAAGTATGTCAAAGTAAGATGCAGTTCTACAAAAAG
CATATAACAATTAGTTATAGTTCAAACATTGATAATCCGATGGTATTTGGTTTAGTGAAATCCCAAATTGTACTACCAAC
TGTCGTAGTCGAAACCATGAATGACAAAGAAATTGAATATATTATTCTACATGAACTATCACATGTGAAAAGTCATGACT
TAATATTCAACCAGCTTTATGTTGTTTTTAAAATGATATTCTGGTTTAATCCTGCACTATATATAAGTAAAACAATGATG
GACAATGACTGTGAAAAAGTATGTGATAGAAACGTTTTAAAAATTTTGAATCGCCATGAACATATACGTTATGGTGAATC
GATATTAAAATGCTCTATTTTAAAATCTCAGCACATAAATAATGTGGCAGCACAATATTTACTAGGTTTTAATTCAAATA
TTAAAGAACGTGTTAAGTATATTGCACTTTATGATTCAATGCCTAAACCTAATCGAAACAAGCGTATTGTTGCGTATATT
GTATGTAGTATATCGCTTTTAATACAAGCACCGTTACTATCTGCACATGTTCAACAAGACAAATATGAAACAAATGTATC
ATATAAAAAATTAAATCAACTAGCTCCGTATTTCAAAGGATTTGATGGAAGTTTTGTGCTTTATAATGAACGGGAGCAAG
CTTATTCTATTTATAATGAACCAGAAAGTAAACAACGATATTCACCTAATTCTACTTACAAAATTTATTTAGCGTTAATG
GCATTCGACCAAAATTTACTCTCATTAAATCATACTGAACAACAATGGGATAAACATCAATATCCATTTAAAGAATGGAA
CCAAGATCAAAATTTAAATTCTTCAATGAAATATTCAGTAAATTGGTATTACGAAAATTTAAACAAACATTTAAGACAAG
ATGAGGTTAAATCTTATTTAGATCTAATTGAATATGGTAATGAAGAAATATCAGGGAATGAAAATTATTGGAATGAATCT
TCATTAAAAATTTCTGCAATAGAACAGGTTAATTTGTTGAAAAATATGAAACAACATAACATGCATTTTGATAATAAGGC
TATTGAAAAAGTTGAAAATAGTATGACTTTGAAACAAAAAGATACTTATAAATATGTAGGTAAAACTGGAACAGGAATCG
TGAATCACAAAGAAGCAAATGGATGGTTCGTAGGTTATGTTGAAACGAAAGATAATACGTATTATTTTGCTACACATTTA
AAAGGCGAAGACAATGCGAATGGCGAAAAAGCACAACAAATTTCTGAGCGTATTTTAAAAGAAATGGAGTTAATATAA

Protein sequence :

MLSSFLMLSIISSLLTICVIFLVRMLYIKYTQNIMSHKIWLLVLVSTLIPLIPFYKISNFTFSKDMMNRNVSDTTSSVSH
MLDGQQSSVTKDLAINVNQFETSNITYMILLIWVFGSLLCLFYMIKAFRQIDVIKSSSLESSYLNERLKVCQSKMQFYKK
HITISYSSNIDNPMVFGLVKSQIVLPTVVVETMNDKEIEYIILHELSHVKSHDLIFNQLYVVFKMIFWFNPALYISKTMM
DNDCEKVCDRNVLKILNRHEHIRYGESILKCSILKSQHINNVAAQYLLGFNSNIKERVKYIALYDSMPKPNRNKRIVAYI
VCSISLLIQAPLLSAHVQQDKYETNVSYKKLNQLAPYFKGFDGSFVLYNEREQAYSIYNEPESKQRYSPNSTYKIYLALM
AFDQNLLSLNHTEQQWDKHQYPFKEWNQDQNLNSSMKYSVNWYYENLNKHLRQDEVKSYLDLIEYGNEEISGNENYWNES
SLKISAIEQVNLLKNMKQHNMHFDNKAIEKVENSMTLKQKDTYKYVGKTGTGIVNHKEANGWFVGYVETKDNTYYFATHL
KGEDNANGEKAQQISERILKEMELI

• Homologs from PAI DB

Gene	GenBank Accn	Product	Virulance or Resistance	PAI or REI	Alignment Type	E-val	Identity
mecR1	NP_370566.1	methicillin resistance protein	Not tested	Type-II SCCmec	Protein	0.0	100
mecR1	NP_373279.1	methicillin resistance protein	Not tested	Type-II SCCmec	Protein	0.0	100
mecR1	YP_190061.1	methicillin-resistance regulatory protein MecR1	Not tested	Type-II SCCmec	Protein	0.0	100
mecR1	BAA82219.2	sensor transducer protein MecR1	Not tested	Type-II SCCmec	Protein	0.0	100
mecR1	YP_039516.1	methicillin resistance protein MecR1	Not tested	Type-II SCCmec	Protein	0.0	100
mecR1	BAC57479.1	signaltransducer protein MecR1	Not tested	Type-IIIinv SCCmec	Protein	0.0	99
mecR1	YP_005754042.1	methicillin resistance protein MecR1	Not tested	Type-XI SCCmec	Protein	7e-132	45

• Homologs from CARD and BacMet (resistance genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
mecR1	NP_373279.1	methicillin resistance protein	NC_002745.1122813.p0	Protein	0.0	100
mecR1	NP_373279.1	methicillin resistance protein	NC_002952.2861159.p0	Protein	0.0	100
mecR1	NP_373279.1	methicillin resistance protein	NC_002758.1120002.p0	Protein	0.0	100
mecR1	NP_373279.1	methicillin resistance protein	NC_009782.5560215.p0	Protein	0.0	100
mecR1	NP_373279.1	methicillin resistance protein	HE993884.1.gene10.p0	Protein	3e-125	48
mecR1	NP_373279.1	methicillin resistance protein	FR823292.1.gene4.p01	Protein	3e-132	45